1WAY
| Active site thrombin inhibitors | Descriptor: | 4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE, DIMETHYL SULFOXIDE, HIRUGEN, ... | Authors: | Hartshorn, M.J, Murray, C.W, Cleasby, A, Frederickson, M, Tickle, I.J, Jhoti, H. | Deposit date: | 2004-10-28 | Release date: | 2005-01-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Fragment-Based Lead Discovery Using X-Ray Crystallography J.Med.Chem., 48, 2005
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1MID
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1VTT
| GT Wobble Base-Pairing in Z-DNA at 1.0 Angstrom Atomic Resolution: The Crystal Structure of d(CGCGTG) | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*TP*G)-3') | Authors: | Ho, P.S, Frederick, C.A, Quigley, G.J, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J, Rich, A. | Deposit date: | 1988-08-18 | Release date: | 2011-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | GT Wobble Base-Pairing in Z-DNA at 1.0 Angstrom Atomic Resolution: The Crystal Structure of d(CGCGTG) Embo J., 4, 1985
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2G33
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1M5D
| X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J-Y702F) IN COMPLEX WITH Br-HIBO AT 1.73 A RESOLUTION | Descriptor: | (S)-2-AMINO-3-(4-BROMO-3-HYDROXY-ISOXAZOL-5-YL)PROPIONIC ACID, Glutamate receptor 2, SULFATE ION | Authors: | Hogner, A, Kastrup, J.S, Jin, R, Liljefors, T, Mayer, M.L, Egebjerg, J, Larsen, I.K, Gouaux, E. | Deposit date: | 2002-07-09 | Release date: | 2002-09-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural Basis for AMPA Receptor Activation and Ligand Selectivity:
Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding
Core J.Mol.Biol., 322, 2002
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1MN8
| Structure of Moloney Murine Leukaemia Virus Matrix Protein | Descriptor: | Core protein p15 | Authors: | Riffel, N, Harlos, K, Iourin, O, Rao, Z, Kingsman, A, Stuart, D, Fry, E. | Deposit date: | 2002-09-05 | Release date: | 2003-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Atomic resolution structure of Moloney murine leukaemia virus matrix protein and its relationship to other retroviral matrix proteins. Structure, 10, 2002
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1W92
| The structure of carbomonoxy murine neuroglobin reveals a heme- sliding mechanism for affinity regulation | Descriptor: | CARBON MONOXIDE, NEUROGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Vallone, B, Nienhaus, K, Matthes, A, Brunori, M, Nienhaus, G.U. | Deposit date: | 2004-10-05 | Release date: | 2004-11-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Structure of Carbonmonoxy Neuroglobin Reveals a Heme-Sliding Mechanism for Control of Ligand Affinity Proc.Natl.Acad.Sci.USA, 101, 2004
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1LZJ
| Glycosyltransferase B + UDP + H antigen acceptor | Descriptor: | Glycosyltransferase B, MANGANESE (II) ION, MERCURY (II) ION, ... | Authors: | Patenaude, S.I, Seto, N.O.L, Borisova, S.N, Szpacenko, A, Marcus, S.L, Palcic, M.M, Evans, S.V. | Deposit date: | 2002-06-10 | Release date: | 2002-08-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | The structural basis for specificity in human
ABO(H) blood group biosynthesis. Nat.Struct.Biol., 9, 2002
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1WBG
| Active site thrombin inhibitors | Descriptor: | 3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE, DIMETHYL SULFOXIDE, HIRUGEN, ... | Authors: | Hartshorn, M.J, Murray, C.W, Cleasby, A, Frederickson, M, Tickle, I.J, Jhoti, H. | Deposit date: | 2004-11-01 | Release date: | 2005-01-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Fragment-Based Lead Discovery Using X-Ray Crystallography J.Med.Chem., 48, 2005
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8CZP
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8D2P
| Structure of Acidothermus cellulolyticus Cas9 ternary complex (Target bound) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA target strand (5'-D(P*CP*CP*AP*GP*GP*AP*TP*CP*TP*TP*GP*CP*CP*AP*TP*CP*CP*TP*AP*CP*CP*TP*CP*T)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2N
| Structure of Acidothermus cellulolyticus Cas9 ternary complex (Pre-cleavage) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2K
| Structure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 2) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*GP*A)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2O
| Structure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 2) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2L
| Structure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 1) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*GP*A)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.21 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2Q
| Structure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 1) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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1MEX
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1W6H
| Novel plasmepsin II-inhibitor complex | Descriptor: | N-((3S,4S)-5-[(4-BROMOBENZYL)OXY]-3-HYDROXY-4-{[N-(PYRIDIN-2-YLCARBONYL)-L-VALYL]AMINO}PENTANOYL)-L-ALANYL-L-LEUCINAMIDE, PLASMEPSIN 2 | Authors: | Lindberg, J, Johansson, P.-O, Rosenquist, A, Kvarnstroem, I, Vrang, L, Samuelsson, B, Unge, T. | Deposit date: | 2004-08-18 | Release date: | 2006-07-05 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural Study of a Novel Inhibitor with Bulky P1 Side Chain in Complex with Plasmepsin II -Implications for Drug Design To be Published
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1MG7
| Crystal Structure of xol-1 | Descriptor: | early switch protein xol-1 2.2k splice form | Authors: | Luz, J.G, Hassig, C.A, Godzik, A, Meyer, B.J, Wilson, I.A. | Deposit date: | 2002-08-14 | Release date: | 2003-04-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators Genes Dev., 17, 2003
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1MM0
| Solution structure of termicin, an antimicrobial peptide from the termite Pseudacanthotermes spiniger | Descriptor: | Termicin | Authors: | Da Silva, P, Jouvensal, L, Lamberty, M, Bulet, P, Caille, A, Vovelle, F. | Deposit date: | 2002-09-02 | Release date: | 2003-05-13 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of termicin, an antimicrobial peptide from the termite Pseudacanthotermes spiniger PROTEIN SCI., 12, 2003
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8UX9
| Asymmetric unit of the PARIS Immune Complex at 3.2 Angstrom Resolution | Descriptor: | AriA, AriB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Burman, N.B, Henriques, W, Wilkinson, R, Graham, A, Wiedenheft, B. | Deposit date: | 2023-11-09 | Release date: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Activation of the PARIS immune complex results in tRNA cleavage and can be subverted by viral tRNAs To Be Published
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1M0W
| Yeast Glutathione Synthase Bound to gamma-glutamyl-cysteine, AMP-PNP and 2 Magnesium Ions | Descriptor: | GAMMA-GLUTAMYLCYSTEINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Gogos, A, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2002-06-14 | Release date: | 2002-12-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Large Conformational Changes in the Catalytic Cycle of Glutathione Synthase Structure, 10, 2002
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1M3G
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8EBC
| Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Listeria monocytogenes in the complex with IMP | Descriptor: | FORMIC ACID, GLYCEROL, INOSINIC ACID, ... | Authors: | Kim, Y, Maltseva, N, Makowska-Grzyska, M, Osipiuk, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | Deposit date: | 2022-08-31 | Release date: | 2022-09-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Listeria monocytogenes in the complex with IMP To Be Published
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1M5F
| X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J-Y702F) IN COMPLEX WITH ACPA AT 1.95 A RESOLUTION | Descriptor: | (S)-2-AMINO-3-(3-CARBOXY-5-METHYLISOXAZOL-4-YL)PROPIONIC ACID, ACETATE ION, Glutamate receptor 2, ... | Authors: | Hogner, A, Kastrup, J.S, Jin, R, Liljefors, T, Mayer, M.L, Egebjerg, J, Larsen, I.K, Gouaux, E. | Deposit date: | 2002-07-09 | Release date: | 2002-09-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Basis for AMPA Receptor Activation and Ligand Selectivity:
Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding
Core J.Mol.Biol., 322, 2002
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