5HL9
 
 | | E. coli PBP1b in complex with acyl-ampicillin and moenomycin | | Descriptor: | (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, MOENOMYCIN, Penicillin-binding protein 1B | | Authors: | King, D.T, Strynadka, N.C.J. | | Deposit date: | 2016-01-14 | | Release date: | 2016-12-14 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Insights into Inhibition of Escherichia coli Penicillin-binding Protein 1B.
J.Biol.Chem., 292, 2017
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1JHE
 | | LEXA L89P Q92W E152A K156A MUTANT | | Descriptor: | LEXA REPRESSOR | | Authors: | Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, J Strynadka, N.C. | | Deposit date: | 2001-06-27 | | Release date: | 2001-09-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of LexA: a conformational switch for regulation of self-cleavage.
Cell(Cambridge,Mass.), 106, 2001
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2P56
 | | Crystal structure of alpha-2,3-sialyltransferase from Campylobacter jejuni in apo form | | Descriptor: | 1,2-ETHANEDIOL, Alpha-2,3-sialyltransferase | | Authors: | Chiu, C.P, Lairson, L.L, Gilbert, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C. | | Deposit date: | 2007-03-14 | | Release date: | 2007-07-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Analysis of the alpha-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms.
Biochemistry, 46, 2007
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2O4V
 | | An arginine ladder in OprP mediates phosphate specific transfer across the outer membrane | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Moraes, T.F, Bains, M, Hancock, R.E, Strynadka, N.C. | | Deposit date: | 2006-12-05 | | Release date: | 2006-12-26 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | An arginine ladder in OprP mediates phosphate-specific transfer across the outer membrane.
Nat.Struct.Mol.Biol., 14, 2007
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2OLU
 | | Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme | | Descriptor: | 1,2-ETHANEDIOL, Penicillin-binding protein 2 | | Authors: | Lovering, A.L, De Castro, L.H, Lim, D, Strynadka, N.C. | | Deposit date: | 2007-01-19 | | Release date: | 2007-03-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis.
Science, 315, 2007
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2P2V
 | | Crystal structure analysis of monofunctional alpha-2,3-sialyltransferase Cst-I from Campylobacter jejuni | | Descriptor: | 1,2-ETHANEDIOL, Alpha-2,3-sialyltransferase, CHLORIDE ION, ... | | Authors: | Chiu, C.P, Lairson, L.L, Gilbert, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C. | | Deposit date: | 2007-03-07 | | Release date: | 2007-07-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural Analysis of the alpha-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms.
Biochemistry, 46, 2007
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2OSY
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2OYM
 | | Endo-glycoceramidase II from Rhodococcus sp.: five-membered iminocyclitol complex | | Descriptor: | Endoglycoceramidase II, N-{[(2R,3R,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PYRROLIDIN-2-YL]METHYL}-4-(DIMETHYLAMINO)BENZAMIDE, SODIUM ION | | Authors: | Caines, M.E.C, Strynadka, N.C.J. | | Deposit date: | 2007-02-22 | | Release date: | 2007-03-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.
Angew.Chem.Int.Ed.Engl., 46, 2007
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2OYK
 | | Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like isofagomine complex | | Descriptor: | (3R,4R,5R)-3-hydroxy-5-(hydroxymethyl)piperidin-4-yl beta-D-glucopyranoside, Endoglycoceramidase II, GLYCEROL, ... | | Authors: | Caines, M.E.C, Strynadka, N.C.J. | | Deposit date: | 2007-02-22 | | Release date: | 2007-03-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.
Angew.Chem.Int.Ed.Engl., 46, 2007
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2OSX
 | | Endo-glycoceramidase II from Rhodococcus sp.: Ganglioside GM3 Complex | | Descriptor: | Endoglycoceramidase II, GLYCEROL, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, ... | | Authors: | Caines, M.E.C, Strynadka, N.C.J. | | Deposit date: | 2007-02-06 | | Release date: | 2007-02-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Structural and Mechanistic Analyses of endo-Glycoceramidase II, a Membrane-associated Family 5 Glycosidase in the Apo and GM3 Ganglioside-bound Forms.
J.Biol.Chem., 282, 2007
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2OSW
 | | Endo-glycoceramidase II from Rhodococcus sp. | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoglycoceramidase II, SODIUM ION | | Authors: | Caines, M.E.C, Strynadka, N.C.J. | | Deposit date: | 2007-02-06 | | Release date: | 2007-02-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and Mechanistic Analyses of endo-Glycoceramidase II, a Membrane-associated Family 5 Glycosidase in the Apo and GM3 Ganglioside-bound Forms.
J.Biol.Chem., 282, 2007
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2OBL
 | | Structural and biochemical analysis of a prototypical ATPase from the type III secretion system of pathogenic bacteria | | Descriptor: | ACETATE ION, CALCIUM ION, EscN, ... | | Authors: | Zarivach, R, Vuckovic, M, Deng, W, Finlay, B.B, Strynadka, N.C.J. | | Deposit date: | 2006-12-19 | | Release date: | 2007-01-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural analysis of a prototypical ATPase from the type III secretion system.
Nat.Struct.Mol.Biol., 14, 2007
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2OBM
 | | Structural and biochemical analysis of a prototypical ATPase from the type III secretion system of pathogenic bacteria | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, EscN | | Authors: | Zarivach, R, Vuckovic, M, Deng, W, Finlay, B.B, Strynadka, N.C.J. | | Deposit date: | 2006-12-19 | | Release date: | 2007-01-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural analysis of a prototypical ATPase from the type III secretion system.
Nat.Struct.Mol.Biol., 14, 2007
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2QF5
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2OLV
 | | Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex | | Descriptor: | MOENOMYCIN, Penicillin-binding protein 2 | | Authors: | Lovering, A.L, De Castro, L, Lim, D, Strynadka, N.C.J. | | Deposit date: | 2007-01-19 | | Release date: | 2007-03-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis.
Science, 315, 2007
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2OYL
 | | Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like imidazole complex | | Descriptor: | (5R,6R,7R,8S)-7,8-dihydroxy-5-(hydroxymethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-6-yl beta-D-glucopyranoside, Endoglycoceramidase II, GLYCEROL, ... | | Authors: | Caines, M.E.C, Strynadka, N.C.J. | | Deposit date: | 2007-02-22 | | Release date: | 2007-03-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.
Angew.Chem.Int.Ed.Engl., 46, 2007
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2QF4
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1EYR
 | | Structure of a sialic acid activating synthetase, CMP acylneuraminate synthetase in the presence and absence of CDP | | Descriptor: | CMP-N-ACETYLNEURAMINIC ACID SYNTHETASE, CYTIDINE-5'-DIPHOSPHATE | | Authors: | Mosimann, S.C, Gilbert, M, Dombrowski, D, Wakarchuk, W, Strynadka, N.C. | | Deposit date: | 2000-05-08 | | Release date: | 2001-02-14 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of a sialic acid-activating synthetase, CMP-acylneuraminate synthetase in the presence and absence of CDP.
J.Biol.Chem., 276, 2001
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1B12
 | | CRYSTAL STRUCTURE OF TYPE 1 SIGNAL PEPTIDASE FROM ESCHERICHIA COLI IN COMPLEX WITH A BETA-LACTAM INHIBITOR | | Descriptor: | PHOSPHATE ION, SIGNAL PEPTIDASE I, prop-2-en-1-yl (2S)-2-[(2S,3R)-3-(acetyloxy)-1-oxobutan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylate | | Authors: | Paetzel, M, Dalbey, R, Strynadka, N.C.J. | | Deposit date: | 1999-11-24 | | Release date: | 1999-12-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor.
Nature, 396, 1998
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1DLI
 | | THE FIRST STRUCTURE OF UDP-GLUCOSE DEHYDROGENASE (UDPGDH) REVEALS THE CATALYTIC RESIDUES NECESSARY FOR THE TWO-FOLD OXIDATION | | Descriptor: | GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | | Authors: | Campbell, R.E, Mosimann, S.C, van de Rijn, I, Tanner, M.E, Strynadka, N.C.J. | | Deposit date: | 1999-12-09 | | Release date: | 2000-05-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | The first structure of UDP-glucose dehydrogenase reveals the catalytic residues necessary for the two-fold oxidation.
Biochemistry, 39, 2000
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1DLJ
 | | THE FIRST STRUCTURE OF UDP-GLUCOSE DEHYDROGENASE (UDPGDH) REVEALS THE CATALYTIC RESIDUES NECESSARY FOR THE TWO-FOLD OXIDATION | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... | | Authors: | Campbell, R.E, Mosimann, S.C, van de Rijn, I, Tanner, M.E, Strynadka, N.C.J. | | Deposit date: | 1999-12-09 | | Release date: | 2000-05-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The first structure of UDP-glucose dehydrogenase reveals the catalytic residues necessary for the two-fold oxidation.
Biochemistry, 39, 2000
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1ERQ
 | | X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-1-ACETAMIDO-2-(3-CARBOXY-2-HYDROXYPHENYL)ETHYL BORONIC ACID | | Descriptor: | 1(R)-1-ACETAMIDO-2-(3-CARBOXY-2-HYDROXYPHENYL)ETHYL BORONIC ACID, TEM-1 BETA-LACTAMASE | | Authors: | Ness, S, Martin, R, Kindler, A.M, Paetzel, M, Gold, M, Jones, J.B, Strynadka, N.C.J. | | Deposit date: | 2000-04-06 | | Release date: | 2000-05-10 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,).
Biochemistry, 39, 2000
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3IR6
 | | Crystal structure of NarGHI mutant NarG-H49S | | Descriptor: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, FE3-S4 CLUSTER, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Bertero, M.G, Rothery, R.A, Weiner, J.H, Strynadka, N.C.J. | | Deposit date: | 2009-08-21 | | Release date: | 2010-01-05 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Protein crystallography reveals a role for the FS0 cluster of Escherichia coli nitrate reductase A (NarGHI) in enzyme maturation.
J.Biol.Chem., 285, 2010
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1EZI
 | | Structure of a sialic acid activating synthetase, CMP acylneuraminate synthetase in the presence and absence of CDP | | Descriptor: | CMP-N-ACETYLNEURAMINIC ACID SYNTHETASE | | Authors: | Mosimann, S.C, Gilbert, M, Dombrowski, D, Wakarchuk, W, Strynadka, N.C. | | Deposit date: | 2000-05-11 | | Release date: | 2001-02-14 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of a sialic acid-activating synthetase, CMP-acylneuraminate synthetase in the presence and absence of CDP.
J.Biol.Chem., 276, 2001
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3IR5
 | | Crystal structure of NarGHI mutant NarG-H49C | | Descriptor: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, FE3-S4 CLUSTER, IRON/SULFUR CLUSTER, ... | | Authors: | Bertero, M.G, Rothery, R.A, Weiner, J.H, Strynadka, N.C.J. | | Deposit date: | 2009-08-21 | | Release date: | 2010-01-05 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Protein crystallography reveals a role for the FS0 cluster of Escherichia coli nitrate reductase A (NarGHI) in enzyme maturation.
J.Biol.Chem., 285, 2010
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