8B8T
 
 | | Open conformation of the complex of DNA ligase I on PCNA and DNA in the presence of ATP | | 分子名称: | DNA ligase 1, Proliferating cell nuclear antigen | | 著者 | Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. | | 登録日 | 2022-10-05 | | 公開日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
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6EHT
 | | Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme | | 分子名称: | DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ... | | 著者 | De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A. | | 登録日 | 2017-09-15 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
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8YT4
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7QNZ
 | | human Lig1-DNA-PCNA complex reconstituted in absence of ATP | | 分子名称: | ADENOSINE MONOPHOSPHATE, DNA ligase 1, Oligo13P, ... | | 著者 | Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. | | 登録日 | 2021-12-23 | | 公開日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (4.58 Å) | | 主引用文献 | Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
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7QO1
 | | complex of DNA ligase I and FEN1 on PCNA and DNA | | 分子名称: | ADENOSINE MONOPHOSPHATE, DNA ligase 1, Flap endonuclease 1, ... | | 著者 | Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. | | 登録日 | 2021-12-23 | | 公開日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
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6GIS
 | | Structural basis of human clamp sliding on DNA | | 分子名称: | DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen | | 著者 | De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A. | | 登録日 | 2018-05-15 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
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6HVO
 | | Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta | | 分子名称: | DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION | | 著者 | Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A. | | 登録日 | 2018-10-11 | | 公開日 | 2019-01-23 | | 最終更新日 | 2019-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J.Biol.Chem., 294, 2019
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3OP8
 | | Crystal structure of the domain V from beta2-glycoprotein I | | 分子名称: | Beta-2-glycoprotein 1, SULFATE ION | | 著者 | Kolyada, A, Lee, C.-J, De Biasio, A, Beglova, N. | | 登録日 | 2010-08-31 | | 公開日 | 2011-01-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A Novel Dimeric Inhibitor Targeting Beta2GPI in Beta2GPI/Antibody Complexes Implicated in Antiphospholipid Syndrome.
Plos One, 5, 2010
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6GWS
 | | Crystal structure of human PCNA in complex with three p15 peptides | | 分子名称: | PCNA-associated factor, Proliferating cell nuclear antigen | | 著者 | De March, M, Merino, N, Gonzalez-Magana, A, Romano-Moreno, M, Onesti, S, Blanco, F.J, De Biasio, A. | | 登録日 | 2018-06-25 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
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6TNY
 | | Processive human polymerase delta holoenzyme | | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | | 登録日 | 2019-12-10 | | 公開日 | 2019-12-18 | | 最終更新日 | 2020-03-11 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
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7NV1
 | | Human Pol Kappa holoenzyme with Ub-PCNA | | 分子名称: | DNA Primer, DNA Template, DNA polymerase kappa, ... | | 著者 | Lancey, C, De Biasio, A, Hamdan, S.M. | | 登録日 | 2021-03-15 | | 公開日 | 2021-11-03 | | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | | 主引用文献 | Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA.
Nat Commun, 12, 2021
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7NV0
 | | Human Pol Kappa holoenzyme with wt PCNA | | 分子名称: | DNA Primer, DNA Template, DNA polymerase kappa, ... | | 著者 | Lancey, C, De Biasio, A, Hamdan, S.M. | | 登録日 | 2021-03-15 | | 公開日 | 2021-11-10 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA.
Nat Commun, 12, 2021
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6TNZ
 | | Human polymerase delta-FEN1-PCNA toolbelt | | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | | 登録日 | 2019-12-10 | | 公開日 | 2019-12-18 | | 最終更新日 | 2020-03-11 | | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | | 主引用文献 | Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
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6S1O
 | | Human polymerase delta holoenzyme Conformer 3 | | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | | 登録日 | 2019-06-19 | | 公開日 | 2019-12-25 | | 最終更新日 | 2020-03-11 | | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | | 主引用文献 | Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
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6S1M
 | | Human polymerase delta holoenzyme Conformer 1 | | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | | 登録日 | 2019-06-19 | | 公開日 | 2019-12-25 | | 最終更新日 | 2020-03-11 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
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6S1N
 | | Human polymerase delta holoenzyme Conformer 2 | | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | | 登録日 | 2019-06-19 | | 公開日 | 2019-12-25 | | 最終更新日 | 2020-03-11 | | 実験手法 | ELECTRON MICROSCOPY (4.86 Å) | | 主引用文献 | Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
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4D2G
 | | Crystal structure of human PCNA in complex with p15 peptide | | 分子名称: | P15, PROLIFERATING CELL NUCLEAR ANTIGEN | | 著者 | DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J. | | 登録日 | 2014-05-09 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
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4ZTD
 | | Crystal Structure of Human PCNA in complex with a TRAIP peptide | | 分子名称: | ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen | | 著者 | Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A. | | 登録日 | 2015-05-14 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | | 主引用文献 | TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016
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2KRI
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