2FFL
 
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2QVW
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7THB
 | | Crystal structure of an RNA-5'/DNA-3' strand exchange junction | | 分子名称: | DNA (5'-D(*GP*AP*TP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*TP*AP*AP*GP*CP*AP*GP*CP*AP*TP*C)-3'), RNA (5'-R(*AP*GP*CP*UP*UP*AP*C)-3') | | 著者 | Cofsky, J.C, Knott, G.J, Gee, C.L, Doudna, J.A. | | 登録日 | 2022-01-10 | | 公開日 | 2022-04-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Crystal structure of an RNA/DNA strand exchange junction.
Plos One, 17, 2022
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8VXA
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8VXC
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8VXY
 | | Structure of HamA(E138A,K140A)B-plasmid DNA complex from the Escherichia coli Hachiman defense system | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, HamA, HamB, ... | | 著者 | Tuck, O.T, Hu, J.J, Doudna, J.A. | | 登録日 | 2024-02-06 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Hachiman is a genome integrity sensor.
Biorxiv, 2024
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8VX9
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3FRX
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6VPC
 | | Structure of the SpCas9 DNA adenine base editor - ABE8e | | 分子名称: | CRISPR-associated endonuclease Cas9, Cas9 (SpCas9) single-guide RNA (sgRNA), DNA non-target strand (NTS), ... | | 著者 | Knott, G.J, Lapinaite, A, Doudna, J.A. | | 登録日 | 2020-02-03 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | DNA capture by a CRISPR-Cas9-guided adenine base editor.
Science, 369, 2020
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1GID
 | | CRYSTAL STRUCTURE OF A GROUP I RIBOZYME DOMAIN: PRINCIPLES OF RNA PACKING | | 分子名称: | COBALT HEXAMMINE(III), MAGNESIUM ION, P4-P6 RNA RIBOZYME DOMAIN | | 著者 | Cate, J.H, Gooding, A.R, Podell, E, Zhou, K, Golden, B.L, Kundrot, C.E, Cech, T.R, Doudna, J.A. | | 登録日 | 1996-08-22 | | 公開日 | 1996-12-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a group I ribozyme domain: principles of RNA packing.
Science, 273, 1996
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3T4B
 | | Crystal Structure of the HCV IRES pseudoknot domain | | 分子名称: | HCV IRES pseudoknot domain plus crystallization module, NICKEL (II) ION | | 著者 | Berry, K.E, Waghray, S, Mortimer, S.A, Bai, Y, Doudna, J.A. | | 登録日 | 2011-07-25 | | 公開日 | 2011-10-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | | 主引用文献 | Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning.
Structure, 19, 2011
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5I4A
 | | X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA | | 分子名称: | Argonaute protein, RNA (5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*U)-3') | | 著者 | Doxzen, K.W, Kaya, E, Knoll, K.R, Wilson, R.C, Strutt, S.C, Kranzusch, P.J, Doudna, J.A. | | 登録日 | 2016-02-11 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | | 主引用文献 | A bacterial Argonaute with noncanonical guide RNA specificity.
Proc.Natl.Acad.Sci.USA, 113, 2016
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7S3H
 | | Cas9:sgRNA:DNA (S. pyogenes) with 0 RNA:DNA base pairs, open-protein/linear-DNA conformation | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ... | | 著者 | Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A. | | 登録日 | 2021-09-06 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
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7S37
 | | Cas9:sgRNA (S. pyogenes) in the open-protein conformation | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Single-guide RNA | | 著者 | Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A. | | 登録日 | 2021-09-04 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
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7S38
 | | Cas9:sgRNA:DNA (S. pyogenes) forming a 3-base-pair R-loop | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ... | | 著者 | Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A. | | 登録日 | 2021-09-04 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
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7S36
 | | Cas9:sgRNA:DNA (S. pyogenes) with 0 RNA:DNA base pairs, closed-protein/bent-DNA conformation | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ... | | 著者 | Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A. | | 登録日 | 2021-09-04 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
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5K4C
 | | Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2 | | 分子名称: | Eukaryotic translation initiation factor 3 subunit D, GLYCEROL | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. | | 登録日 | 2016-05-20 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
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5K4B
 | | Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 1 | | 分子名称: | CHLORIDE ION, Eukaryotic translation initiation factor 3 subunit D | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. | | 登録日 | 2016-05-20 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | | 主引用文献 | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
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5K4D
 | | Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 3 | | 分子名称: | Eukaryotic translation initiation factor 3 subunit D | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. | | 登録日 | 2016-05-20 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
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4TXY
 | | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog | | 分子名称: | Cyclic AMP-GMP synthase, MAGNESIUM ION | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | | 登録日 | 2014-07-07 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.0001 Å) | | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
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4TY0
 | | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG | | 分子名称: | ACETATE ION, Cyclic AMP-GMP synthase, MAGNESIUM ION, ... | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | | 登録日 | 2014-07-07 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
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4TXZ
 | | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP | | 分子名称: | Cyclic AMP-GMP synthase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | | 登録日 | 2014-07-07 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
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2OIH
 | | Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+ | | 分子名称: | HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A | | 著者 | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | | 登録日 | 2007-01-11 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
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2OJ3
 | | Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+) | | 分子名称: | COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ... | | 著者 | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | | 登録日 | 2007-01-12 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
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4WYQ
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