2IQD
| Crystal Structure of Aldose Reductase complexed with Lipoic Acid | Descriptor: | Aldose reductase, LIPOIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Harrison, D.H.T, Carlson, E, Pape, E, Brownlee, J.M. | Deposit date: | 2006-10-13 | Release date: | 2006-11-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes. Bioorg.Chem., 34, 2006
|
|
1T47
| Structure of fe2-HPPD bound to NTBC | Descriptor: | 2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHYLENE}CYCLOHEXANE-1,3-DIONE, 4-hydroxyphenylpyruvate dioxygenase, FE (II) ION | Authors: | Brownlee, J, Johnson-Winters, K, Harrison, D.H.T, Moran, G.R. | Deposit date: | 2004-04-28 | Release date: | 2004-06-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the Ferrous Form of (4-Hydroxyphenyl)pyruvate Dioxygenase from Streptomyces avermitilis in Complex with the Therapeutic Herbicide, NTBC Biochemistry, 43, 2004
|
|
1XPL
| Crystal Structure of Staphylococcus aureus HMG-COA Synthase with Acetoacetyl-COA and Acetylated Cysteine | Descriptor: | 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, SULFATE ION | Authors: | Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. | Deposit date: | 2004-10-08 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47, 2004
|
|
1XPM
| Crystal Structure of Staphylococcus aureus HMG-COA Synthase with HMG-CoA and Acetoacetyl-COA and Acetylated Cysteine | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, ... | Authors: | Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. | Deposit date: | 2004-10-08 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47, 2004
|
|
1XPK
| CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS HMG-COA SYNTHASE WITH HMG-CoA AND WITH ACETOACETYL-COA AND ACETYLATED CYSTEINE | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, ... | Authors: | Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. | Deposit date: | 2004-10-08 | Release date: | 2004-11-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47, 2004
|
|
1XGD
| Apo R268A human aldose reductase | Descriptor: | Aldose reductase | Authors: | Brownlee, J.M, Bohren, K.M, Milne, A.C, Gabbay, K.H, Harrison, D.H.T. | Deposit date: | 2004-09-16 | Release date: | 2005-03-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of Apo R268A human aldose reductase: Hinges and latches that control the kinetic mechanism Biochim.Biophys.Acta, 1748, 2005
|
|
1A7J
| PHOSPHORIBULOKINASE FROM RHODOBACTER SPHEROIDES | Descriptor: | PHOSPHORIBULOKINASE, SULFATE ION | Authors: | Harrison, D.H.T, Runquist, J, Holub, A, Miziorko, H. | Deposit date: | 1998-03-16 | Release date: | 1998-06-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of phosphoribulokinase from Rhodobacter sphaeroides reveals a fold similar to that of adenylate kinase. Biochemistry, 37, 1998
|
|
1AZ1
| ALRESTATIN BOUND TO C298A/W219Y MUTANT HUMAN ALDOSE REDUCTASE | Descriptor: | ALDOSE REDUCTASE, ALRESTATIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Harrison, D.H.T, Bohren, K.M, Petsko, G.A, Ringe, D, Gabbay, K.H. | Deposit date: | 1997-11-24 | Release date: | 1998-03-18 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant. Biochemistry, 36, 1997
|
|
2INE
| |
2INZ
| Crystal Structure of Aldose Reductase complexed with 2-Hydroxyphenylacetic Acid | Descriptor: | (2-HYDROXYPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Harrison, D.H.T, Pape, E, Carlson, E, Brownlee, J.M. | Deposit date: | 2006-10-09 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes. Bioorg.Chem., 34, 2006
|
|
2IPW
| Crystal Structure of C298A W219Y Aldose Reductase complexed with Dichlorophenylacetic acid | Descriptor: | (2,6-DICHLOROPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Harrison, D.H.T, Pape, E, Brownlee, J.M. | Deposit date: | 2006-10-12 | Release date: | 2006-11-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes. Bioorg.Chem., 34, 2006
|
|
2ISF
| |
2IQ0
| |
2IS7
| Crystal Structure of Aldose Reductase complexed with Dichlorophenylacetic acid | Descriptor: | (2,6-DICHLOROPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Harrison, D.H.T, Milne, A, Brownlee, J.M. | Deposit date: | 2006-10-16 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes. Bioorg.Chem., 34, 2006
|
|
1IK4
| X-ray Structure of Methylglyoxal Synthase from E. coli Complexed with Phosphoglycolohydroxamic Acid | Descriptor: | METHYLGLYOXAL SYNTHASE, PHOSPHOGLYCOLOHYDROXAMIC ACID | Authors: | Marks, G.T, Harris, T.K, Massiah, M.A, Mildvan, A.S, Harrison, D.H.T. | Deposit date: | 2001-05-02 | Release date: | 2001-09-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanistic implications of methylglyoxal synthase complexed with phosphoglycolohydroxamic acid as observed by X-ray crystallography and NMR spectroscopy. Biochemistry, 40, 2001
|
|
2R5V
| Hydroxymandelate Synthase Crystal Structure | Descriptor: | (2S)-hydroxy(4-hydroxyphenyl)ethanoic acid, COBALT (II) ION, PCZA361.1, ... | Authors: | Brownlee, J.M, He, P, Moran, G.R, Harrison, D.H.T. | Deposit date: | 2007-09-04 | Release date: | 2008-03-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Two roads diverged: the structure of hydroxymandelate synthase from Amycolatopsis orientalis in complex with 4-hydroxymandelate. Biochemistry, 47, 2008
|
|
1EGH
| |
1B93
| METHYLGLYOXAL SYNTHASE FROM ESCHERICHIA COLI | Descriptor: | FORMIC ACID, PHOSPHATE ION, PROTEIN (METHYLGLYOXAL SYNTHASE) | Authors: | Saadat, D, Harrison, D.H.T. | Deposit date: | 1999-02-23 | Release date: | 1999-03-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of methylglyoxal synthase from Escherichia coli. Structure Fold.Des., 7, 1999
|
|