2MAS
PURINE NUCLEOSIDE HYDROLASE WITH A TRANSITION STATE INHIBITOR
Summary for 2MAS
Entry DOI | 10.2210/pdb2mas/pdb |
Descriptor | INOSINE-URIDINE NUCLEOSIDE N-RIBOHYDROLASE, CALCIUM ION, 2-(4-AMINO-PHENYL)-5-HYDROXYMETHYL-PYRROLIDINE-3,4-DIOL, ... (4 entities in total) |
Functional Keywords | purine nucleoside hydrolase, inosine, uridine, iu-nh, hydrolase, purine nucleosidase |
Biological source | Crithidia fasciculata |
Total number of polymer chains | 4 |
Total formula weight | 137883.26 |
Authors | Degano, M.,Schramm, V.L.,Sacchettini, J.C. (deposition date: 1996-10-17, release date: 1997-08-12, Last modification date: 2024-05-22) |
Primary citation | Degano, M.,Almo, S.C.,Sacchettini, J.C.,Schramm, V.L. Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor. Biochemistry, 37:6277-6285, 1998 Cited by PubMed: 9572842DOI: 10.1021/bi973012e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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