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Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E11
分子名称:	1,2-ETHANEDIOL, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ...
著者	Chang, Y, Horton, J.R, Cheng, X.
登録日	2010-04-22
公開日	2010-06-30
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.78 Å)
主引用文献	Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010

3MO5

Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E72
分子名称:	7-[(5-aminopentyl)oxy]-N~4~-[1-(5-aminopentyl)piperidin-4-yl]-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ...
著者	Chang, Y, Horton, J.R, Cheng, X.
登録日	2010-04-22
公開日	2010-06-30
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.14 Å)
主引用文献	Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010

3MO2

human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E67
分子名称:	7-[(5-aminopentyl)oxy]-N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ...
著者	Chang, Y, Horton, J.R, Cheng, X.
登録日	2010-04-22
公開日	2010-06-30
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.49 Å)
主引用文献	Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010

3SW9

GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me0 peptide
分子名称:	DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, SINEFUNGIN, ...
著者	Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日	2011-07-13
公開日	2011-12-07
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (3.05 Å)
主引用文献	MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nat Commun, 2, 2011

3SVM

Human MPP8 - human DNMT3AK47me2 peptide
分子名称:	DNA (cytosine-5)-methyltransferase 3A, M-phase phosphoprotein 8
著者	Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日	2011-07-12
公開日	2011-11-30
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.31 Å)
主引用文献	MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nat Commun, 2, 2011

3SWC

GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me2 peptide
分子名称:	DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者	Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日	2011-07-13
公開日	2011-11-30
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.332 Å)
主引用文献	MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nat Commun, 2, 2011

3OPT

Crystal structure of the Rph1 catalytic core with a-ketoglutarate
分子名称:	2-OXOGLUTARIC ACID, DNA damage-responsive transcriptional repressor RPH1, NICKEL (II) ION
著者	Chang, Y, Wu, J, Tong, X, Zhou, J, Ding, J.
登録日	2010-09-02
公開日	2010-12-22
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism Biochem.J., 433, 2011

3OPW

Crystal Structure of the Rph1 catalytic core
分子名称:	DNA damage-responsive transcriptional repressor RPH1
著者	Chang, Y, Wu, J, Tong, X, Zhou, J, Ding, J.
登録日	2010-09-02
公開日	2010-12-22
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism Biochem.J., 433, 2011

3QO2

Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9
分子名称:	1,2-ETHANEDIOL, Histone H3 peptide, M-phase phosphoprotein 8
著者	Chang, Y, Horton, J.R, Bedford, M.T, Zhang, X, Cheng, X.
登録日	2011-02-09
公開日	2011-04-06
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.49 Å)
主引用文献	Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding. J.Mol.Biol., 408, 2011

3QXY

Human SETD6 in complex with RelA Lys310
分子名称:	1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ...
著者	Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X.
登録日	2011-03-02
公開日	2011-05-25
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.09 Å)
主引用文献	Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling. Nucleic Acids Res., 39, 2011

3FPD

G9a-like protein lysine methyltransferase inhibition by BIX-01294
分子名称:	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine, ...
著者	Chang, Y, Zhang, X, Horton, J.R, Cheng, X.
登録日	2009-01-05
公開日	2009-02-17
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294. Nat.Struct.Mol.Biol., 16, 2009

3RC0

Human SETD6 in complex with RelA Lys310 peptide
分子名称:	1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ...
著者	Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X.
登録日	2011-03-30
公開日	2011-05-25
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.19 Å)
主引用文献	Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling. Nucleic Acids Res., 39, 2011

4PGV

Crystal structure of YetJ from Bacillus Subtilis at pH 8 by back soaking
分子名称:	Uncharacterized protein YetJ
著者	Liu, Q, Chang, Y, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日	2014-05-02
公開日	2014-06-04
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.61 Å)
主引用文献	Structural basis for a pH-sensitive calcium leak across membranes. Science, 344, 2014

4PGW

Crystal structure of YetJ from Bacillus Subtilis at pH 6 by Pt-SAD
分子名称:	PLATINUM (II) ION, Uncharacterized protein YetJ
著者	Liu, Q, Chang, Y, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日	2014-05-02
公開日	2014-06-04
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (3.6 Å)
主引用文献	Structural basis for a pH-sensitive calcium leak across membranes. Science, 344, 2014

4PGS

Crystal structure of YetJ from Bacillus Subtilis at pH 6 by soaking
分子名称:	Uncharacterized protein YetJ
著者	Liu, Q, Chang, Y, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日	2014-05-02
公開日	2014-06-04
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Structural basis for a pH-sensitive calcium leak across membranes. Science, 344, 2014

4PGU

Crystal structure of YetJ from Bacillus Subtilis at pH 7 by soaking
分子名称:	Uncharacterized protein YetJ
著者	Liu, Q, Chang, Y, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日	2014-05-02
公開日	2014-06-04
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (3.401 Å)
主引用文献	Structural basis for a pH-sensitive calcium leak across membranes. Science, 344, 2014

4PGR

Crystal structure of YetJ from Bacillus Subtilis at pH 8
分子名称:	Uncharacterized protein YetJ
著者	Liu, Q, Chang, Y, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日	2014-05-02
公開日	2014-06-04
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Structural basis for a pH-sensitive calcium leak across membranes. Science, 344, 2014

4TKQ

Native-SAD phasing for YetJ from Bacillus Subtilis
分子名称:	CALCIUM ION, CHLORIDE ION, Uncharacterized protein YetJ
著者	Liu, Q, Chang, Y, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日	2014-05-27
公開日	2014-06-18
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.8025 Å)
主引用文献	Multi-crystal native SAD analysis at 6 keV. Acta Crystallogr.,Sect.D, 70, 2014

6NQ8

Crystal structure of YetJ mutant from Bacillus Subtilis - D171E
分子名称:	Uncharacterized protein YetJ
著者	Guo, G, Chang, Y, Liu, Q.
登録日	2019-01-19
公開日	2019-04-17
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Ion and pH Sensitivity of a TMBIM Ca2+Channel. Structure, 27, 2019

6NQ9

Crystal structure of YetJ mutant from Bacillus Subtilis - D195E
分子名称:	Uncharacterized protein YetJ
著者	Guo, G, Chang, Y, Liu, Q.
登録日	2019-01-19
公開日	2019-04-17
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Ion and pH Sensitivity of a TMBIM Ca2+Channel. Structure, 27, 2019

6NQ7

Crystal structure of YetJ from Bacillus Subtilis crystallized in lipidic cubic phase
分子名称:	GADOLINIUM ATOM, Uncharacterized protein YetJ
著者	Guo, G, Chang, Y, Liu, Q.
登録日	2019-01-19
公開日	2019-04-17
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Ion and pH Sensitivity of a TMBIM Ca2+Channel. Structure, 27, 2019

2LJV

Solution structure of Rhodostomin G50L mutant
分子名称:	Disintegrin rhodostomin
著者	Chuang, W, Shiu, J, Chen, C, Chen, Y, Chang, Y, Huang, C.
登録日	2011-09-29
公開日	2012-10-03
最終更新日	2023-06-14
実験手法	SOLUTION NMR
主引用文献	Design of Integrin AlphaVbeta3-Specific Disintegrin for Cancer Therapy To be Published

2M75

The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins
分子名称:	Zinc metalloproteinase/disintegrin
著者	Chuang, W, Chang, Y, Shiu, J.
登録日	2013-04-18
公開日	2013-05-22
実験手法	SOLUTION NMR
主引用文献	The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins To be Published

2M7H

The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrin alpha-IIb beta-3 Recognition
分子名称:	Zinc metalloproteinase/disintegrin
著者	Chuang, W, Chang, Y.
登録日	2013-04-22
公開日	2013-05-22
実験手法	SOLUTION NMR
主引用文献	The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins To be Published

2M7F

The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions
分子名称:	Zinc metalloproteinase/disintegrin
著者	Chuang, W, Chang, Y.
登録日	2013-04-22
公開日	2013-05-22
実験手法	SOLUTION NMR
主引用文献	The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins To be Published

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