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5F9W
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BU of 5f9w by Molmil
Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of CH235-lineage antibody CH235, Light chain of CH235-lineage antibody CH235, ...
Authors:Chen, L, Zhou, T, Kwong, P.D.
Deposit date:2015-12-10
Release date:2016-03-09
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (2.8911 Å)
Cite:Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
3MQ0
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BU of 3mq0 by Molmil
Crystal Structure of Agobacterium tumefaciens repressor BlcR
Descriptor: Transcriptional repressor of the blcABC operon
Authors:Chen, L.
Deposit date:2010-04-27
Release date:2011-03-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:The Agrobacterium tumefaciens Transcription Factor BlcR Is Regulated via Oligomerization.
J.Biol.Chem., 286, 2011
7YNK
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BU of 7ynk by Molmil
Structure of human SGLT2-MAP17 complex in the apo state in the inward-facing conformation
Descriptor: PDZK1-interacting protein 1, Sodium/glucose cotransporter 2
Authors:Chen, L, Niu, Y.
Deposit date:2022-07-31
Release date:2023-05-31
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
7YNJ
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BU of 7ynj by Molmil
Structure of human SGLT2-MAP17 complex bound with substrate AMG in the occluded conformation
Descriptor: PDZK1-interacting protein 1, Sodium/glucose cotransporter 2, methyl alpha-D-glucopyranoside
Authors:Chen, L, Niu, Y, Cui, W.
Deposit date:2022-07-31
Release date:2023-05-31
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
7YNI
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BU of 7yni by Molmil
Structure of human SGLT1-MAP17 complex bound with substrate 4D4FDG in the occluded conformation
Descriptor: (2R,3R,4R,5S,6R)-5-fluoranyl-6-(hydroxymethyl)oxane-2,3,4-triol, PDZK1-interacting protein 1, Sodium/glucose cotransporter 1
Authors:Chen, L, Niu, Y, Cui, W.
Deposit date:2022-07-31
Release date:2023-05-31
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
9IYX
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BU of 9iyx by Molmil
Structure of HBV surface antigen determined in recombinant spherical subviral particle
Descriptor: Large envelope protein, ZINC ION
Authors:Chen, L, He, X.
Deposit date:2024-07-31
Release date:2025-01-15
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of small HBV surface antigen reveals mechanism of dimer formation.
Cell Discov, 11, 2025
1AAN
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BU of 1aan by Molmil
CRYSTAL STRUCTURE ANALYSIS OF AMICYANIN AND APOAMICYANIN FROM PARACOCCUS DENITRIFICANS AT 2.0 ANGSTROMS AND 1.8 ANGSTROMS RESOLUTION
Descriptor: AMICYANIN, COPPER (II) ION
Authors:Chen, L, Durley, R.C.E, Lim, L.W, Mathews, F.S.
Deposit date:1992-04-09
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure analysis of amicyanin and apoamicyanin from Paracoccus denitrificans at 2.0 A and 1.8 A resolution.
Protein Sci., 2, 1993
9IYY
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BU of 9iyy by Molmil
Structure of HBsAg in complex with Fab H006
Descriptor: Large envelope protein, heavy chain of antibody H006 Fab, light chain of antibody H006 Fab
Authors:Chen, L, He, X.
Deposit date:2024-07-31
Release date:2025-07-02
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural polymorphism of the antigenic loop in HBV surface antigen dictates binding of diverse neutralizing antibodies.
Cell Discov, 11, 2025
2LOZ
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BU of 2loz by Molmil
The novel binding mode of DLC1 and Tensin2 PTB domain
Descriptor: Rho GTPase-activating protein 7, Tensin-like C1 domain-containing phosphatase
Authors:Liu, C, Chen, L, Zhu, G.
Deposit date:2012-01-29
Release date:2012-06-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode.
J.Biol.Chem., 287, 2012
4U1W
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BU of 4u1w by Molmil
Full length GluA2-kainate-(R,R)-2b complex crystal form A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U1X
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BU of 4u1x by Molmil
Full length GluA2-kainate-(R,R)-2b complex crystal form B
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U1Z
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BU of 4u1z by Molmil
GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form D
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9401 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4CIK
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BU of 4cik by Molmil
plasminogen kringle 1 in complex with inhibitor
Descriptor: 5-[(2R,4S)-2-(phenylmethyl)piperidin-4-yl]-1,2-oxazol-3-one, PLASMINOGEN
Authors:Xue, Y, Johansson, C, Cheng, L, Pettersen, D, Gustafsson, D.
Deposit date:2013-12-10
Release date:2014-06-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Discovery of the Fibrinolysis Inhibitor Azd6564, Acting Via Interference of a Protein-Protein Interaction.
Acs Med.Chem.Lett., 5, 2014
3BWH
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BU of 3bwh by Molmil
Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, L.
Deposit date:2008-01-09
Release date:2008-10-07
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1 Å)
Cite:Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata.
J.Struct.Biol., 164, 2008
3HI1
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BU of 3hi1 by Molmil
Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, F105 Heavy Chain, F105 Light Chain, ...
Authors:Kwon, Y.D, Chen, L, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z, Zhang, M.-Y, Arthos, J, Burton, D.R, Dimitrov, D, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D.
Deposit date:2009-05-18
Release date:2009-11-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
5TDL
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BU of 5tdl by Molmil
Crystal structure of prefusion-stabilized bovine RSV fusion glycoprotein (single-chain DS2-v1 variant: strain 391-2 sc9 DS-Cav1 Q98C Q361C)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bovine prefusion RSV F glycoprotein
Authors:Chen, L, Zhang, B, Kwong, P.D.
Deposit date:2016-09-19
Release date:2017-08-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Protection of calves by a prefusion-stabilized bovine RSV F vaccine.
NPJ Vaccines, 2, 2017
5TDG
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BU of 5tdg by Molmil
Crystal structure of prefusion-stabilized bovine RSV F (DS-Cav1 variant: strain ATue51908)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0,Fibritin
Authors:Chen, L, Zhang, B, Kwong, P.D.
Deposit date:2016-09-19
Release date:2017-08-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Protection of calves by a prefusion-stabilized bovine RSV F vaccine.
NPJ Vaccines, 2, 2017
8WEJ
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BU of 8wej by Molmil
Structure of human phagocyte NADPH oxidase in the activated state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
Authors:Chen, L, Liu, X.
Deposit date:2023-09-18
Release date:2024-01-24
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024
8GZ3
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BU of 8gz3 by Molmil
Structure of human phagocyte NADPH oxidase in the resting state
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, ...
Authors:Chen, L, Liu, R.
Deposit date:2022-09-24
Release date:2022-12-21
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of human phagocyte NADPH oxidase in the resting state.
Elife, 11, 2022
8X2L
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BU of 8x2l by Molmil
Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
Authors:Chen, L, Liu, X.
Deposit date:2023-11-09
Release date:2024-01-24
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024
3DAE
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BU of 3dae by Molmil
Crystal structure of phosphorylated SNF1 kinase domain
Descriptor: Carbon catabolite-derepressing protein kinase
Authors:Zheng, L.-S, Chen, L, Jiao, Z.-H, Wu, J.-W.
Deposit date:2008-05-29
Release date:2009-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
Nature, 459, 2009
7L7S
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BU of 7l7s by Molmil
Human mitochondrial chaperonin mHsp60
Descriptor: 60 kDa heat shock protein, mitochondrial
Authors:Chen, L, Wang, J.C.Y.
Deposit date:2020-12-30
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60.
Sci Rep, 11, 2021
8HBF
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BU of 8hbf by Molmil
Structure of human soluble guanylate cyclase in the NO+Rio state at 3.1 angstrom
Descriptor: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, MAGNESIUM ION, ...
Authors:Chen, L, Liu, R.
Deposit date:2022-10-28
Release date:2023-04-19
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.
Nitric Oxide, 134-135, 2023
8HBE
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BU of 8hbe by Molmil
Structure of human soluble guanylate cyclase in the inactive state at 3.1 angstrom
Descriptor: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Chen, L, Liu, R.
Deposit date:2022-10-28
Release date:2023-04-19
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.
Nitric Oxide, 134-135, 2023
8HBH
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BU of 8hbh by Molmil
Structure of human soluble guanylate cyclase in the NO-activated state at 3.1 angstrom
Descriptor: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, MAGNESIUM ION, ...
Authors:Chen, L, Liu, R.
Deposit date:2022-10-28
Release date:2023-04-19
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.
Nitric Oxide, 134-135, 2023

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