1BGW
 
 | | TOPOISOMERASE RESIDUES 410-1202, | | 分子名称: | TOPOISOMERASE | | 著者 | Berger, J.M, Gamblin, S.J, Harrison, S.C, Wang, J.C. | | 登録日 | 1996-02-20 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and mechanism of DNA topoisomerase II.
Nature, 379, 1996
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6DUQ
 | | Structure of a Rho-NusG KOW domain complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Berger, J.M, Lawson, M.R. | | 登録日 | 2018-06-21 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Mechanism for the Regulated Control of Bacterial Transcription Termination by a Universal Adaptor Protein.
Mol. Cell, 71, 2018
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8TXR
 | | E. coli ExoVII(H238A) | | 分子名称: | Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease 7 small subunit | | 著者 | Liu, C, Berger, J.M. | | 登録日 | 2023-08-24 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of Escherichia coli exonuclease VII.
Proc.Natl.Acad.Sci.USA, 121, 2024
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7UGW
 | | M. tuberculosis DNA gyrase cleavage core bound to DNA and evybactin | | 分子名称: | DNA (46-MER), DNA gyrase subunit A, DNA gyrase subunit B, ... | | 著者 | Hauk, G, Imai, Y, Lewis, K, Berger, J.M. | | 登録日 | 2022-03-25 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Evybactin is a DNA gyrase inhibitor that selectively kills Mycobacterium tuberculosis.
Nat.Chem.Biol., 18, 2022
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4WMG
 | | Structure of hen egg-white lysozyme from a microfludic harvesting device using synchrotron radiation (2.5A) | | 分子名称: | Lysozyme C | | 著者 | Lyubimov, A.Y, Murray, T.D, Koehl, A, Uervirojnangkoorn, M, Zeldin, O.B, Cohen, A.E, Soltis, S.M, Baxter, E.M, Brewster, A.S, Sauter, N.K, Brunger, A.T, Berger, J.M. | | 登録日 | 2014-10-08 | | 公開日 | 2015-04-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array.
Acta Crystallogr.,Sect.D, 71, 2015
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1AOL
 | | FRIEND MURINE LEUKEMIA VIRUS RECEPTOR-BINDING DOMAIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GP70, ZINC ION | | 著者 | Fass, D, Davey, R.A, Hamson, C.A, Kim, P.S, Cunningham, J.M, Berger, J.M. | | 登録日 | 1997-07-08 | | 公開日 | 1997-10-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution.
Science, 277, 1997
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1AJJ
 | | LDL RECEPTOR LIGAND-BINDING MODULE 5, CALCIUM-COORDINATING | | 分子名称: | CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, SULFATE ION | | 著者 | Fass, D, Blacklow, S.C, Kim, P.S, Berger, J.M. | | 登録日 | 1997-05-04 | | 公開日 | 1997-07-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module.
Nature, 388, 1997
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1AIK
 | | HIV GP41 CORE STRUCTURE | | 分子名称: | HIV-1 GP41 GLYCOPROTEIN | | 著者 | Chan, D.C, Fass, D, Berger, J.M, Kim, P.S. | | 登録日 | 1997-04-20 | | 公開日 | 1997-06-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Core structure of gp41 from the HIV envelope glycoprotein.
Cell(Cambridge,Mass.), 89, 1997
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1A8V
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1B79
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1BJT
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4TMA
 | | Crystal structure of gyrase bound to its inhibitor YacG | | 分子名称: | DNA gyrase inhibitor YacG, DNA gyrase subunit A, DNA gyrase subunit B, ... | | 著者 | Vos, S.M, Lyubimov, A.Y, Hershey, D.M, Schoeffler, A.J, Berger, J.M. | | 登録日 | 2014-05-31 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Direct control of type IIA topoisomerase activity by a chromosomally encoded regulatory protein.
Genes Dev., 28, 2014
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4TXY
 | | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog | | 分子名称: | Cyclic AMP-GMP synthase, MAGNESIUM ION | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | | 登録日 | 2014-07-07 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.0001 Å) | | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
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4TY0
 | | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG | | 分子名称: | ACETATE ION, Cyclic AMP-GMP synthase, MAGNESIUM ION, ... | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | | 登録日 | 2014-07-07 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
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4TXZ
 | | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP | | 分子名称: | Cyclic AMP-GMP synthase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | | 登録日 | 2014-07-07 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
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6U0X
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS Q123D at cryogenic temperature | | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | 著者 | Jeliazkov, J.R, Robinson, A.C, Berger, J.M, Garcia-Moreno E, B, Gray, J.G. | | 登録日 | 2019-08-15 | | 公開日 | 2019-08-28 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Toward the computational design of protein crystals with improved resolution.
Acta Crystallogr D Struct Biol, 75, 2019
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2G2W
 | | Crystal Structure of the SHV D104K Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex | | 分子名称: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | | 著者 | Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M. | | 登録日 | 2006-02-16 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
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2G2U
 | | Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex | | 分子名称: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | | 著者 | Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M. | | 登録日 | 2006-02-16 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
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6OK8
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS K127L at cryogenic temperature | | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | 著者 | Jeliazkov, J.R, Robinson, A.C, Berger, J.M, Garcia-Moreno E, B, Gray, J.G. | | 登録日 | 2019-04-12 | | 公開日 | 2019-05-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Toward the computational design of protein crystals with improved resolution.
Acta Crystallogr D Struct Biol, 75, 2019
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7MU5
 | | Human DCTPP1 bound to Triptolide | | 分子名称: | MAGNESIUM ION, dCTP pyrophosphatase 1, triptolide | | 著者 | Hauk, G, Berger, J.M. | | 登録日 | 2021-05-14 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1 mediated cell-intrinsic resistance
To Be Published
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4KM5
 | | X-ray crystal structure of human cyclic GMP-AMP synthase (cGAS) | | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Berger, J.M, Doudna, J.A. | | 登録日 | 2013-05-08 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity.
Cell Rep, 3, 2013
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4MN4
 | | Structural Basis for the MukB-topoisomerase IV Interaction | | 分子名称: | Chromosome partition protein MukB, DNA topoisomerase 4 subunit A | | 著者 | Vos, S.M, Stewart, N.K, Oakley, M.G, Berger, J.M. | | 登録日 | 2013-09-09 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the MukB-topoisomerase IV interaction and its functional implications in vivo.
Embo J., 32, 2013
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4NMN
 | | Aquifex aeolicus replicative helicase (DnaB) complexed with ADP, at 3.3 resolution | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Replicative DNA helicase, ... | | 著者 | Lyubimov, A.Y, Strycharska, M.S, Erzberger, J.P, Berger, J.M. | | 登録日 | 2013-11-15 | | 公開日 | 2014-01-29 | | 実験手法 | X-RAY DIFFRACTION (3.301 Å) | | 主引用文献 | Nucleotide and partner-protein control of bacterial replicative helicase structure and function.
Mol.Cell, 52, 2013
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4EDG
 | | The structure of the S. aureus DnaG RNA Polymerase Domain bound to ATP and Manganese | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, BENZAMIDINE, DNA primase, ... | | 著者 | Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. | | 登録日 | 2012-03-27 | | 公開日 | 2012-07-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | | 主引用文献 | Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
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4EE1
 | | The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese | | 分子名称: | BENZAMIDINE, CYTIDINE-5'-TRIPHOSPHATE, DNA primase, ... | | 著者 | Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. | | 登録日 | 2012-03-28 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
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