2HJ9

Crystal structure of the Autoinducer-2-bound form of Vibrio harveyi LuxP complexed with the periplasmic domain of LuxQ

Summary for 2HJ9

Entry DOI	10.2210/pdb2hj9/pdb
Related	1JX6 1ZHH 2hje
Descriptor	Autoinducer 2-binding periplasmic protein luxP, Autoinducer 2 sensor kinase/phosphatase luxQ, 3A-METHYL-5,6-DIHYDRO-FURO[2,3-D][1,3,2]DIOXABOROLE-2,2,6,6A-TETRAOL, ... (4 entities in total)
Functional Keywords	periplasmic binding protein, per/arnt/simple-minded (pas) fold, autoinducer-2 (ai-2), quorum sensing, histidine sensor kinase, signaling protein
Biological source	Vibrio harveyi More
Cellular location	Periplasm (Probable): P54300 Cell inner membrane; Multi-pass membrane protein (Probable): P54302
Total number of polymer chains	4
Total formula weight	127602.31
Authors	Neiditch, M.B.,Hughson, F.M. (deposition date: 2006-06-30, release date: 2006-09-26, Last modification date: 2024-02-14)
Primary citation	Neiditch, M.B.,Federle, M.J.,Pompeani, A.J.,Kelly, R.C.,Swem, D.L.,Jeffrey, P.D.,Bassler, B.L.,Hughson, F.M. Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing. Cell(Cambridge,Mass.), 126:1095-1108, 2006 Cited by PubMed: 16990134 DOI: 10.1016/j.cell.2006.07.032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.34 Å)

Structure validation