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2QKI
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BU of 2qki by Molmil
Human C3c in complex with the inhibitor compstatin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Complement C3, ...
著者Janssen, B.J.C, Halff, E.F, Lambris, J.D, Gros, P.
登録日2007-07-11
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.
J.Biol.Chem., 282, 2007
1A1P
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BU of 1a1p by Molmil
COMPSTATIN, NMR, 21 STRUCTURES
分子名称: COMPSTATIN
著者Morikis, D, Assa-Munt, N, Sahu, A, Lambris, J.D.
登録日1997-12-12
公開日1998-04-08
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of Compstatin, a potent complement inhibitor.
Protein Sci., 7, 1998
2XWA
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BU of 2xwa by Molmil
Crystal Structure of Complement Factor D Mutant R202A
分子名称: COMPLEMENT FACTOR D, GLYCEROL
著者Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
登録日2010-11-01
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XW9
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BU of 2xw9 by Molmil
Crystal Structure of Complement Factor D mutant S183A
分子名称: COMPLEMENT FACTOR D, GLYCEROL
著者Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
登録日2010-11-01
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XWJ
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BU of 2xwj by Molmil
Crystal Structure of Complement C3b in Complex with Factor B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT C3 BETA CHAIN, ...
著者Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
登録日2010-11-04
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XWB
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BU of 2xwb by Molmil
Crystal Structure of Complement C3b in complex with Factors B and D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3B ALPHA' CHAIN, ...
著者Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
登録日2010-11-01
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2I07
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BU of 2i07 by Molmil
Human Complement Component C3b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3b, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Janssen, B.J.C, Christodoulidou, A, McCarthy, A, Lambris, J.D, Gros, P.
登録日2006-08-10
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of C3b reveals conformational changes that underlie complement activity.
Nature, 444, 2006
7BAG
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BU of 7bag by Molmil
C3b in complex with CP40
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETAMIDE, AMINO GROUP, ...
著者Lamers, C, Xue, X, Smiesko, M, van Son, H, Wagner, B, Sfyroera, G, Gros, P, Lambris, J, Ricklin, D.
登録日2020-12-15
公開日2022-01-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.
Nat Commun, 13, 2022
3L3O
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BU of 3l3o by Molmil
Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3c
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
著者Geisbrecht, B.V, Garcia, B.G.
登録日2009-12-17
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.405 Å)
主引用文献Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
2WII
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BU of 2wii by Molmil
Complement C3b in complex with factor H domains 1-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C3 BETA CHAIN, ...
著者Wu, J, Janssen, B.J.C, Gros, P.
登録日2009-05-12
公開日2009-06-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Nat. Immunol., 10, 2009
2WIN
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BU of 2win by Molmil
C3 convertase (C3bBb) stabilized by SCIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, ...
著者Wu, J, Janssen, B.J, Gros, P.
登録日2009-05-13
公開日2009-06-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Nat. Immunol., 10, 2009
3L5N
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BU of 3l5n by Molmil
Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor, ...
著者Geisbrecht, B.V, Garcia, B.L.
登録日2009-12-22
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (7.536 Å)
主引用文献Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
5O35
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BU of 5o35 by Molmil
Structure of complement proteins complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Complement factor H,Complement factor H
著者Xue, X, Wu, J, Forneris, F, Gros, P.
登録日2017-05-23
公開日2017-06-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
4H6H
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BU of 4h6h by Molmil
Crystal Structure of Staphylococcal Complement Inhibitor SCIN-B(4-85)
分子名称: Fibrinogen-binding protein
著者Garcia, B.L, Geisbrecht, B.V.
登録日2012-09-19
公開日2012-12-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5024 Å)
主引用文献A Structurally Dynamic N-terminal Helix Is a Key Functional Determinant in Staphylococcal Complement Inhibitor (SCIN) Proteins.
J.Biol.Chem., 288, 2013
3NMS
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BU of 3nms by Molmil
Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement C3c
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
著者Geisbrecht, B.V, Garcia, B.L.
登録日2010-06-22
公開日2010-08-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
4H6I
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BU of 4h6i by Molmil
Crystal Structure of Staphylococcal Complement Inhibitor SCIN-B
分子名称: Fibrinogen-binding protein
著者Garcia, B.L, Geisbrecht, B.V.
登録日2012-09-19
公開日2012-12-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.091 Å)
主引用文献A Structurally Dynamic N-terminal Helix Is a Key Functional Determinant in Staphylococcal Complement Inhibitor (SCIN) Proteins.
J.Biol.Chem., 288, 2013
5O32
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The structure of complement complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xue, X, Wu, J, Forneris, F, Gros, P.
登録日2017-05-23
公開日2017-06-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.206209 Å)
主引用文献Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
3OHX
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BU of 3ohx by Molmil
Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
著者Geisbrecht, B.V, Garcia, B.L.
登録日2010-08-18
公開日2010-09-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3T46
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Crystal structure of Staphylococcal Complement Inhibitor D (SCIN-D) at 1.5 Angstrom
分子名称: SCIN-D, SODIUM ION
著者Garcia, B.L, Geisbrecht, B.V, Summers, B.J.
登録日2011-07-25
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
3T49
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Crystal structure of truncated form of Staphylococcal Complement Inhibitor B (SCIN-B) at 1.5 Angstrom
分子名称: Fibrinogen-binding protein, GLYCEROL, SULFATE ION
著者Garcia, B.L, Geisbrecht, B.V, Summers, B.J.
登録日2011-07-25
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
3T47
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Crystal Structure of truncated form of Staphylococcal Complement Inhibitor D (SCIN-D) at 1.3 Angstrom
分子名称: SCIN-D
著者Garcia, B.L, Geisbrecht, B.V, Summers, B.J.
登録日2011-07-25
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.301 Å)
主引用文献Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
3T48
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Crystal Structure of truncated form of Staphylococcal Complement Inhibitor D (SCIN-D) at 1.5 Angstrom
分子名称: SCIN-D
著者Garcia, B.L, Geisbrecht, B.V, Summers, B.J.
登録日2011-07-25
公開日2011-11-23
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
3T4A
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BU of 3t4a by Molmil
Structure of a truncated form of Staphylococcal Complement Inhibitor B bound to human C3c at 3.4 Angstrom resolution
分子名称: Complement C3 beta chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, ...
著者Garcia, B.L, Geisbrecht, B.V, Summers, B.J.
登録日2011-07-25
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
2NOJ
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BU of 2noj by Molmil
Crystal structure of Ehp / C3d complex
分子名称: Complement C3, Efb homologous protein
著者Hammel, M, Geisbrecht, B.V.
登録日2006-10-25
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Characterization of Ehp, a Secreted Complement Inhibitory Protein from Staphylococcus aureus.
J.Biol.Chem., 282, 2007
3D5R
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Crystal Structure of Efb-C (N138A) / C3d Complex
分子名称: Complement C3, Fibrinogen-binding protein
著者Geisbrecht, B.V.
登録日2008-05-16
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008

 

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