1MFR
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![BU of 1mfr by Molmil](/molmil-images/mine/1mfr) | CRYSTAL STRUCTURE OF M FERRITIN | Descriptor: | M FERRITIN, MAGNESIUM ION | Authors: | Ha, Y, Shi, D, Allewell, N.M. | Deposit date: | 1998-06-18 | Release date: | 1999-06-22 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of bullfrog M ferritin at 2.8 A resolution: analysis of subunit interactions and the binuclear metal center J.Biol.Inorg.Chem., 4, 1999
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5LGG
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![BU of 5lgg by Molmil](/molmil-images/mine/5lgg) | The N-terminal WD40 domain of Apc1 (Anaphase promoting complex subunit 1) | Descriptor: | Anaphase-promoting complex subunit 1,Anaphase-promoting complex subunit 1,Anaphase-promoting complex subunit 1,Anaphase-promoting complex subunit 1 | Authors: | Li, Q, Aibara, S, Barford, D. | Deposit date: | 2016-07-07 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | WD40 domain of Apc1 is critical for the coactivator-induced allosteric transition that stimulates APC/C catalytic activity. Proc.Natl.Acad.Sci.USA, 113, 2016
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5LD5
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![BU of 5ld5 by Molmil](/molmil-images/mine/5ld5) | Crystal structure of a bacterial dehydrogenase at 2.19 Angstroms resolution | Descriptor: | GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Querol-Garcia, J, Fernandez, F.J, Gomez, S, Fulla, D, Juanhuix, J, Vega, M.C. | Deposit date: | 2016-06-23 | Release date: | 2017-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1906 Å) | Cite: | Crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from the Gram-Positive Bacterial Pathogen A. vaginae, an Immunoevasive Factor that Interacts with the Human C5a Anaphylatoxin. Front Microbiol, 8, 2017
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2VIO
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![BU of 2vio by Molmil](/molmil-images/mine/2vio) | Fragment-Based Discovery of Mexiletine Derivatives as Orally Bioavailable Inhibitors of Urokinase-Type Plasminogen Activator | Descriptor: | 4-(2-aminoethoxy)-3,5-dichlorobenzoic acid, ACETATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR CHAIN B | Authors: | Frederickson, M, Callaghan, O, Chessari, G, Congreve, M, Cowan, S.R, Matthews, J.E, McMenamin, R, Smith, D, Vinkovic, M, Wallis, N.G. | Deposit date: | 2007-12-05 | Release date: | 2008-01-22 | Last modified: | 2017-07-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fragment-Based Discovery of Mexiletine Derivatives as Orally Bioavailable Inhibitors of Urokinase-Type Plasminogen Activator J.Med.Chem., 51, 2008
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5LI8
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![BU of 5li8 by Molmil](/molmil-images/mine/5li8) | Crystal structure of Mycobacterium tuberculosis CYP126A1 in complex with ketoconazole | Descriptor: | 1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 126 | Authors: | Levy, C, Munro, A.W, Leys, D. | Deposit date: | 2016-07-14 | Release date: | 2016-12-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1. J. Biol. Chem., 292, 2017
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1TN5
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![BU of 1tn5 by Molmil](/molmil-images/mine/1tn5) | Structure of bacterorhodopsin mutant K41P | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Yohannan, S, Yang, D, Faham, S, Boulting, G, Whitelegge, J, Bowie, J.U. | Deposit date: | 2004-06-11 | Release date: | 2004-10-19 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Proline substitutions are not easily accommodated in a membrane protein J.Mol.Biol., 341, 2004
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2VAL
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![BU of 2val by Molmil](/molmil-images/mine/2val) | Crystal structure of an Escherichia coli tRNAGly microhelix at 2.0 Angstrom resolution | Descriptor: | 5'-R(*GP*CP*GP*GP*GP*AP*AP)-3', 5'-R(*UP*UP*CP*CP*CP*GP*CP)-3', MAGNESIUM ION | Authors: | Forster, C, Brauer, A.B.E, Perbandt, M, Lehmann, D, Furste, J.P, Betzel, C, Erdmann, V.A. | Deposit date: | 2007-09-03 | Release date: | 2007-10-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of an Escherichia Coli Trnagly Microhelix at 2.0 Angstrom Resolution Biochem.Biophys.Res.Commun., 363, 2007
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2V1S
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![BU of 2v1s by Molmil](/molmil-images/mine/2v1s) | CRYSTAL STRUCTURE OF RAT TOM20-ALDH PRESEQUENCE COMPLEX | Descriptor: | ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG | Authors: | Obita, T, Igura, M, Ose, T, Endo, T, Maenaka, K, Kohda, D. | Deposit date: | 2007-05-29 | Release date: | 2007-06-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Tom20 Recognizes Mitochondrial Presequences Through Dynamic Equilibrium Among Multiple Bound States. Embo J., 26, 2007
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5LKR
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![BU of 5lkr by Molmil](/molmil-images/mine/5lkr) | Human Butyrylcholinesterase complexed with N-Propargyliperidines | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cholinesterase, ... | Authors: | Coquelle, N, Knez, D, Colletier, J.P, Gobec, S. | Deposit date: | 2016-07-23 | Release date: | 2016-12-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents. Bioorg. Med. Chem., 25, 2017
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1M5S
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![BU of 1m5s by Molmil](/molmil-images/mine/1m5s) | Formylmethanofuran:tetrahydromethanopterin fromyltransferase from Methanosarcina barkeri | Descriptor: | Formylmethanofuran--tetrahydromethanopterin formyltransferase | Authors: | Mamat, B, Roth, A, Grimm, C, Ermler, U, Tziatzios, C, Schubert, D, Thauer, R.K, Shima, S. | Deposit date: | 2002-07-10 | Release date: | 2002-07-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures and enzymatic properties of three formyltransferases from archaea: environmental adaptation and evolutionary relationship. Protein Sci., 11, 2002
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1M8A
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![BU of 1m8a by Molmil](/molmil-images/mine/1m8a) | Human MIP-3alpha/CCL20 | Descriptor: | ISOPROPYL ALCOHOL, Small inducible cytokine A20 | Authors: | Hoover, D.M, Boulegue, C, Yang, D, Oppenheim, J.J, Tucker, K, Lu, W, Lubkowski, J. | Deposit date: | 2002-07-24 | Release date: | 2002-07-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins J.Biol.Chem., 277, 2002
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2VIT
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![BU of 2vit by Molmil](/molmil-images/mine/2vit) | INFLUENZA VIRUS HEMAGGLUTININ, MUTANT WITH THR 155 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY | Descriptor: | HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ... | Authors: | Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M. | Deposit date: | 1997-12-22 | Release date: | 1998-04-29 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Antigen distortion allows influenza virus to escape neutralization. Nat.Struct.Biol., 5, 1998
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2V7V
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![BU of 2v7v by Molmil](/molmil-images/mine/2v7v) | |
2V7W
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2VLO
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![BU of 2vlo by Molmil](/molmil-images/mine/2vlo) | K97A mutant of E9 DNase domain in complex with Im9 | Descriptor: | COLICIN E9, COLICIN-E9 IMMUNITY PROTEIN, SULFATE ION | Authors: | Keeble, A.H, Joachimiak, L.A, Mate, M.J, Meenan, N, Kirkpatrick, N, Baker, D, Kleanthous, C. | Deposit date: | 2008-01-15 | Release date: | 2008-05-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases. J.Mol.Biol., 379, 2008
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7LNM
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![BU of 7lnm by Molmil](/molmil-images/mine/7lnm) | Ornithine Aminotransferase (OAT) cocrystallized with its inactivator - (1S,3S)-3-amino-4-(difluoromethylene)cyclopentene-1-carboxylic acid | Descriptor: | (1~{R},3~{S},4~{R})-3-methyl-4-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]cyclopentane-1-carboxylic acid, Ornithine aminotransferase, mitochondrial | Authors: | Butrin, A, Catlin, D, Zhu, W, Liu, D, Silverman, R. | Deposit date: | 2021-02-07 | Release date: | 2021-08-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Remarkable and Unexpected Mechanism for ( S )-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase. J.Am.Chem.Soc., 143, 2021
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5LRV
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![BU of 5lrv by Molmil](/molmil-images/mine/5lrv) | Structure of Cezanne/OTUD7B OTU domain bound to Lys11-linked diubiquitin | Descriptor: | GLYCEROL, OTU domain-containing protein 7B, PHOSPHATE ION, ... | Authors: | Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D. | Deposit date: | 2016-08-22 | Release date: | 2016-10-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538, 2016
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2VKR
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![BU of 2vkr by Molmil](/molmil-images/mine/2vkr) | 3Fe-4S, 4Fe-4S plus Zn Acidianus ambivalens ferredoxin | Descriptor: | FE3-S4 CLUSTER, IRON/SULFUR CLUSTER, ZINC ION, ... | Authors: | Frazao, C, Aragao, D, Coelho, R, Leal, S.S, Gomes, C.M, Teixeira, M, Carrondo, M.A. | Deposit date: | 2007-12-23 | Release date: | 2008-03-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystallographic analysis of the intact metal centres [3Fe-4S](1+/0) and [4Fe-4S](2+/1+) in a Zn(2+) -containing ferredoxin. FEBS Lett., 582, 2008
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1TN0
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![BU of 1tn0 by Molmil](/molmil-images/mine/1tn0) | Structure of bacterorhodopsin mutant A51P | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Yohannan, S, Yang, D, Faham, S, Boulting, G, Whitelegge, J, Bowie, J.U. | Deposit date: | 2004-06-11 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Proline substitutions are not easily accommodated in a membrane protein J.Mol.Biol., 341, 2004
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5M1E
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![BU of 5m1e by Molmil](/molmil-images/mine/5m1e) | Crystal structure of N-terminally tagged UbiD from E. coli reconstituted with prFMN cofactor | Descriptor: | (16~{R})-11,12,14,14-tetramethyl-3,5-bis(oxidanylidene)-8-[(2~{S},3~{S},4~{R})-2,3,4-tris(oxidanyl)-5-phosphonooxy-pentyl]-1,4,6,8-tetrazatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-2(7),9(17),10,12-tetraene-16-sulfonic acid, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, MANGANESE (II) ION, ... | Authors: | Marshall, S.A, Leys, D. | Deposit date: | 2016-10-07 | Release date: | 2017-01-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Oxidative Maturation and Structural Characterization of Prenylated FMN Binding by UbiD, a Decarboxylase Involved in Bacterial Ubiquinone Biosynthesis. J. Biol. Chem., 292, 2017
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2VB5
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![BU of 2vb5 by Molmil](/molmil-images/mine/2vb5) | Solution structure of W60G mutant of human beta2-microglobulin | Descriptor: | BETA-2-MICROGLOBULIN | Authors: | Esposito, G, Corazza, A, Rennella, E, Gumral, D, Mimmi, M.C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M, Bellotti, V. | Deposit date: | 2007-09-06 | Release date: | 2007-09-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Controlling Roles of Trp60 and Trp95 in Beta2-Microglobulin Function, Folding and Amyloid Aggregation Properties. J.Mol.Biol., 378, 2008
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1MFK
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![BU of 1mfk by Molmil](/molmil-images/mine/1mfk) | Structure of Prokaryotic SECIS mRNA Hairpin | Descriptor: | 5'-R(P*GP*GP*CP*GP*GP*UP*UP*GP*CP*AP*GP*GP*UP*CP*UP*GP*CP*AP*CP*CP*GP*CP*C)-3' | Authors: | Fourmy, D, Guittet, E, Yoshizawa, S. | Deposit date: | 2002-08-12 | Release date: | 2002-11-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of Prokaryotic SECIS mRNA Hairpin and its Interaction with Elongation Factor SELB J.Mol.Biol., 324, 2002
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1TR7
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![BU of 1tr7 by Molmil](/molmil-images/mine/1tr7) | FimH adhesin receptor binding domain from uropathogenic E. coli | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, FimH protein, ... | Authors: | Bouckaert, J, Berglund, J, Schembri, M, De Genst, E, Cools, L, Wuhrer, M, Hung, C.S, Pinkner, J, Slattegard, R, Zavialov, A, Choudhury, D, Langermann, S, Hultgren, S.J, Wyns, L, Klemm, P, Oscarson, S, Knight, S.D, De Greve, H. | Deposit date: | 2004-06-21 | Release date: | 2005-05-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin Mol.Microbiol., 55, 2005
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5LT7
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![BU of 5lt7 by Molmil](/molmil-images/mine/5lt7) | Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives | Descriptor: | Histone-lysine N-methyltransferase SETD2, THIOCYANATE ION, ZINC ION, ... | Authors: | Tisi, D, Pathuri, P, Heightman, T. | Deposit date: | 2016-09-06 | Release date: | 2016-10-05 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives. ACS Chem. Biol., 11, 2016
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2VD6
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![BU of 2vd6 by Molmil](/molmil-images/mine/2vd6) | Human adenylosuccinate lyase in complex with its substrate N6-(1,2- Dicarboxyethyl)-AMP, and its products AMP and fumarate. | Descriptor: | 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID, ADENOSINE MONOPHOSPHATE, ADENYLOSUCCINATE LYASE, ... | Authors: | Stenmark, P, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Welin, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-30 | Release date: | 2007-10-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human Adenylosuccinate Lyase in Complex with its Substrate N6-(1,2-Dicarboxyethyl)-AMP, and its Products AMP and Fumarate. To be Published
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