1G6R
| A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX | 分子名称: | ALPHA T CELL RECEPTOR, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ... | 著者 | Degano, M, Garcia, K.C, Apostolopoulos, V, Rudolph, M.G, Teyton, L, Wilson, I.A. | 登録日 | 2000-11-07 | 公開日 | 2000-11-15 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A functional hot spot for antigen recognition in a superagonist TCR/MHC complex. Immunity, 12, 2000
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1MAS
| PURINE NUCLEOSIDE HYDROLASE | 分子名称: | INOSINE-URIDINE NUCLEOSIDE N-RIBOHYDROLASE, POTASSIUM ION | 著者 | Degano, M, Gopaul, D.N, Scapin, G, Schramm, V.L, Sacchettini, J.C. | 登録日 | 1995-12-18 | 公開日 | 1996-08-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Three-dimensional structure of the inosine-uridine nucleoside N-ribohydrolase from Crithidia fasciculata. Biochemistry, 35, 1996
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2MAS
| PURINE NUCLEOSIDE HYDROLASE WITH A TRANSITION STATE INHIBITOR | 分子名称: | 2-(4-AMINO-PHENYL)-5-HYDROXYMETHYL-PYRROLIDINE-3,4-DIOL, CALCIUM ION, INOSINE-URIDINE NUCLEOSIDE N-RIBOHYDROLASE | 著者 | Degano, M, Schramm, V.L, Sacchettini, J.C. | 登録日 | 1996-10-17 | 公開日 | 1997-08-12 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor. Biochemistry, 37, 1998
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6S83
| Crystal structure of methionine adenosyltransferase from Pyrococcus furiosus in complex with AMPPCP, SAM, and PCP | 分子名称: | MAGNESIUM ION, METHYLENEDIPHOSPHONIC ACID, PHOSPHATE ION, ... | 著者 | Degano, M, Minici, C, Porcelli, M. | 登録日 | 2019-07-08 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.336 Å) | 主引用文献 | Structures of catalytic cycle intermediates of the Pyrococcus furiosus methionine adenosyltransferase demonstrate negative cooperativity in the archaeal orthologues. J.Struct.Biol., 210, 2020
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6S81
| Crystal structure of methionine adenosyltransferase from Pyrococcus furiosus | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MANGANESE (II) ION, ... | 著者 | Degano, M, Minici, C, Porcelli, M. | 登録日 | 2019-07-08 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.784 Å) | 主引用文献 | Structures of catalytic cycle intermediates of the Pyrococcus furiosus methionine adenosyltransferase demonstrate negative cooperativity in the archaeal orthologues. J.Struct.Biol., 210, 2020
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6RMJ
| Crystal structure of human NGR-TNF | 分子名称: | Tumor necrosis factor | 著者 | Degano, M, Garau, G. | 登録日 | 2019-05-07 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling. Int J Mol Sci, 20, 2019
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6ZTD
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1Q8F
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5IFH
| Crystal structure of the BCR Fab fragment from subset #2 case P11475 | 分子名称: | Heavy chain of the Fab fragment from BCR derived from the P11475 CLL clone, Light chain of the Fab fragment from BCR derived from the P11475 CLL clone | 著者 | Minici, C, Degano, M. | 登録日 | 2016-02-26 | 公開日 | 2017-03-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | 主引用文献 | Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia. Nat Commun, 8, 2017
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3MKM
| Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form) | 分子名称: | CALCIUM ION, Putative uncharacterized protein YeiK | 著者 | Garau, G, Fornili, A, Giabbai, B, Degano, M. | 登録日 | 2010-04-15 | 公開日 | 2010-12-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Energy Landscapes Associated with Macromolecular Conformational Changes from Endpoint Structures J.Am.Chem.Soc., 132, 2010
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1BYA
| CRYSTAL STRUCTURES OF SOYBEAN BETA-AMYLASE REACTED WITH BETA-MALTOSE AND MALTAL: ACTIVE SITE COMPONENTS AND THEIR APPARENT ROLE IN CATALYSIS | 分子名称: | BETA-AMYLASE, SULFATE ION | 著者 | Mikami, B, Degano, M, Hehre, E.J, Sacchettini, J.C. | 登録日 | 1994-01-25 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of soybean beta-amylase reacted with beta-maltose and maltal: active site components and their apparent roles in catalysis. Biochemistry, 33, 1994
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3G5I
| Crystal Structure of the E.coli RihA pyrimidine nucleosidase bound to a iminoribitol-based inhibitor | 分子名称: | (2S,3S,4R,5R)-2-(3,4-diaminophenyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol, BETA-MERCAPTOETHANOL, CALCIUM ION, ... | 著者 | Garau, G, Muzzolini, L, Tornaghi, P, Degano, M. | 登録日 | 2009-02-05 | 公開日 | 2010-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor. Bmc Struct.Biol., 10, 2010
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1BYB
| CRYSTAL STRUCTURES OF SOYBEAN BETA-AMYLASE REACTED WITH BETA-MALTOSE AND MALTAL: ACTIVE SITE COMPONENTS AND THEIR APPARENT ROLE IN CATALYSIS | 分子名称: | BETA-AMYLASE, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Mikami, B, Degano, M, Hehre, E.J, Sacchettini, J.C. | 登録日 | 1994-01-25 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of soybean beta-amylase reacted with beta-maltose and maltal: active site components and their apparent roles in catalysis. Biochemistry, 33, 1994
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1BYC
| CRYSTAL STRUCTURES OF SOYBEAN BETA-AMYLASE REACTED WITH BETA-MALTOSE AND MALTAL: ACTIVE SITE COMPONENTS AND THEIR APPARENT ROLE IN CATALYSIS | 分子名称: | BETA-AMYLASE, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Mikami, B, Degano, M, Hehre, E.J, Sacchettini, J.C. | 登録日 | 1994-01-25 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of soybean beta-amylase reacted with beta-maltose and maltal: active site components and their apparent roles in catalysis. Biochemistry, 33, 1994
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1BYD
| CRYSTAL STRUCTURES OF SOYBEAN BETA-AMYLASE REACTED WITH BETA-MALTOSE AND MALTAL: ACTIVE SITE COMPONENTS AND THEIR APPARENT ROLE IN CATALYSIS | 分子名称: | BETA-AMYLASE, SULFATE ION, alpha-D-glucopyranose-(1-4)-2-deoxy-beta-D-arabino-hexopyranose | 著者 | Mikami, B, Degano, M, Hehre, E.J, Sacchettini, J.C. | 登録日 | 1994-01-25 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of soybean beta-amylase reacted with beta-maltose and maltal: active site components and their apparent roles in catalysis. Biochemistry, 33, 1994
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3B9X
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8OI7
| Trichomonas vaginalis riboside hydrolase | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Inosine-uridine preferring nucleoside hydrolase family protein, ... | 著者 | Patrone, M, Stockman, B.J, Degano, M. | 登録日 | 2023-03-22 | 公開日 | 2023-08-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A riboside hydrolase that salvages both nucleobases and nicotinamide in the auxotrophic parasite Trichomonas vaginalis. J.Biol.Chem., 299, 2023
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8OIB
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8OIC
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8OIA
| Trichomonas vaginalis riboside hydrolase in complex with D-ribose | 分子名称: | CALCIUM ION, GLYCEROL, Inosine-uridine preferring nucleoside hydrolase family protein, ... | 著者 | Patrone, M, Stockman, B.J, Degano, M. | 登録日 | 2023-03-22 | 公開日 | 2023-08-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A riboside hydrolase that salvages both nucleobases and nicotinamide in the auxotrophic parasite Trichomonas vaginalis. J.Biol.Chem., 299, 2023
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8OI9
| Trichomonas vaginalis riboside hydrolase in complex with 5-methyluridine | 分子名称: | 5-methyluridine, CALCIUM ION, Inosine-uridine preferring nucleoside hydrolase family protein, ... | 著者 | Patrone, M, Stockman, B.J, Degano, M. | 登録日 | 2023-03-22 | 公開日 | 2023-08-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A riboside hydrolase that salvages both nucleobases and nicotinamide in the auxotrophic parasite Trichomonas vaginalis. J.Biol.Chem., 299, 2023
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3MKN
| Crystal structure of the E. coli pyrimidine nucleosidase YeiK bound to a competitive inhibitor | 分子名称: | (2S,3S,4R,5R)-2-(3,4-diaminophenyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol, CALCIUM ION, Putative uncharacterized protein YeiK | 著者 | Garau, G, Fornili, A, Giabbai, B, Degano, M. | 登録日 | 2010-04-15 | 公開日 | 2010-12-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Energy Landscapes Associated with Macromolecular Conformational Changes from Endpoint Structures J.Am.Chem.Soc., 132, 2010
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5DRX
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5DRW
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1YOE
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