2LOZ

The novel binding mode of DLC1 and Tensin2 PTB domain

Summary for 2LOZ

• Entry DOI: 10.2210/pdb2loz/pdb
• NMR Information: BMRB: 17364
• Descriptor: Tensin-like C1 domain-containing phosphatase, Rho GTPase-activating protein 7 (2 entities in total)
• Functional Keywords: ptb, dlc1, hydrolase-hydrolase activator complex, hydrolase/hydrolase activator
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 17540.86

Authors

Liu, C.,Chen, L.,Zhu, G. (deposition date: 2012-01-29, release date: 2012-06-06, Last modification date: 2023-06-14)

• Primary citation: Chen, L.,Liu, C.,Ko, F.C.,Xu, N.,Ng, I.O.,Yam, J.W.,Zhu, G.; Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode.; J.Biol.Chem., 287:26104-26114, 2012; PubMed: 22645138; DOI: 10.1074/jbc.M112.360206

Experimental method

SOLUTION NMR