4ZSX
 
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7FAS
 | | VAR2CSA 3D7 ectodomain core region | | 分子名称: | Erythrocyte membrane protein 1, PfEMP1 | | 著者 | Wang, L, Zhaoning, W. | | 登録日 | 2021-07-07 | | 公開日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.
Cell Discov, 7, 2021
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7WCL
 | | Crystal structure of FGFR1 kinase domain with Pemigatinib | | 分子名称: | 11-[2,6-bis(fluoranyl)-3,5-dimethoxy-phenyl]-13-ethyl-4-(morpholin-4-ylmethyl)-5,7,11,13-tetrazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),3,7-tetraen-12-one, Fibroblast growth factor receptor 1, SULFATE ION | | 著者 | Chen, X.J, Lin, Q.M, Jiang, L.Y, Qu, L.Z, Chen, Y.H. | | 登録日 | 2021-12-20 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | | 主引用文献 | Characterization of the cholangiocarcinoma drug pemigatinib against FGFR gatekeeper mutants.
Commun Chem, 5, 2022
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7FAP
 | | Structure of VAR2CSA-CSA 3D7 | | 分子名称: | 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Erythrocyte membrane protein 1, PfEMP1 | | 著者 | Wang, L, Wang, Z. | | 登録日 | 2021-07-07 | | 公開日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.
Cell Discov, 7, 2021
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5E4K
 | | Structure of ligand binding region of uPARAP at pH 7.4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, C-type mannose receptor 2, ... | | 著者 | Yuan, C, Huang, M. | | 登録日 | 2015-10-06 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding
Biochem.J., 473, 2016
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5YY5
 | | Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, Light chain, ... | | 著者 | Zhang, S, Wang, P, Zhou, P, Wang, X, Zhang, L. | | 登録日 | 2017-12-08 | | 公開日 | 2018-08-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
Cell Rep, 24, 2018
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8JI8
 | | Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, ... | | 著者 | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | | 登録日 | 2023-05-26 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Mosquitoes have evolved two types of prophenoloxidases
To Be Published
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8JIB
 | | Crystal Structure of Prophenoloxidase PPO6 from Aedes aegypti | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, TK receptor | | 著者 | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | | 登録日 | 2023-05-26 | | 公開日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Mosquitoes have evolved two types of prophenoloxidases
To Be Published
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6ITE
 | | Crystal structure of group A Streptococcal surface dehydrogenase (SDH) | | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | | 著者 | Yuan, C, Li, R, Huang, M.D. | | 登録日 | 2018-11-21 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.739 Å) | | 主引用文献 | Structural determination of group A Streptococcal surface dehydrogenase and characterization of its interaction with urokinase-type plasminogen activator receptor.
Biochem.Biophys.Res.Commun., 510, 2019
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5EW6
 | | Structure of ligand binding region of uPARAP at pH 7.4 without calcium | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type mannose receptor 2, ... | | 著者 | Yuan, C, Huang, M. | | 登録日 | 2015-11-20 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding
Biochem.J., 473, 2016
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8HLM
 | | Crystal structure of p53/BCL2 fusion complex (complex 2) | | 分子名称: | Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION | | 著者 | Guo, M, Wang, H, Wei, H, Chen, Y. | | 登録日 | 2022-11-30 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.522 Å) | | 主引用文献 | Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Nat Commun, 14, 2023
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8HLN
 | | Crystal structure of p53/BCL2 fusion complex(complex3) | | 分子名称: | Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION | | 著者 | Guo, M, Wei, H, Wang, H, Chen, Y. | | 登録日 | 2022-11-30 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.354 Å) | | 主引用文献 | Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Nat Commun, 14, 2023
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8HLL
 | | Crystal structure of p53/BCL2 fusion complex (complex 1) | | 分子名称: | Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION | | 著者 | Wei, H, Guo, M, Wang, H, Chen, Y. | | 登録日 | 2022-11-30 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Nat Commun, 14, 2023
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5Z65
 | | Crystal structure of porcine aminopeptidase N ectodomain in functional form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Sun, Y.G, Li, R, Jiang, L.G, Qiao, S.L, Zhang, G.P. | | 登録日 | 2018-01-22 | | 公開日 | 2019-01-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Characterization of the interaction between recombinant porcine aminopeptidase N and spike glycoprotein of porcine epidemic diarrhea virus.
Int. J. Biol. Macromol., 117, 2018
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8ITT
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8ITR
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5ZGD
 | | hnRNPA1 reversible amyloid core GFGGNDNFG (residues 209-217) determined by X-ray | | 分子名称: | GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHE-GLY | | 著者 | Gui, X, Xie, M, Zhao, M, Luo, F, He, J, Li, D, Liu, C. | | 登録日 | 2018-03-08 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | | 主引用文献 | Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
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5ZGL
 | | hnRNP A1 segment GGGYGGS (residues 234-240) | | 分子名称: | 7-mer peptide from Heterogeneous nuclear ribonucleoprotein A1 | | 著者 | Xie, M, Luo, F, Gui, X, Zhao, M, He, J, Li, D, Liu, C. | | 登録日 | 2018-03-09 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
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5ZXV
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6A8G
 | | The crystal structure of muPAin-1-IG in complex with muPA-SPD at pH8.5 | | 分子名称: | PHOSPHATE ION, Urokinase-type plasminogen activator chain B, muPAin-1-IG | | 著者 | Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z. | | 登録日 | 2018-07-08 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.
J.Med.Chem., 62, 2019
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6A8N
 | | The crystal structure of muPAin-1-IG-2 in complex with muPA-SPD at pH8.5 | | 分子名称: | CYS-PRO-ALA-TYR-SER-ARG-TYR-ILE-GLY-CYS, Urokinase-type plasminogen activator B | | 著者 | Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z. | | 登録日 | 2018-07-09 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | | 主引用文献 | Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.
J.Med.Chem., 62, 2019
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5W0X
 | | Crystal structure of mouse TOR signaling pathway regulator-like (TIPRL) delta 94-103 | | 分子名称: | TIP41-like protein | | 著者 | Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y. | | 登録日 | 2017-06-01 | | 公開日 | 2018-01-17 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.717 Å) | | 主引用文献 | Methylation-regulated decommissioning of multimeric PP2A complexes.
Nat Commun, 8, 2017
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5W0W
 | | Crystal structure of Protein Phosphatase 2A bound to TIPRL | | 分子名称: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... | | 著者 | Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y. | | 登録日 | 2017-06-01 | | 公開日 | 2018-01-17 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Methylation-regulated decommissioning of multimeric PP2A complexes.
Nat Commun, 8, 2017
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4I5N
 | | Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation | | 分子名称: | CALCIUM ION, MANGANESE (II) ION, Microcystin-LR (MCLR) bound form, ... | | 著者 | Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y. | | 登録日 | 2012-11-28 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
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4I5J
 | | PP2A PR70 Holoenzyme | | 分子名称: | CALCIUM ION, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha | | 著者 | Xing, Y, Jeffery, P.D, Shi, Y. | | 登録日 | 2012-11-28 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | | 主引用文献 | Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
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