1WKH
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![BU of 1wkh by Molmil](/molmil-images/mine/1wkh) | Acetylornithine aminotransferase from thermus thermophilus HB8 | Descriptor: | 4-[(1,3-DICARBOXY-PROPYLAMINO)-METHYL]-3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDINIUM, Acetylornithine/acetyl-lysine aminotransferase | Authors: | Matsumura, M, Goto, M, Omi, R, Miyahara, I, Hirotsu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-31 | Release date: | 2005-09-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Acetylornithine aminotransferase from thermus thermophilus HB8 To be Published
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1WKG
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![BU of 1wkg by Molmil](/molmil-images/mine/1wkg) | Acetylornithine aminotransferase from thermus thermophilus HB8 | Descriptor: | Acetylornithine/acetyl-lysine aminotransferase, N~2~-ACETYL-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-ORNITHINE | Authors: | Matsumura, M, Goto, M, Omi, R, Miyahara, I, Hirotsu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-31 | Release date: | 2005-09-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Acetylornithine aminotransferase from thermus thermophilus HB8 To be Published
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6IUE
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![BU of 6iue by Molmil](/molmil-images/mine/6iue) | DNA helical wire containing Hg(II) | Descriptor: | DNA (5'-D(*TP*TP*TP*GP*C)-3'), MERCURY (II) ION | Authors: | Ono, A, Kanazawa, H, Ito, H, Goto, M, Nakamura, K, Saneyoshi, H, Kondo, J. | Deposit date: | 2018-11-28 | Release date: | 2019-10-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | A Novel DNA Helical Wire Containing HgII-Mediated T:T and T:G Pairs. Angew.Chem.Int.Ed.Engl., 58, 2019
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1IQ0
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![BU of 1iq0 by Molmil](/molmil-images/mine/1iq0) | THERMUS THERMOPHILUS ARGINYL-TRNA SYNTHETASE | Descriptor: | ARGINYL-TRNA SYNTHETASE | Authors: | Shimada, A, Nureki, O, Goto, M, Takahashi, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-05-24 | Release date: | 2001-11-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and mutational studies of the recognition of the arginine tRNA-specific major identity element, A20, by arginyl-tRNA synthetase. Proc.Natl.Acad.Sci.USA, 98, 2001
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5YBW
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![BU of 5ybw by Molmil](/molmil-images/mine/5ybw) | Crystal structure of pyridoxal 5'-phosphate-dependent aspartate racemase | Descriptor: | Aspartate racemase | Authors: | Mizobuchi, T, Nonaka, R, Yoshimura, M, Abe, K, Takahashi, S, Kera, Y, Goto, M. | Deposit date: | 2017-09-05 | Release date: | 2017-12-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a pyridoxal 5'-phosphate-dependent aspartate racemase derived from the bivalve mollusc Scapharca broughtonii Acta Crystallogr F Struct Biol Commun, 73, 2017
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1WUP
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![BU of 1wup by Molmil](/molmil-images/mine/1wup) | Crystal structure of metallo-beta-lactamase IMP-1 mutant (D81E) | Descriptor: | ACETIC ACID, Beta-lactamase IMP-1, ZINC ION | Authors: | Yamaguchi, Y, Yamagata, Y, Goto, M. | Deposit date: | 2004-12-08 | Release date: | 2005-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography. J.Biol.Chem., 280, 2005
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1WUO
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![BU of 1wuo by Molmil](/molmil-images/mine/1wuo) | Crystal structure of metallo-beta-lactamase IMP-1 mutant (D81A) | Descriptor: | ACETIC ACID, Beta-lactamase IMP-1, ZINC ION | Authors: | Yamaguchi, Y, Yamagata, Y, Goto, M. | Deposit date: | 2004-12-08 | Release date: | 2005-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography. J.Biol.Chem., 280, 2005
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1VGN
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![BU of 1vgn by Molmil](/molmil-images/mine/1vgn) | Structure-based design of the irreversible inhibitors to metallo--lactamase (IMP-1) | Descriptor: | 3-OXO-3-[(3-OXOPROPYL)SULFANYL]PROPANE-1-THIOLATE, ACETIC ACID, Beta-lactamase IMP-1, ... | Authors: | Kurosaki, H, Yamaguchi, Y, Higashi, T, Soga, K, Matsueda, S, Misumi, S, Yamagata, Y, Arakawa, Y, Goto, M. | Deposit date: | 2004-04-27 | Release date: | 2005-06-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Irreversible Inhibition of Metallo-beta-lactamase (IMP-1) by 3-(3-Mercaptopropionylsulfanyl)propionic Acid Pentafluorophenyl Ester Angew.Chem.Int.Ed.Engl., 44, 2005
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7Y4K
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![BU of 7y4k by Molmil](/molmil-images/mine/7y4k) | Crystal structure of Ricin A chain bound with N2-(2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)glycyl-L-phenylalanyl-N6-((benzyloxy)carbonyl)-L-ornitine | Descriptor: | (2S)-2-[[(2S)-2-[2-[(2-azanyl-4-oxidanylidene-3H-pteridin-7-yl)carbonylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-5-(phenylmethoxycarbonylamino)pentanoic acid, Ricin A chain, SULFATE ION | Authors: | Katakura, S, Goto, M, Ohba, T, Kawata, R, Nagatsu, K, Higashi, S, Matsumoto, K, Kurisu, K, Ohtsuka, K, Saito, R. | Deposit date: | 2022-06-15 | Release date: | 2022-11-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain. Plos One, 17, 2022
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7Y4M
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![BU of 7y4m by Molmil](/molmil-images/mine/7y4m) | Crystal structure of Ricin A chain bound with N2-(2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)glycyl-L-phenylalanyl-N6-((benzyloxy)carbonyl)-L-lysine | Descriptor: | (2S)-2-[[(2S)-2-[2-[(2-azanyl-4-oxidanylidene-3H-pteridin-7-yl)carbonylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-6-(phenylmethoxycarbonylamino)hexanoic acid, Ricin A chain, SULFATE ION | Authors: | Katakura, S, Goto, M, Ohba, T, Kawata, R, Nagatsu, K, Higashi, S, Matsumoto, K, Kurisu, K, Ohtsuka, K, Saito, R. | Deposit date: | 2022-06-15 | Release date: | 2022-11-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain. Plos One, 17, 2022
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2DOU
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![BU of 2dou by Molmil](/molmil-images/mine/2dou) | probable N-succinyldiaminopimelate aminotransferase (TTHA0342) from Thermus thermophilus HB8 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, probable N-succinyldiaminopimelate aminotransferase | Authors: | Omi, R, Goto, M, Miyahara, I, Hirotsu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-05-03 | Release date: | 2006-11-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | probable N-succinyldiaminopimelate aminotransferase (TTHA0342) from Thermus thermophilus HB8 To be published
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2DQ4
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![BU of 2dq4 by Molmil](/molmil-images/mine/2dq4) | Crystal structure of threonine 3-dehydrogenase | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, L-threonine 3-dehydrogenase, ZINC ION | Authors: | Omi, R, Yao, T, Goto, M, Miyahara, I, Hirotsu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-05-19 | Release date: | 2007-06-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of threonine 3-dehydrogenase To be Published
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2EJV
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![BU of 2ejv by Molmil](/molmil-images/mine/2ejv) | Crystal structure of threonine 3-dehydrogenase complexed with NAD+ | Descriptor: | L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | Authors: | Omi, R, Yao, T, Goto, M, Miyahara, I, Hirotsu, K. | Deposit date: | 2007-03-20 | Release date: | 2008-03-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structure of threonine 3-dehydrogenase To be Published
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2EJW
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![BU of 2ejw by Molmil](/molmil-images/mine/2ejw) | Homoserine Dehydrogenase from Thermus thermophilus HB8 | Descriptor: | GLYCEROL, Homoserine dehydrogenase, MAGNESIUM ION, ... | Authors: | Omi, R, Goto, M, Miyahara, I, Hirotsu, K. | Deposit date: | 2007-03-21 | Release date: | 2008-02-12 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Homoserine Dehydrogenase from Thermus thermophilus HB8 To be Published
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1RKR
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![BU of 1rkr by Molmil](/molmil-images/mine/1rkr) | CRYSTAL STRUCTURE OF AZURIN-I FROM ALCALIGENES XYLOSOXIDANS NCIMB 11015 | Descriptor: | AZURIN-I, COPPER (II) ION | Authors: | Li, C, Inoue, T, Gotowda, M, Suzuki, S, Yamaguchi, K, Kataoka, K, Kai, Y. | Deposit date: | 1997-05-17 | Release date: | 1998-05-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of azurin I from the denitrifying bacterium Alcaligenes xylosoxidans NCIMB 11015 at 2.45 A resolution. Acta Crystallogr.,Sect.D, 54, 1998
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1BYO
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![BU of 1byo by Molmil](/molmil-images/mine/1byo) | WILD-TYPE PLASTOCYANIN FROM SILENE | Descriptor: | COPPER (II) ION, PROTEIN (PLASTOCYANIN) | Authors: | Sugawara, H, Inoue, T, Li, C, Gotowda, M, Hibino, T, Takabe, T, Kai, Y. | Deposit date: | 1998-10-19 | Release date: | 1999-10-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of wild-type and mutant plastocyanins from a higher plant, Silene. J.Biochem.(Tokyo), 125, 1999
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1BYP
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![BU of 1byp by Molmil](/molmil-images/mine/1byp) | E43K,D44K DOUBLE MUTANT PLASTOCYANIN FROM SILENE | Descriptor: | COPPER (II) ION, PROTEIN (PLASTOCYANIN) | Authors: | Sugawara, H, Inoue, T, Li, C, Gotowda, M, Hibino, T, Takabe, T, Kai, Y. | Deposit date: | 1998-10-19 | Release date: | 1999-10-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures of wild-type and mutant plastocyanins from a higher plant, Silene. J.Biochem.(Tokyo), 125, 1999
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1BQ5
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![BU of 1bq5 by Molmil](/molmil-images/mine/1bq5) | NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS GIFU 1051 | Descriptor: | COPPER (II) ION, NITRITE REDUCTASE | Authors: | Inoue, T, Gotowda, M, Deligeer, Suzuki, S, Kataoka, K, Yamaguchi, K, Watanabe, H, Goho, M, Yasushi, K.A.I. | Deposit date: | 1998-08-21 | Release date: | 1999-08-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Type 1 Cu structure of blue nitrite reductase from Alcaligenes xylosoxidans GIFU 1051 at 2.05 A resolution: comparison of blue and green nitrite reductases. J.Biochem.(Tokyo), 124, 1998
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1KDJ
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![BU of 1kdj by Molmil](/molmil-images/mine/1kdj) | OXIDIZED FORM OF PLASTOCYANIN FROM DRYOPTERIS CRASSIRHIZOMA | Descriptor: | COPPER (II) ION, PLASTOCYANIN | Authors: | Inoue, T, Gotowda, M, Hamada, K, Kohzuma, T, Yoshizaki, F, Sugimura, Y, Kai, Y. | Deposit date: | 1998-05-08 | Release date: | 1999-05-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structure and unusual pH dependence of plastocyanin from the fern Dryopteris crassirhizoma. The protonation of an active site histidine is hindered by pi-pi interactions. J.Biol.Chem., 274, 1999
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1KDI
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![BU of 1kdi by Molmil](/molmil-images/mine/1kdi) | REDUCED FORM OF PLASTOCYANIN FROM DRYOPTERIS CRASSIRHIZOMA | Descriptor: | COPPER (II) ION, PLASTOCYANIN | Authors: | Inoue, T, Gotowda, M, Hamada, K, Kohzuma, T, Yoshizaki, F, Sugimura, Y, Kai, Y. | Deposit date: | 1998-05-08 | Release date: | 1999-05-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure and unusual pH dependence of plastocyanin from the fern Dryopteris crassirhizoma. The protonation of an active site histidine is hindered by pi-pi interactions. J.Biol.Chem., 274, 1999
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1VC3
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5WJJ
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![BU of 5wjj by Molmil](/molmil-images/mine/5wjj) | Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors | Descriptor: | Mitogen-activated protein kinase 14, N-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide | Authors: | Snell, G.P, Okada, K, Bragstad, K, Sang, B.-C. | Deposit date: | 2017-07-23 | Release date: | 2018-01-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors. Bioorg. Med. Chem., 26, 2018
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6AHS
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![BU of 6ahs by Molmil](/molmil-images/mine/6ahs) | Mouse Kallikrein 7 in complex with imidazolinylindole derivative | Descriptor: | 1-[(2-chlorophenyl)sulfonyl]-5-methyl-3-[(4R)-2-methyl-4,5-dihydro-1H-imidazol-4-yl]-1H-indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | Authors: | Sugawara, H. | Deposit date: | 2018-08-20 | Release date: | 2019-01-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors. Bioorg. Med. Chem. Lett., 29, 2019
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8GZC
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![BU of 8gzc by Molmil](/molmil-images/mine/8gzc) | Crystal structure of EP300 HAT domain in complex with compound 10 | Descriptor: | (2~{R},4~{R})-4-fluoranyl-1-[1-(4-methoxyphenyl)cyclohexyl]carbonyl-~{N}-(1~{H}-pyrazolo[4,3-b]pyridin-5-yl)pyrrolidine-2-carboxamide, Histone acetyltransferase p300, ZINC ION | Authors: | Takahashi, M, Hanzawa, H. | Deposit date: | 2022-09-26 | Release date: | 2023-01-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor. J.Med.Chem., 66, 2023
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8H4V
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![BU of 8h4v by Molmil](/molmil-images/mine/8h4v) | Mincle CRD complex with PGL trisaccharide | Descriptor: | (2~{R},3~{R},4~{S},5~{S},6~{R})-6-(methoxymethyl)oxane-2,3,4,5-tetrol-(1-4)-6-deoxy-2,3-di-O-methyl-alpha-L-mannopyranose-(1-2)-3-O-methyl-alpha-L-rhamnopyranose, C-type lectin domain family 4 member E, CALCIUM ION | Authors: | Ishizuka, S, Nagae, M, Yamasaki, S. | Deposit date: | 2022-10-11 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand. Acs Cent.Sci., 9, 2023
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