6RMJ

Crystal structure of human NGR-TNF

Summary for 6RMJ

• Entry DOI: 10.2210/pdb6rmj/pdb
• Descriptor: Tumor necrosis factor (2 entities in total)
• Functional Keywords: tnf alpha, tnfa, cytokine, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 53887.04

Authors

Degano, M.,Garau, G. (deposition date: 2019-05-07, release date: 2019-10-09, Last modification date: 2024-01-24)

• Primary citation: Valentinis, B.,Porcellini, S.,Asperti, C.,Cota, M.,Zhou, D.,Di Matteo, P.,Garau, G.,Zucchelli, C.,Avanzi, N.R.,Rizzardi, G.P.,Degano, M.,Musco, G.,Traversari, C.; Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling.; Int J Mol Sci, 20:-, 2019; PubMed: 31547231; DOI: 10.3390/ijms20184511

Experimental method

X-RAY DIFFRACTION (2.65 Å)