7WBM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wbm by Molmil](/molmil-images/mine/7wbm) | Crystal structure of Legionella pneumophila effector protein Lpg0081 | Descriptor: | Lpg0081, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | Authors: | Lee, J, Kim, H, Oh, B.H. | Deposit date: | 2021-12-17 | Release date: | 2022-06-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7UYG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uyg by Molmil](/molmil-images/mine/7uyg) | |
7UYH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uyh by Molmil](/molmil-images/mine/7uyh) | |
5X1V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x1v by Molmil](/molmil-images/mine/5x1v) | PKM2 in complex with compound 2 | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 4-[2,3-bis(chloranyl)phenyl]carbonyl-1-methyl-pyrrole-2-carboxamide, Pyruvate kinase PKM | Authors: | Matsui, Y, Hanzawa, H. | Deposit date: | 2017-01-27 | Release date: | 2017-05-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator Bioorg. Med. Chem., 25, 2017
|
|
5X1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x1w by Molmil](/molmil-images/mine/5x1w) | PKM2 in complex with compound 5 | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 4-[2,3-bis(chloranyl)phenyl]carbonyl-N-[2-[[4-[2,3-bis(chloranyl)phenyl]carbonyl-1-methyl-pyrrol-2-yl]carbonylamino]ethyl]-1-methyl-pyrrole-2-carboxamide, Pyruvate kinase PKM | Authors: | Matsui, Y, Hanzawa, H. | Deposit date: | 2017-01-27 | Release date: | 2017-05-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator Bioorg. Med. Chem., 25, 2017
|
|
2RLT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rlt by Molmil](/molmil-images/mine/2rlt) | phosphorylated CPI-17 (22-120) | Descriptor: | Protein phosphatase 1 regulatory subunit 14A | Authors: | Eto, M. | Deposit date: | 2007-08-11 | Release date: | 2008-07-15 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor. Structure, 15, 2007
|
|
2ZZU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zzu by Molmil](/molmil-images/mine/2zzu) | Human Factor VIIA-Tissue Factor Complexed with ethylsulfonamide-D-5-(3-carboxybenzyloxy)-Trp-Gln-p-aminobenzamidine | Descriptor: | 3-[[3-[(2R)-3-[[(2S)-5-amino-1-[(4-carbamimidoylphenyl)methylamino]-1,5-dioxo-pentan-2-yl]amino]-2-(ethylsulfonylamino)-3-oxo-propyl]-1H-indol-5-yl]oxymethyl]benzoic acid, CALCIUM ION, Factor VII heavy chain, ... | Authors: | Kadono, S, Sakamoto, A, Kikuchi, Y, Oh-Eda, M, Yabuta, N, Koga, T, Hattori, K, Shiraishi, T, Haramura, M, Sato, H, Ohta, M, Kozono, T. | Deposit date: | 2009-02-25 | Release date: | 2009-03-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Design and synthesis of peptidomimetic factor VIIa inhibitors Chem.Pharm.Bull., 58, 2010
|
|
3A71
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a71 by Molmil](/molmil-images/mine/3a71) | |
3A72
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a72 by Molmil](/molmil-images/mine/3a72) | |
3P1Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3p1z by Molmil](/molmil-images/mine/3p1z) | Crystal structure of the Aperopyrum pernix RNA splicing endonuclease | Descriptor: | Putative uncharacterized protein, tRNA-splicing endonuclease | Authors: | Hirata, A. | Deposit date: | 2010-10-01 | Release date: | 2011-08-10 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop Nucleic Acids Res., 39, 2011
|
|
8H4V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h4v by Molmil](/molmil-images/mine/8h4v) | Mincle CRD complex with PGL trisaccharide | Descriptor: | (2~{R},3~{R},4~{S},5~{S},6~{R})-6-(methoxymethyl)oxane-2,3,4,5-tetrol-(1-4)-6-deoxy-2,3-di-O-methyl-alpha-L-mannopyranose-(1-2)-3-O-methyl-alpha-L-rhamnopyranose, C-type lectin domain family 4 member E, CALCIUM ION | Authors: | Ishizuka, S, Nagae, M, Yamasaki, S. | Deposit date: | 2022-10-11 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand. Acs Cent.Sci., 9, 2023
|
|
8HB5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hb5 by Molmil](/molmil-images/mine/8hb5) | Crystal structure of Mincle in complex with HD-275 | Descriptor: | (2~{R},3~{R},4~{S},5~{S},6~{R})-6-(methoxymethyl)oxane-2,3,4,5-tetrol, C-type lectin domain family 4 member E, CALCIUM ION | Authors: | Ishizuka, S, Nagae, M, Yamasaki, S. | Deposit date: | 2022-10-27 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand. Acs Cent.Sci., 9, 2023
|
|
1MG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mg8 by Molmil](/molmil-images/mine/1mg8) | NMR structure of ubiquitin-like domain in murine Parkin | Descriptor: | Parkin | Authors: | Tashiro, M, Okubo, S, Shimotakahara, S, Hatanaka, H, Yasuda, H, Kainosho, M, Yokoyama, S, Shindo, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-08-15 | Release date: | 2003-04-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR structure of ubiquitin-like domain in PARKIN: Gene product of familial Parkinson's disease. J.Biomol.NMR, 25, 2003
|
|
2BJ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bj8 by Molmil](/molmil-images/mine/2bj8) | |
2BJ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bj9 by Molmil](/molmil-images/mine/2bj9) | NIKR with bound NICKEL and phosphate | Descriptor: | NICKEL (II) ION, NICKEL RESPONSIVE REGULATOR, PHOSPHATE ION, ... | Authors: | Tahirov, T.H, Chivers, P.T. | Deposit date: | 2005-01-31 | Release date: | 2005-04-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition J.Mol.Biol., 348, 2005
|
|
2BJ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bj7 by Molmil](/molmil-images/mine/2bj7) | |
2BJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bj3 by Molmil](/molmil-images/mine/2bj3) | NIKR-apo | Descriptor: | CHLORIDE ION, MAGNESIUM ION, NICKEL RESPONSIVE REGULATOR | Authors: | Tahirov, T.H. | Deposit date: | 2005-01-28 | Release date: | 2005-04-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition J.Mol.Biol., 348, 2005
|
|
2BJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bj1 by Molmil](/molmil-images/mine/2bj1) | NIKR IN OPEN CONFORMATION AND NICKEL BOUND TO HIGH-AFFINITY SITES | Descriptor: | CHLORIDE ION, NICKEL (II) ION, NICKEL RESPONSIVE REGULATOR | Authors: | Tahirov, T.H. | Deposit date: | 2005-01-27 | Release date: | 2005-04-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition J.Mol.Biol., 348, 2005
|
|