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3MRC
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BU of 3mrc by Molmil
Crystal Structure of MHC class I HLA-A2 molecule complexed with HCMV pp65-495-503 nonapeptide V6C variant
Descriptor: 9-meric peptide from Tegument protein pp65, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Reiser, J.-B, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D.
Deposit date:2010-04-29
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans.
J.Immunol., 193, 2014
1MW4
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BU of 1mw4 by Molmil
Solution structure of the human Grb7-SH2 domain in complex with a 10 amino acid peptide pY1139
Descriptor: Growth factor receptor-bound protein 7, Receptor protein-tyrosine kinase erbB-2
Authors:Ivancic, M, Lyons, B.A.
Deposit date:2002-09-27
Release date:2003-09-09
Last modified:2012-05-02
Method:SOLUTION NMR
Cite:Solution structure of the human Grb7-SH2 domain/erbB2 peptide complex and structural basis for Grb7 binding to ErbB2
J.BIOMOL.NMR, 27, 2003
3M5Q
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BU of 3m5q by Molmil
0.93 A Structure of Manganese-Bound Manganese Peroxidase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Sundaramoorthy, M, Gold, M.H, Poulos, T.L.
Deposit date:2010-03-12
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:Ultrahigh (0.93A) resolution structure of manganese peroxidase from Phanerochaete chrysosporium: implications for the catalytic mechanism.
J.Inorg.Biochem., 104, 2010
3MKM
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BU of 3mkm by Molmil
Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)
Descriptor: CALCIUM ION, Putative uncharacterized protein YeiK
Authors:Garau, G, Fornili, A, Giabbai, B, Degano, M.
Deposit date:2010-04-15
Release date:2010-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Energy Landscapes Associated with Macromolecular Conformational Changes from Endpoint Structures
J.Am.Chem.Soc., 132, 2010
7SGS
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BU of 7sgs by Molmil
Cryo-EM structure of full-length MAP7 bound to the microtubule
Descriptor: Ensconsin, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Ferro, L.S, Fang, Q, Eshun-Wilson, L, Fernandes, J, Jack, A, Farrell, D.P, Golcuk, M, Huijben, T, Costa, K, Gur, M, DiMaio, F, Nogales, E, Yildiz, A.
Deposit date:2021-10-07
Release date:2022-05-18
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein MAP7.
Science, 375, 2022
3MSL
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BU of 3msl by Molmil
Fragment Based Discovery and Optimisation of BACE-1 Inhibitors
Descriptor: (3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(cyclohexylmethyl)pentanamide, Beta-secretase 1, IODIDE ION
Authors:Smith, M, Madden, J, Barker, J.
Deposit date:2010-04-29
Release date:2010-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Fragment-based discovery and optimization of BACE1 inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
7RUQ
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BU of 7ruq by Molmil
Structure of the human GIGYF1-TNRC6C complex
Descriptor: GRB10-interacting GYF protein 1, Trinucleotide repeat-containing gene 6C protein
Authors:Sobti, M, Mead, B.J, Igreja, C, Stewart, A.G, Christie, M.
Deposit date:2021-08-18
Release date:2022-08-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Molecular basis for GIGYF-TNRC6 complex assembly.
Rna, 29, 2023
3MML
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BU of 3mml by Molmil
Allophanate Hydrolase Complex from Mycobacterium smegmatis, Msmeg0435-Msmeg0436
Descriptor: Allophanate hydrolase subunit 1, Allophanate hydrolase subunit 2, CHLORIDE ION
Authors:Kaufmann, M, Chernishof, I, Shin, A, Germano, D, Sawaya, M.R, Waldo, G.S, Arbing, M.A, Perry, J, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-04-20
Release date:2010-04-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Allphanate Hydrolase Complex from M. smegmatis, Msmeg0435-Msmeg0436
To be Published
7RUP
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BU of 7rup by Molmil
Structure of the human GIGYF2-TNRC6A complex
Descriptor: GRB10-interacting GYF protein 2, SULFATE ION, Trinucleotide repeat-containing gene 6A protein
Authors:Sobti, M, Mead, B.J, Igreja, C, Stewart, A.G, Christie, M.
Deposit date:2021-08-18
Release date:2022-08-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Molecular basis for GIGYF-TNRC6 complex assembly.
Rna, 29, 2023
3MRE
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BU of 3mre by Molmil
Crystal Structure of MHC class I HLA-A2 molecule complexed with EBV bmlf1-280-288 nonapeptide
Descriptor: 9-meric peptide from mRNA export factor EB2, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D.
Deposit date:2010-04-29
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans.
J.Immunol., 193, 2014
4UXD
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BU of 4uxd by Molmil
2-keto 3-deoxygluconate aldolase from Picrophilus torridus
Descriptor: 1,2-ETHANEDIOL, 2-DEHYDRO-3-DEOXY-D-GLUCONATE/2-DEHYDRO-3-DEOXY-PHOSPHOGLUCONATE ALDOLASE, DI(HYDROXYETHYL)ETHER, ...
Authors:Priftis, A, Zaitsev, V, Reher, M, Johnsen, U, Danson, M.J, Taylor, G.L, Schoenheit, P, Crennell, S.J.
Deposit date:2014-08-22
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases: The Structures of Picrophilus torridus 2-Keto-3-deoxygluconate Aldolase and Sulfolobus solfataricus 2-Keto-3-deoxy-6-phosphogluconate Aldolase in Complex with 2-Keto-3-deoxy-6-phosphogluconate.
Biochemistry, 57, 2018
6LNG
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BU of 6lng by Molmil
Rapid crystallization of streptavidin using charged peptides
Descriptor: GLYCEROL, Streptavidin
Authors:Minamihata, K, Tsukamoto, K, Adachi, M, Shimizu, R, Mishina, M, Kuroki, R, Nagamune, T.
Deposit date:2019-12-30
Release date:2020-03-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8000015 Å)
Cite:Genetically fused charged peptides induce rapid crystallization of proteins.
Chem.Commun.(Camb.), 56, 2020
6LP1
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BU of 6lp1 by Molmil
Crystal structure of acetate:succinate CoA transferase (ASCT) from Trypanosoma brucei.
Descriptor: CALCIUM ION, GLYCEROL, Succinyl-CoA:3-ketoacid-coenzyme A transferase
Authors:Mochizuki, K, Inaoka, D.K, Shiba, T, Fukuda, K, Kurasawa, H, Mazet, M, Millerioux, Y, Bringaud, F, Boshart, M, Balogun, E.O, Harada, S, Hirayama, K, Kita, K.
Deposit date:2020-01-08
Release date:2020-10-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei.
Biochim Biophys Acta Bioenerg, 1861, 2020
4ZI2
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BU of 4zi2 by Molmil
BART-like domain of BARTL1/CCDC104 in complex with Arl3FL bound to GppNHp in P21 21 21
Descriptor: ADP-ribosylation factor-like protein 3, Cilia- and flagella-associated protein 36, MAGNESIUM ION, ...
Authors:Lokaj, M, Koerner, C, Koesling, S, Wittinghofer, A.
Deposit date:2015-04-27
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.
Structure, 23, 2015
1E8L
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BU of 1e8l by Molmil
NMR solution structure of hen lysozyme
Descriptor: LYSOZYME
Authors:Schwalbe, H, Grimshaw, S.B, Spencer, A, Buck, M, Boyd, J, Dobson, C.M, Redfield, C, Smith, L.J.
Deposit date:2000-09-27
Release date:2000-10-09
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:A refined solution structure of hen lysozyme determined using residual dipolar coupling data.
Protein Sci., 10, 2001
1EKG
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BU of 1ekg by Molmil
MATURE HUMAN FRATAXIN
Descriptor: FRATAXIN
Authors:Dhe-Paganon, S, Shigeta, R, Chi, Y.I, Ristow, M, Shoelson, S.E.
Deposit date:2000-03-08
Release date:2000-11-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human frataxin.
J.Biol.Chem., 275, 2000
4PH8
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BU of 4ph8 by Molmil
Crystal structure of AggA, the major subunit of aggregative adherence fimbriae type I (AAF/I) from the Escherichia coli O4H104
Descriptor: Aggregative adherence fimbrial subunit AggA, GLYCEROL
Authors:Pakharukova, N.A, Tuitilla, M, Zavialov, A.V.
Deposit date:2014-05-05
Release date:2014-10-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli.
Plos Pathog., 10, 2014
1EKP
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BU of 1ekp by Molmil
CRYSTAL STRUCTURE OF HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL) COMPLEXED WITH PYRIDOXAL-5'-PHOSPHATE AT 2.5 ANGSTROMS (MONOCLINIC FORM).
Descriptor: BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL), PYRIDOXAL-5'-PHOSPHATE
Authors:Yennawar, N.H, Dunbar, J.H, Conway, M, Hutson, S.M, Farber, G.K.
Deposit date:2000-03-09
Release date:2001-03-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of human mitochondrial branched-chain aminotransferase.
Acta Crystallogr.,Sect.D, 57, 2001
5HKH
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BU of 5hkh by Molmil
Crystal structure of Ufm1 in complex with UBA5
Descriptor: ASP-ASN-GLU-TRP-GLY-ILE-GLU-LEU-VAL, Ubiquitin-fold modifier 1
Authors:Huber, J, Doetsch, V, Rogov, V.V, Akutsu, M.
Deposit date:2016-01-14
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation.
J.Biol.Chem., 291, 2016
1EH1
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BU of 1eh1 by Molmil
RIBOSOME RECYCLING FACTOR FROM THERMUS THERMOPHILUS
Descriptor: RIBOSOME RECYCLING FACTOR
Authors:Toyoda, T, Tin, O.F, Ito, K, Fujiwara, T, Kumasaka, T, Yamamoto, M, Garber, M.B, Nakamura, Y.
Deposit date:2000-02-18
Release date:2000-11-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure combined with genetic analysis of the Thermus thermophilus ribosome recycling factor shows that a flexible hinge may act as a functional switch.
RNA, 6, 2000
3VGD
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BU of 3vgd by Molmil
Ctystal structure of glycosyltrehalose trehalohydrolase (D252E)
Descriptor: CITRATE ANION, GLYCEROL, Malto-oligosyltrehalose trehalohydrolase
Authors:Okazaki, N, Tamada, T, Feese, M.D, Kato, M, Miura, Y, Komeda, T, Kobayashi, K, Kondo, K, Kuroki, R.
Deposit date:2011-08-09
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Substrate recognition mechanism of a glycosyltrehalose trehalohydrolase from Sulfolobus solfataricus KM1.
Protein Sci., 21, 2012
1EKV
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BU of 1ekv by Molmil
HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL): THREE DIMENSIONAL STRUCTURE OF ENZYME INACTIVATED BY TRIS BOUND TO THE PYRIDOXAL-5'-PHOSPHATE ON ONE END AND ACTIVE SITE LYS202 NZ ON THE OTHER.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL), PYRIDOXAL-5'-PHOSPHATE
Authors:Yennawar, N.H, Dunbar, J.H, Conway, M, Hutson, S.M, Farber, G.K.
Deposit date:2000-03-09
Release date:2001-03-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The structure of human mitochondrial branched-chain aminotransferase.
Acta Crystallogr.,Sect.D, 57, 2001
1ELN
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BU of 1eln by Molmil
SOLUTION STRUCTURE OF A MODIFIED HUMAN TELOMERE FRAGMENT (STRUCTURE "S")
Descriptor: 5'-D(*CP*CP*CP*TP*AP*AP*(5CM)P*CP*CP*TP*AP*AP*CP*CP*CP*UP*AP*AP*CP*CP*CP*T)-3'
Authors:Phan, A.T, Gueron, M, Leroy, J.-L.
Deposit date:2000-03-14
Release date:2000-03-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure and internal motions of a fragment of the cytidine-rich strand of the human telomere.
J.Mol.Biol., 299, 2000
3VRT
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BU of 3vrt by Molmil
VDR ligand binding domain in complex with 2-Mehylidene-19,25,26,27-tetranor-1alpha,24-dihydroxyvitaminD3
Descriptor: (1R,3R,7E,17beta)-17-[(2R)-5-hydroxypentan-2-yl]-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, 13-meric peptide from Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor
Authors:Nakabayashi, M, Yoshimoto, N, Inaba, Y, Itoh, T, Ito, N, Yamamoto, K.
Deposit date:2012-04-14
Release date:2012-05-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Butyl pocket formation in the vitamin d receptor strongly affects the agonistic or antagonistic behavior of ligands
J.Med.Chem., 55, 2012
2GG2
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BU of 2gg2 by Molmil
Novel bacterial methionine aminopeptidase inhibitors
Descriptor: 5-IMINO-4-(3-TRIFLUOROMETHYL-PHENYLAZO)-5H-PYRAZOL-3-YLAMINE, COBALT (II) ION, Methionine aminopeptidase, ...
Authors:Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
Deposit date:2006-03-23
Release date:2006-06-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1 Å)
Cite:Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007

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