2OYL

Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like imidazole complex

Summary for 2OYL

• Entry DOI: 10.2210/pdb2oyl/pdb
• Descriptor: Endoglycoceramidase II, SODIUM ION, (5R,6R,7R,8S)-7,8-dihydroxy-5-(hydroxymethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-6-yl beta-D-glucopyranoside, ... (5 entities in total)
• Functional Keywords: (alpha/beta)8 (tim) barrel, hydrolase
• Biological source: Rhodococcus sp.
• Total number of polymer chains: 2
• Total formula weight: 105245.88

Authors

Caines, M.E.C.,Strynadka, N.C.J. (deposition date: 2007-02-22, release date: 2007-03-06, Last modification date: 2023-08-30)

• Primary citation: Caines, M.E.,Hancock, S.M.,Tarling, C.A.,Wrodnigg, T.M.,Stick, R.V.,Stutz, A.E.,Vasella, A.,Withers, S.G.,Strynadka, N.C.; The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.; Angew.Chem.Int.Ed.Engl., 46:4474-4476, 2007; PubMed: 17487923; DOI: 10.1002/anie.200700268

Experimental method

X-RAY DIFFRACTION (1.8 Å)