4X0J
 
 | | Trypanosoma brucei haptoglobin-haemoglobin receptor | | 分子名称: | Haptoglobin-hemoglobin receptor | | 著者 | Lane-Serff, H, MacGregor, P, Lowe, E.D, Carrington, M, Higgins, M.K. | | 登録日 | 2014-11-21 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor.
Elife, 3, 2014
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4X0L
 | | Human haptoglobin-haemoglobin complex | | 分子名称: | CACODYLATE ION, GLYCEROL, Haptoglobin, ... | | 著者 | Lane-Serff, H, MacGregor, P, Lowe, E.D, Carrington, M, Higgins, M.K. | | 登録日 | 2014-11-21 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor.
Elife, 3, 2014
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7PI6
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7PI2
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7PHU
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7PI7
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7PHW
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6XZ6
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6Z3T
 | | Structure of canine Sec61 inhibited by mycolactone | | 分子名称: | Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, Protein transport protein Sec61 subunit gamma, ... | | 著者 | Gerard, S.F, Higgins, M.K. | | 登録日 | 2020-05-21 | | 公開日 | 2020-07-22 | | 最終更新日 | 2020-08-19 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | Structure of the Inhibited State of the Sec Translocon.
Mol.Cell, 79, 2020
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6ZDX
 | | RIFIN variable region bound to LILRB1 ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leukocyte immunoglobulin-like receptor subfamily B member 1, ... | | 著者 | Harrison, T.E, Higgins, M.K. | | 登録日 | 2020-06-15 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for RIFIN-mediated activation of LILRB1 in malaria.
Nature, 587, 2020
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6SNY
 | | Synthetic mimic of an EPCR-binding PfEMP1 bound to EPCR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, ... | | 著者 | Barber, N.M, Higgins, M.K. | | 登録日 | 2019-08-27 | | 公開日 | 2019-09-04 | | 最終更新日 | 2021-01-20 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein.
Msphere, 6, 2021
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5MZA
 | | The DBLb domain of PF11_0521 PfEMP1 bound to human ICAM-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Erythrocyte membrane protein 1 (PfEMP1), ... | | 著者 | Lennartz, F, Higgins, M.K. | | 登録日 | 2017-01-31 | | 公開日 | 2017-03-22 | | 最終更新日 | 2020-10-07 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
Cell Host Microbe, 21, 2017
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5NST
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6ELU
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5JDO
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5LGD
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5MI0
 | | A thermally stabilised version of Plasmodium falciparum RH5 | | 分子名称: | MONOCLONAL ANTIBODY 9AD4, Reticulocyte binding-like protein 5,Reticulocyte binding protein 5 | | 著者 | Campeotto, I, Goldenzweig, A, Davey, J, Barfod, L, Marshall, J.M, Silk, S.E, Wright, K.E, Draper, S.J, Higgins, M.K, Fleishman, S.J. | | 登録日 | 2016-11-27 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6SOZ
 | | Glycosylated Trypanosoma brucei transferrin receptor in complex with human transferrin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, ... | | 著者 | Trevor, C, Carrington, M, Higgins, M.K. | | 登録日 | 2019-08-30 | | 公開日 | 2019-11-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.
Nat Microbiol, 4, 2019
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6R2S
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6RCV
 | | PfRH5 bound to monoclonal antibodies R5.011 and R5.016 | | 分子名称: | R5.011 heavy chain, R5.011 light chain, R5.016 heavy chain, ... | | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.582 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCO
 | | PfRH5-binding monoclonal antibody R5.004 | | 分子名称: | ACETATE ION, GLYCEROL, R5.004 heavy chain, ... | | 著者 | Alanine, D.G.W, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCU
 | | PfRH5 bound to monoclonal antibodies R5.004 and R5.016 | | 分子名称: | R5.004 heavy chain, R5.004 light chain, R5.016 heavy chain, ... | | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (4.005 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCQ
 | | PfRH5-binding monoclonal antibody R5.011 | | 分子名称: | ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ... | | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCS
 | | PfRH5-binding monoclonal antibody R5.016 | | 分子名称: | ACETATE ION, R5.016 heavy chain, R5.016 light chain, ... | | 著者 | Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6S8T
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