4EZ9
| Bacillus DNA Polymerase I Large Fragment Complex 2 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-02 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4F2S
| DNA Polymerase I Large Fragment complex 4 | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-08 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4F3O
| DNA Polymerase I Large Fragment Complex 5 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*AP*TP*GP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-09 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4F8R
| Bacillus DNA Polymerase I Large Fragment complex 7 | Descriptor: | DNA (5'-D(*CP*AP*TP*TP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3'), DNA polymerase, ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-17 | Release date: | 2013-08-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4EZ6
| Bacillus DNA Polymerase I Large Fragment Complex 1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-02 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4F4K
| DNA Polymerase I Large Fragment Complex 6 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-10 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
4F2R
| DNA Polymerase I Large Fragment complex 3 | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... | Authors: | Wang, W, Beese, L.S. | Deposit date: | 2012-05-08 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structures of a High-fidelity DNA Polymerase to be published
|
|
2B3B
| Thermus thermophilus Glucose/Galactose Binding Protein With Bound Glucose | Descriptor: | alpha-D-glucopyranose, beta-D-glucopyranose, glucose-binding protein | Authors: | Cuneo, M.J, Changela, A, Warren, J.J, Beese, L.S, Hellinga, H.W. | Deposit date: | 2005-09-20 | Release date: | 2006-07-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites. J.Mol.Biol., 362, 2006
|
|
2B3F
| Thermus thermophilus Glucose/Galactose Binding Protein Bound With Galactose | Descriptor: | beta-D-galactopyranose, glucose-binding protein | Authors: | Cuneo, M.J, Changela, A, Warren, J.J, Beese, L.S, Hellinga, H.W. | Deposit date: | 2005-09-20 | Release date: | 2006-07-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites. J.Mol.Biol., 362, 2006
|
|
1KZP
| PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYLATED K-RAS4B PEPTIDE PRODUCT | Descriptor: | ACETIC ACID, FARNESYL, Farnesylated K-Ras4B peptide product, ... | Authors: | Long, S.B, Casey, P.J, Beese, L.S. | Deposit date: | 2002-02-07 | Release date: | 2002-10-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Reaction path of protein farnesyltransferase at atomic resolution Nature, 419, 2002
|
|
1KZO
| PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYLATED K-RAS4B PEPTIDE PRODUCT AND FARNESYL DIPHOSPHATE SUBSTRATE BOUND SIMULTANEOUSLY | Descriptor: | ACETIC ACID, FARNESYL, FARNESYL DIPHOSPHATE, ... | Authors: | Long, S.B, Casey, P.J, Beese, L.S. | Deposit date: | 2002-02-07 | Release date: | 2002-10-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Reaction Path of Protein Farnesyltransferase at Atomic Resolution Nature, 419, 2002
|
|
1U48
| Extension of a cytosine-8-oxoguanine base pair | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
|
|
1U49
| Adenine-8oxoguanine mismatch at the polymerase active site | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
|
|
1U45
| 8oxoguanine at the pre-insertion site of the polymerase active site | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
|
|
1U4B
| Extension of an adenine-8oxoguanine mismatch | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
|
|
1UA0
| Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase | Descriptor: | 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... | Authors: | Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P, Beese, L.S. | Deposit date: | 2004-08-11 | Release date: | 2004-09-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase J.Biol.Chem., 279, 2004
|
|
1UA1
| Structure of aminofluorene adduct paired opposite cytosine at the polymerase active site. | Descriptor: | 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... | Authors: | Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P, Beese, L.S. | Deposit date: | 2004-08-11 | Release date: | 2004-09-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase J.Biol.Chem., 279, 2004
|
|
1U47
| cytosine-8-Oxoguanine base pair at the polymerase active site | Descriptor: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | Authors: | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | Deposit date: | 2004-07-23 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
|
|
1JCS
| CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE PEPTIDE SUBSTRATE TKCVFM AND AN ANALOG OF FARNESYL DIPHOSPHATE | Descriptor: | ACETIC ACID, PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT, ... | Authors: | Long, S.B, Casey, P.J, Beese, L.S. | Deposit date: | 2001-06-11 | Release date: | 2001-11-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics. Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1JCR
| CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE NON-SUBSTRATE TETRAPEPTIDE INHIBITOR CVFM AND FARNESYL DIPHOSPHATE SUBSTRATE | Descriptor: | ACETIC ACID, FARNESYL DIPHOSPHATE, PROTEIN FARNESYLTRANSFERASE, ... | Authors: | Long, S.B, Casey, P.J, Beese, L.S. | Deposit date: | 2001-06-11 | Release date: | 2001-11-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics. Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1JCQ
| CRYSTAL STRUCTURE OF HUMAN PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYL DIPHOSPHATE AND THE PEPTIDOMIMETIC INHIBITOR L-739,750 | Descriptor: | 2(S)-{2(S)-[2(R)-AMINO-3-MERCAPTO]PROPYLAMINO-3(S)-METHYL}PENTYLOXY-3-PHENYLPROPIONYLMETHIONINE SULFONE, ACETIC ACID, FARNESYL DIPHOSPHATE, ... | Authors: | Long, S.B, Casey, P.J, Beese, L.S. | Deposit date: | 2001-06-11 | Release date: | 2001-11-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics. Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1L3U
| Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 11 base pairs of duplex DNA following addition of a dTTP and a dATP residue. | Descriptor: | 5'-D(*GP*AP*C*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3', DNA Polymerase I, ... | Authors: | Johnson, S.J, Taylor, J.S, Beese, L.S. | Deposit date: | 2002-03-01 | Release date: | 2003-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1L5U
| Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 12 base pairs of duplex DNA following addition of a dTTP, a dATP, and a dCTP residue. | Descriptor: | 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*C)-3', DNA Polymerase I, ... | Authors: | Johnson, S.J, Taylor, J.S, Beese, L.S. | Deposit date: | 2002-03-08 | Release date: | 2003-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1L3S
| Crystal Structure of Bacillus DNA Polymerase I Fragment complexed to 9 base pairs of duplex DNA. | Descriptor: | 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*G)-3', DNA Polymerase I, ... | Authors: | Johnson, S.J, Taylor, J.S, Beese, L.S. | Deposit date: | 2002-03-01 | Release date: | 2003-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1L3V
| Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 15 base pairs of duplex DNA following addition of dTTP, dATP, dCTP, and dGTP residues. | Descriptor: | 5'-D(*GP*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*CP*GP*TP*C)-3', DNA Polymerase I, ... | Authors: | Johnson, S.J, Taylor, J.S, Beese, L.S. | Deposit date: | 2002-03-01 | Release date: | 2003-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
|
|