7D7W
| |
7D82
| |
7D81
| |
7D7Y
| |
7D7V
| |
7D7Z
| |
4UY1
| Novel pyrazole series of group X Secretory Phospholipase A2 (sPLA2-X) inhibitors | 分子名称: | 5-(2,5-DIMETHYL-3-THIENYL)-1H-PYRAZOLE-3-CARBOXAMIDE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Sandmark, J, Oster, L, Hallberg, K, Bodin, C, Chen, H. | 登録日 | 2014-08-28 | 公開日 | 2014-10-15 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of a Novel Pyrazole Series of Group X Secreted Phospholipase A2 Inhibitor (Spla2X) Via Fragment Based Virtual Screening Bioorg.Med.Chem.Lett., 24, 2014
|
|
7T6B
| Structure of S1PR2-heterotrimeric G13 signaling complex | 分子名称: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Li, X, Chen, H. | 登録日 | 2021-12-13 | 公開日 | 2022-04-06 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structure of S1PR2-heterotrimeric G 13 signaling complex. Sci Adv, 8, 2022
|
|
6W36
| Crystal structure of FAM46C | 分子名称: | SULFATE ION, Terminal nucleotidyltransferase 5C | 著者 | Shang, G.J, Zhang, X.W, Chen, H, Lu, D.F. | 登録日 | 2020-03-09 | 公開日 | 2020-05-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.854 Å) | 主引用文献 | Structural and Functional Analyses of the FAM46C/Plk4 Complex. Structure, 28, 2020
|
|
4TOR
| Crystal structure of Tankyrase 1 with IWR-8 | 分子名称: | 1-[(1-acetyl-5-bromo-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(3-methylphenyl)piperidine-4-carboxamide, CHLORIDE ION, Tankyrase-1, ... | 著者 | Chen, H, Zhang, X, Lum, L, Chen, C. | 登録日 | 2014-06-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
|
|
4TOS
| Crystal structure of Tankyrase 1 with 355 | 分子名称: | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide | 著者 | Chen, H, Zhang, X, Lum, l, Chen, C. | 登録日 | 2014-06-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
|
|
6EG5
| The structure of SB-1-202-tubulin complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-chloropyrido[2,3-d]pyrimidin-4-yl)-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one, CALCIUM ION, ... | 著者 | Banerjee, A.K, Wang, Y, Chen, H, Miller, D, Li, W. | 登録日 | 2018-08-18 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The structure of SB-1-202/SB-2-204-tubulin complex To Be Published
|
|
5UI0
| |
5UHN
| |
5UGX
| |
5UGL
| |
4IPX
| Analyzing the visible conformational substates of the FK506 binding protein FKBP12 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Peptidyl-prolyl cis-trans isomerase FKBP1A | 著者 | Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G. | 登録日 | 2013-01-10 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Analysing the visible conformational substates of the FK506-binding protein FKBP12. Biochem.J., 453, 2013
|
|
4J98
| |
6LBC
| shrimp ferritin-T158R | 分子名称: | FE (III) ION, Ferritin | 著者 | Zhao, G, Chen, H, Zhang, T. | 登録日 | 2019-11-14 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions. Food Chem, 349, 2021
|
|
6LBD
| shrimp ferritin T158R G159R | 分子名称: | CHLORIDE ION, FE (III) ION, Ferritin | 著者 | Zhao, G, Chen, H. | 登録日 | 2019-11-14 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.386 Å) | 主引用文献 | Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions. Food Chem, 349, 2021
|
|
1DP7
| COCRYSTAL STRUCTURE OF RFX-DBD IN COMPLEX WITH ITS COGNATE X-BOX BINDING SITE | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*GP*(BRU)P*TP*AP*CP*CP*AP*(BRU)P*GP*GP*TP*AP*AP*CP*G)-3'), ... | 著者 | Gajiwala, K.S, Chen, H, Cornille, F, Roques, B.P, Reith, W, Mach, B, Burley, S.K. | 登録日 | 1999-12-23 | 公開日 | 2000-03-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding. Nature, 403, 2000
|
|
1DT4
| CRYSTAL STRUCTURE OF NOVA-1 KH3 K-HOMOLOGY RNA-BINDING DOMAIN | 分子名称: | NEURO-ONCOLOGICAL VENTRAL ANTIGEN 1 | 著者 | Lewis, H.A, Chen, H, Edo, C, Buckanovich, R.J, Yang, Y.Y.L. | 登録日 | 2000-01-11 | 公開日 | 2000-02-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains. Structure Fold.Des., 7, 1999
|
|
1DTJ
| CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN | 分子名称: | RNA-BINDING NEUROONCOLOGICAL VENTRAL ANTIGEN 2 | 著者 | Lewis, H.A, Chen, H, Edo, C, Buckanovich, R.J, Yang, Y.Y.L, Musunuru, K, Zhong, R, Darnell, R.B, Burley, S.K. | 登録日 | 2000-01-12 | 公開日 | 2000-02-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains. Structure Fold.Des., 7, 1999
|
|
1EC6
| CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN BOUND TO 20-MER RNA HAIRPIN | 分子名称: | 20-MER RNA HAIRPIN, RNA-BINDING PROTEIN NOVA-2 | 著者 | Lewis, H.A, Musunuru, K, Jensen, K.B, Edo, C, Chen, H. | 登録日 | 2000-01-25 | 公開日 | 2000-02-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome. Cell(Cambridge,Mass.), 100, 2000
|
|
1EDU
| CRYSTAL STRUCTURE OF THE ENTH DOMAIN OF RAT EPSIN 1 | 分子名称: | 1,2-ETHANEDIOL, EH domain binding protein EPSIN | 著者 | Hyman, J.H, Chen, H, Decamilli, P, Brunger, A.T. | 登録日 | 2000-01-28 | 公開日 | 2000-05-10 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF). J.Cell Biol., 149, 2000
|
|