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7A59
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BU of 7a59 by Molmil
Crimean-Congo Hemorrhagic Fever Virus Envelope Glycoprotein Gc W1191H/W1197A/W1199A Mutant in Postfusion Conformation (Orthorhombic Crystal Form)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Envelopment polyprotein, ...
Authors:Hellert, J, Guardado-Calvo, P, Rey, F.A.
Deposit date:2020-08-20
Release date:2021-10-06
Last modified:2022-04-20
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.
Science, 375, 2022
7NS6
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BU of 7ns6 by Molmil
SARS-CoV-2 Spike (dimers) in complex with six Fu2 nanobodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fu2 nanobody, Spike glycoprotein,Fibritin, ...
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-03-05
Release date:2022-02-02
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Nat Commun, 13, 2022
3RU8
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BU of 3ru8 by Molmil
Structure of an HIV epitope scaffold in complex with neutralizing antibody b12 Fab
Descriptor: Antibody b12, Heavy Chain, Light Chain, ...
Authors:Carrico, C.T.D, Strong, R.K.
Deposit date:2011-05-04
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.
Science, 334, 2011
3RPT
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BU of 3rpt by Molmil
Crystal structure of the anti-HIV b12 scaffold protein
Descriptor: Endoglucanase E-2, SULFATE ION
Authors:Chen, L, Kwong, P.D.
Deposit date:2011-04-27
Release date:2011-12-21
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.303 Å)
Cite:Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.
Science, 334, 2011
7EAM
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BU of 7eam by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 7D6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
Authors:Li, T.T, Gu, Y, Li, S.W.
Deposit date:2021-03-07
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
7EAN
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BU of 7ean by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 6D6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 cross-neutralizing mAb 6D6, Light chain of SARS-CoV-2 cross-neutralizing mAb 6D6, ...
Authors:Li, T.T, Gu, Y, Li, S.W.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
7KMH
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BU of 7kmh by Molmil
LY-CoV488 neutralizing antibody against SARS-CoV-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LY-CoV488 Fab heavy chain, ...
Authors:Hendle, J, Pustilnik, A, Sauder, J.M, Boyles, J.S, Dickinson, C.D, Coleman, K.A.
Deposit date:2020-11-02
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.
Sci Transl Med, 13, 2021
7KMI
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BU of 7kmi by Molmil
LY-CoV481 neutralizing antibody against SARS-CoV-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LY-CoV481 Fab heavy chain, ...
Authors:Hendle, J, Pustilnik, A, Sauder, J.M, Coleman, K.A, Boyles, J.S, Dickinson, C.D.
Deposit date:2020-11-02
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.
Sci Transl Med, 13, 2021
5Y9F
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BU of 5y9f by Molmil
Crystal structure of HPV59 pentamer in complex with the Fab fragment of antibody 28F10
Descriptor: Major capsid protein L1, heavy chain of Fab fragment of antibody 28F10, light chains of Fab fragment of antibody 28F10
Authors:Li, S.W, Li, Z.H.
Deposit date:2017-08-24
Release date:2017-10-25
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
5Y9C
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BU of 5y9c by Molmil
Crystal structure of HPV58 pentamer in complex with the Fab fragment of antibody A12A3
Descriptor: Major capsid protein L1, heavy chain of Fab fragment of antibody A12A3, light chain of Fab fragment of antibody A12A3
Authors:Li, S.W, Li, Z.H.
Deposit date:2017-08-24
Release date:2017-10-25
Method:X-RAY DIFFRACTION (3.443 Å)
Cite:Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
5Y9E
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BU of 5y9e by Molmil
Crystal structure of HPV58 pentamer
Descriptor: GLYCEROL, MAGNESIUM ION, Major capsid protein L1
Authors:Li, S.W, Li, Z.H.
Deposit date:2017-08-24
Release date:2017-10-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.042 Å)
Cite:Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
5W9M
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BU of 5w9m by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9J
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BU of 5w9j by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9P
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BU of 5w9p by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9N
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BU of 5w9n by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, MERS S
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9O
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BU of 5w9o by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9I
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BU of 5w9i by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G4 VH, ...
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9L
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BU of 5w9l by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9H
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BU of 5w9h by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G4 VH, ...
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9K
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BU of 5w9k by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6C6Y
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BU of 6c6y by Molmil
Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque in complex with MERS Receptor Binding Domain
Descriptor: JC57-14 Heavy chain, JC57-14 Light chain, SULFATE ION, ...
Authors:Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
Deposit date:2018-01-19
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
J. Virol., 92, 2018
6C6X
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BU of 6c6x by Molmil
Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque.
Descriptor: JC57-14 Heavy chain, JC57-14 Light chain
Authors:Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
Deposit date:2018-01-19
Release date:2018-02-28
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
J. Virol., 92, 2018

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