2OYM

Endo-glycoceramidase II from Rhodococcus sp.: five-membered iminocyclitol complex

Summary for 2OYM

• Entry DOI: 10.2210/pdb2oym/pdb
• Descriptor: Endoglycoceramidase II, SODIUM ION, N-{[(2R,3R,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PYRROLIDIN-2-YL]METHYL}-4-(DIMETHYLAMINO)BENZAMIDE, ... (4 entities in total)
• Functional Keywords: (alpha/beta)8 (tim) barrel, hydrolase
• Biological source: Rhodococcus sp.
• Total number of polymer chains: 2
• Total formula weight: 104909.77

Authors

Caines, M.E.C.,Strynadka, N.C.J. (deposition date: 2007-02-22, release date: 2007-03-06, Last modification date: 2023-08-30)

• Primary citation: Caines, M.E.,Hancock, S.M.,Tarling, C.A.,Wrodnigg, T.M.,Stick, R.V.,Stutz, A.E.,Vasella, A.,Withers, S.G.,Strynadka, N.C.; The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.; Angew.Chem.Int.Ed.Engl., 46:4474-4476, 2007; PubMed: 17487923; DOI: 10.1002/anie.200700268

Experimental method

X-RAY DIFFRACTION (1.86 Å)