1XGD

Apo R268A human aldose reductase

Summary for 1XGD

• Entry DOI: 10.2210/pdb1xgd/pdb
• Descriptor: Aldose reductase (2 entities in total)
• Functional Keywords: akr, akr1b1, nadph, diabetes, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P15121
• Total number of polymer chains: 1
• Total formula weight: 35681.03

Authors

Brownlee, J.M.,Bohren, K.M.,Milne, A.C.,Gabbay, K.H.,Harrison, D.H.T. (deposition date: 2004-09-16, release date: 2005-03-29, Last modification date: 2023-08-23)

• Primary citation: Bohren, K.M.,Brownlee, J.M.,Milne, A.C.,Gabbay, K.H.,Harrison, D.H.T.; The structure of Apo R268A human aldose reductase: Hinges and latches that control the kinetic mechanism; Biochim.Biophys.Acta, 1748:201-212, 2005; PubMed: 15769597; DOI: 10.1016/j.bbapap.2005.01.006

Experimental method

X-RAY DIFFRACTION (2.1 Å)