6RCO

PfRH5-binding monoclonal antibody R5.004

Summary for 6RCO

• Entry DOI: 10.2210/pdb6rco/pdb
• Descriptor: R5.004 heavy chain, R5.004 light chain, GLYCEROL, ... (5 entities in total)
• Functional Keywords: plasmodium falciparum erythrocyte invasion neutralisation human monoclonal antibody, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 96021.60

Authors

Alanine, D.G.W.,Draper, S.J.,Higgins, M.K. (deposition date: 2019-04-11, release date: 2019-06-26, Last modification date: 2019-08-21)

• Primary citation: Alanine, D.G.W.,Quinkert, D.,Kumarasingha, R.,Mehmood, S.,Donnellan, F.R.,Minkah, N.K.,Dadonaite, B.,Diouf, A.,Galaway, F.,Silk, S.E.,Jamwal, A.,Marshall, J.M.,Miura, K.,Foquet, L.,Elias, S.C.,Labbe, G.M.,Douglas, A.D.,Jin, J.,Payne, R.O.,Illingworth, J.J.,Pattinson, D.J.,Pulido, D.,Williams, B.G.,de Jongh, W.A.,Wright, G.J.,Kappe, S.H.I.,Robinson, C.V.,Long, C.A.,Crabb, B.S.,Gilson, P.R.,Higgins, M.K.,Draper, S.J.; Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.; Cell, 178:216-228.e21, 2019; PubMed: 31204103; DOI: 10.1016/j.cell.2019.05.025

Experimental method

X-RAY DIFFRACTION (1.66 Å)