6Z8G
 
 | | Crystal structure of VSG13 soaked in 0.5 M used to phase VSG13 to solve the structure. | | 分子名称: | BROMIDE ION, SULFATE ION, Variant surface glycoprotein MITat 1.13, ... | | 著者 | Stebbins, C.E, Hempelmann, A, Van Straaten, M, Zeelen, J. | | 登録日 | 2020-06-02 | | 公開日 | 2021-03-17 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
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6Z7D
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6Z79
 | | Variant Surface Glycoprotein VSGsur, I3C ("Magic Triangle") derivative used for phasing of the structure and subsequently as a model for molecular replacement of native, mutants, and drug soaks. | | 分子名称: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Zeelen, J.P, Straaten van, M, Stebbins, C.E. | | 登録日 | 2020-05-30 | | 公開日 | 2021-03-17 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
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6Z8H
 | | Crystal structure of Variant Surface Glycoprotein VSG13 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variant surface glycoprotein MITat 1.13, ... | | 著者 | Stebbins, C.E, Hempelmann, A, Van Straaten, M, Zeelen, J. | | 登録日 | 2020-06-02 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
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6Z7C
 | | Variant Surface Glycoprotein VSGsur mutant H122A | | 分子名称: | Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Zeelen, J.P, Straaten van, M, Stebbins, C.E. | | 登録日 | 2020-05-30 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
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6Z7E
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6Z7A
 | | Variant Surface Glycoprotein VSGsur | | 分子名称: | Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Zeelen, J.P, Straaten van, M, Stebbins, C.E, Hashemi, H. | | 登録日 | 2020-05-30 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | A Parasite Coat Protein Binds Suramin to Confer Drug Resistance
Nat Microbiol, 6, 2021
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1MAJ
 | | SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | | 分子名称: | IGG2A-KAPPA 26-10 FV (LIGHT CHAIN) | | 著者 | Constantine, K.L, Friedrichs, M.S, Metzler, W.J, Wittekind, M, Hensley, P, Mueller, L. | | 登録日 | 1993-09-16 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of an isolated antibody VL domain.
J.Mol.Biol., 236, 1994
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1MAK
 | | SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | | 分子名称: | IGG2A-KAPPA 26-10 FV (LIGHT CHAIN) | | 著者 | Constantine, K.L, Friedrichs, M.S, Metzler, W.J, Wittekind, M, Hensley, P, Mueller, L. | | 登録日 | 1993-09-16 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of an isolated antibody VL domain.
J.Mol.Biol., 236, 1994
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1UCB
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6MWW
 | | LasR LBD:BB0126 complex | | 分子名称: | 4-[3-(methylsulfonyl)phenoxy]-N-[(1R,3R,5R)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, Transcriptional regulator LasR | | 著者 | Bassler, B.L, Paczkowski, J.E. | | 登録日 | 2018-10-30 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
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6MWL
 | | LasR LBD:mBTL complex | | 分子名称: | 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, Transcriptional regulator LasR | | 著者 | Bassler, B.L, Paczkowski, J.E. | | 登録日 | 2018-10-29 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
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6MWZ
 | | LasR LBD T75V/Y93F/A127W:BB0126 | | 分子名称: | 4-[3-(methylsulfonyl)phenoxy]-N-[(1S,3S,5S)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, ALA-HIS-HIS-HIS-HIS-ALA, Transcriptional regulator LasR | | 著者 | Bassler, B.L, Paczkowski, J.E. | | 登録日 | 2018-10-30 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.657 Å) | | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
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6MVM
 | | LasR LBD L130F:3OC14HSL complex | | 分子名称: | 3-oxo-N-[(3S)-2-oxooxolan-3-yl]tetradecanamide, Transcriptional regulator LasR | | 著者 | Paczkowski, J.E, Bassler, B.L. | | 登録日 | 2018-10-26 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
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6MWH
 | | LasR LBD:BB0020 complex | | 分子名称: | 2-(3-bromophenoxy)-N-[(1S,2S,3R,5S)-2-hydroxybicyclo[3.1.0]hexan-3-yl]acetamide, Transcriptional regulator LasR | | 著者 | Bassler, B.L, Paczkowski, J.E. | | 登録日 | 2018-10-29 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
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1TSR
 | | P53 CORE DOMAIN IN COMPLEX WITH DNA | | 分子名称: | DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR), ... | | 著者 | Cho, Y, Gorina, S, Jeffrey, P, Pavletich, N. | | 登録日 | 1995-07-28 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265, 1994
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2HJE
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4GYO
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4I5J
 | | PP2A PR70 Holoenzyme | | 分子名称: | CALCIUM ION, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha | | 著者 | Xing, Y, Jeffery, P.D, Shi, Y. | | 登録日 | 2012-11-28 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | | 主引用文献 | Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
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3IEI
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2PII
 | | PII, GLNB PRODUCT | | 分子名称: | PII | | 著者 | Carr, P.D, Cheah, E, Suffolk, P.M, Ollis, D.L. | | 登録日 | 1995-05-02 | | 公開日 | 1996-06-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray structure of the signal transduction protein from Escherichia coli at 1.9 A.
Acta Crystallogr.,Sect.D, 52, 1996
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1BQL
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2HJ9
 | | Crystal structure of the Autoinducer-2-bound form of Vibrio harveyi LuxP complexed with the periplasmic domain of LuxQ | | 分子名称: | 3A-METHYL-5,6-DIHYDRO-FURO[2,3-D][1,3,2]DIOXABOROLE-2,2,6,6A-TETRAOL, Autoinducer 2 sensor kinase/phosphatase luxQ, Autoinducer 2-binding periplasmic protein luxP | | 著者 | Neiditch, M.B, Hughson, F.M. | | 登録日 | 2006-06-30 | | 公開日 | 2006-09-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing.
Cell(Cambridge,Mass.), 126, 2006
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2NPP
 | | Structure of the Protein Phosphatase 2A Holoenzyme | | 分子名称: | MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ... | | 著者 | Xu, Y, Chen, Y, Xing, Y, Chao, Y, Shi, Y. | | 登録日 | 2006-10-28 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the protein phosphatase 2A holoenzyme
Cell(Cambridge,Mass.), 127, 2006
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2NRF
 | | Crystal Structure of GlpG, a Rhomboid family intramembrane protease | | 分子名称: | Protein GlpG | | 著者 | Wu, Z, Yan, N, Feng, L, Yan, H, Gu, L, Shi, Y. | | 登録日 | 2006-11-02 | | 公開日 | 2006-11-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.
Nat.Struct.Mol.Biol., 13, 2006
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