2R6M
 
 | | Crystal structure of rat CK2-beta subunit | | Descriptor: | Casein kinase II subunit beta, ZINC ION | | Authors: | Shen, Y. | | Deposit date: | 2007-09-06 | | Release date: | 2008-09-23 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2
CHIN.SCI.BULL., 54, 2009
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3IKA
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8CYI
 | | Cryo-EM structures and computational analysis for enhanced potency in MTA-synergic inhibition of human protein arginine methyltransferase 5 | | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methylosome protein 50, N-[(2-aminoquinolin-7-yl)methyl]-9-(2-hydroxyethyl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide, ... | | Authors: | Yadav, G.P, Wei, Z, Xiaozhi, Y, Chenglong, L, Jiang, Q. | | Deposit date: | 2022-05-23 | | Release date: | 2023-04-12 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Cryo-EM structure-based selection of computed ligand poses enables design of MTA-synergic PRMT5 inhibitors of better potency.
Commun Biol, 5, 2022
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4U95
 | | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB | | Descriptor: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, DARPin, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Pos, K.M. | | Deposit date: | 2014-08-05 | | Release date: | 2014-10-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB
eLife, 3, 2014
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1SQS
 | | X-Ray Crystal Structure Protein SP1951 of Streptococcus pneumoniae. Northeast Structural Genomics Consortium Target SpR27. | | Descriptor: | L(+)-TARTARIC ACID, conserved hypothetical protein | | Authors: | Forouhar, F, Lee, I, Vorobiev, S.M, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-03-19 | | Release date: | 2004-03-30 | | Last modified: | 2017-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Functional insights from structural genomics.
J.STRUCT.FUNCT.GENOM, 8, 2007
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3LXD
 | | Crystal Structure of Ferredoxin Reductase ArR from Novosphingobium aromaticivorans | | Descriptor: | FAD-dependent pyridine nucleotide-disulphide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Yang, W, Bell, S.G, Wang, H, Bartlam, M, Wong, L.L, Rao, Z. | | Deposit date: | 2010-02-25 | | Release date: | 2010-06-23 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444
J.Biol.Chem., 285, 2010
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3NV6
 | | Crystal Structure of Camphor-Bound CYP101D2 | | Descriptor: | CAMPHOR, Cytochrome P450, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Yang, W, Bell, S.G, Wang, H, Zhou, W.H, Bartlam, M, Wong, L.L, Rao, Z. | | Deposit date: | 2010-07-08 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structure of CYP101D2 unveils a potential path for substrate entry into the active site
Biochem.J., 433, 2011
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3NV5
 | | Crystal Structure of Cytochrome P450 CYP101D2 | | Descriptor: | Cytochrome P450, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Yang, W, Bell, S.G, Wang, H, Zhou, W.H, Bartlam, M, Wong, L.L, Rao, Z. | | Deposit date: | 2010-07-08 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | The structure of CYP101D2 unveils a potential path for substrate entry into the active site
Biochem.J., 433, 2011
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6B5Q
 | | DCN1 bound to 38 | | Descriptor: | DCN1-like protein 1, Peptidomimetic Inhibitors DI-591, TRIETHYLENE GLYCOL | | Authors: | Stuckey, J. | | Deposit date: | 2017-09-29 | | Release date: | 2018-02-28 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction.
J. Med. Chem., 61, 2018
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4WO6
 | | Lysozyme Pre-surface acoustic wave | | Descriptor: | Lysozyme C, SODIUM ION | | Authors: | French, J.B. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WOA
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4WOB
 | | Proteinase-K Pre-Surface Acoustic Wave | | Descriptor: | Proteinase K, SULFATE ION | | Authors: | French, J.B. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WV5
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3E3R
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5UFI
 | | DCN1 bound to DI-591 | | Descriptor: | DCN1-like protein 1, N-[(1S)-1-cyclohexyl-2-{[3-(morpholin-4-yl)propanoyl]amino}ethyl]-N~2~-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alaninamide | | Authors: | Stuckey, J. | | Deposit date: | 2017-01-04 | | Release date: | 2017-11-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation.
Nat Commun, 8, 2017
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3SV1
 | | Crystal structure of APP peptide bound rat Mint2 PARM | | Descriptor: | Amyloid beta A4 precursor protein-binding family A member 2, Amyloid beta A4 protein | | Authors: | Shen, Y, Long, J, Yan, X, Xie, X. | | Deposit date: | 2011-07-12 | | Release date: | 2012-07-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Open-closed motion of Mint2 regulates APP metabolism
J Mol Cell Biol, 5, 2013
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3SUZ
 | | Crystal structure of Rat Mint2 PPC | | Descriptor: | Amyloid beta A4 precursor protein-binding family A member 2 | | Authors: | Shen, Y, Long, J, Yan, X, Xie, X. | | Deposit date: | 2011-07-11 | | Release date: | 2012-07-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Open-closed motion of Mint2 regulates APP metabolism
J Mol Cell Biol, 5, 2013
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5H9T
 | | Crystal structure of native NalD at resolution of 2.9, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa | | Descriptor: | NalD | | Authors: | Chen, W.Z, Wang, D, Huang, S.Q, Hu, Q.Y, Liu, X.C, Gan, J.H, Chen, H. | | Deposit date: | 2015-12-29 | | Release date: | 2016-04-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosa.
Mol. Microbiol., 100, 2016
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7S4E
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5JJA
 | | Crystal structure of a PP2A B56gamma/BubR1 complex | | Descriptor: | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | | Authors: | Wang, Z, Wang, J, Rao, Z, Xu, W. | | Deposit date: | 2016-04-22 | | Release date: | 2016-07-13 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization.
Protein Cell, 7, 2016
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4WOC
 | | Proteinase-K Post-Surface Acoustic Waves | | Descriptor: | Proteinase K, SULFATE ION | | Authors: | French, J.B. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WO9
 | | Lysozyme Post-Surface Acoustic Waves | | Descriptor: | Lysozyme C, SODIUM ION | | Authors: | French, J.B. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WV7
 | | HEAT SHOCK PROTEIN 70 SUBSTRATE BINDING DOMAIN WITH COVALENTLY LINKED NOVOLACTONE | | Descriptor: | (5beta,6alpha,8alpha,14alpha)-13-ethenyl-5,6-dihydroxy-14-methylpodocarp-12-en-15-oic acid, Heat shock 70 kDa protein 1A/1B | | Authors: | Kirby, C.A, Baird, J, Stams, T. | | Deposit date: | 2014-11-04 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | The novolactone natural product disrupts the allosteric regulation of hsp70.
Chem.Biol., 22, 2015
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4U8V
 | | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB | | Descriptor: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, DARPin, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Pos, K.M. | | Deposit date: | 2014-08-04 | | Release date: | 2014-10-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.298 Å) | | Cite: | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB.
Elife, 3, 2014
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4U96
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