1PKX
| Crystal Structure of human ATIC in complex with XMP | Descriptor: | Bifunctional purine biosynthesis protein PURH, POTASSIUM ION, XANTHOSINE-5'-MONOPHOSPHATE | Authors: | Wolan, D.W, Cheong, C.G, Greasley, S.E, Wilson, I.A. | Deposit date: | 2003-06-06 | Release date: | 2004-02-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Insights into the Human and Avian IMP Cyclohydrolase Mechanism via Crystal Structures with the Bound XMP Inhibitor. Biochemistry, 43, 2004
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1SQ2
| Crystal Structure Analysis of the Nurse Shark New Antigen Receptor (NAR) Variable Domain in Complex With Lysozyme | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | Authors: | Stanfield, R.L, Dooley, H, Flajnik, M.F, Wilson, I.A. | Deposit date: | 2004-03-17 | Release date: | 2004-08-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of a shark single-domain antibody V region in complex with lysozyme. Science, 305, 2004
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1T4K
| Crystal Structure of Unliganded Aldolase Antibody 93F3 Fab | Descriptor: | IMMUNOGLOBULIN IGG1, HEAVY CHAIN, KAPPA LIGHT CHAIN, ... | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2004-04-29 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Origin of Enantioselectivity in Aldolase Antibodies: Crystal Structure, Site-directed Mutagenesis, and Computational Analysis J.Mol.Biol., 343, 2004
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1U9K
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1TZG
| Crystal structure of HIV-1 neutralizing human Fab 4E10 in complex with a 13-residue peptide containing the 4E10 epitope on gp41 | Descriptor: | Envelope polyprotein GP160, Fab 4E10, GLYCEROL | Authors: | Cardoso, R.M.F, Zwick, M.B, Stanfield, R.L, Kunert, R, Binley, J.M, Katinger, H, Burton, D.R, Wilson, I.A. | Deposit date: | 2004-07-09 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41 Immunity, 22, 2005
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1U7D
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5WKZ
| VH1-69 germline antibody predicted from CR6261 | Descriptor: | Immunoglobulin heavy variable 1-69D,IgG H chain, Lambda-chain (AA -20 to 215), SULFATE ION | Authors: | Lang, S, Lee, P.S. | Deposit date: | 2017-07-25 | Release date: | 2018-08-01 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Anti-idiotypic antibody K1-18 engages VH1-69 precursor and affinity-matured, anti-stem antibodies through mimicry of the HA stem To Be Published
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5XRQ
| Crystal structure of human monoclonal antibody H3v-47 | Descriptor: | Fab H3v-47 heavy chain, Fab H3v-47 light chain | Authors: | Zhang, H, Willson, I.A. | Deposit date: | 2017-06-09 | Release date: | 2018-07-25 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun, 9, 2018
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4DGU
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3B77
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2PV7
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2Q3L
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2Q86
| Structure of the mouse invariant NKT cell receptor Valpha14 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Valpha14 TCR, Vbeta8.2, ... | Authors: | Zajonc, D.M. | Deposit date: | 2007-06-08 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Valpha14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids. J.Mol.Biol., 377, 2008
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4MC7
| Crystal structure of a subtype N11 neuraminidase-like protein of A/flat-faced bat/Peru/033/2010 (H18N11) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE | Authors: | Yang, H, Carney, P.J, Chang, J.C, Guo, Z, Stevens, J. | Deposit date: | 2013-08-21 | Release date: | 2013-10-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | New world bats harbor diverse influenza a viruses. Plos Pathog., 9, 2013
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6U02
| CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab-63 Heavy Chain, Fab-63 Light Chain, ... | Authors: | Ward, A.B, Turner, H.L, Zhu, X. | Deposit date: | 2019-08-13 | Release date: | 2019-12-04 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe, 26, 2019
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6U59
| HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13B | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SOSIP.664 gp120,SOSIP.664 gp120, ... | Authors: | Yang, Y.R, Ward, A.B. | Deposit date: | 2019-08-27 | Release date: | 2020-01-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits. J.Virol., 94, 2020
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1TYP
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5HMG
| REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | Authors: | Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C. | Deposit date: | 1989-09-11 | Release date: | 1991-01-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Refinement of the influenza virus hemagglutinin by simulated annealing. J.Mol.Biol., 212, 1990
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5IHU
| Crystal structure of bovine Fab B11 | Descriptor: | bovine Fab B11 heavy chain, bovine Fab B11 light chain | Authors: | Stanfield, R, Wilson, I. | Deposit date: | 2016-02-29 | Release date: | 2016-10-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Sci Immunol, 1, 2016
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7OPB
| IL7R in complex with an antagonist | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ... | Authors: | Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N. | Deposit date: | 2021-05-31 | Release date: | 2022-05-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.144 Å) | Cite: | Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
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7B17
| SARS-CoV-spike RBD bound to two neutralising nanobodies. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama,SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama, Spike protein S1 | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2020-11-23 | Release date: | 2021-02-10 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (4.01 Å) | Cite: | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape Science, 371, 2021
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7B14
| Nanobody E bound to Spike-RBD in a localized reconstruction | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2, Spike protein S1 | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2020-11-23 | Release date: | 2021-04-28 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.79 Å) | Cite: | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape Science, 371, 2021
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7B18
| SARS-CoV-spike bound to two neutralising nanobodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 VHH E, ... | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2020-11-24 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
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5CXT
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8EH5
| Cryo-EM structure of L9 Fab in complex with rsCSP | Descriptor: | Circumsporozoite protein, L9 Heavy chain, L9 Light chain | Authors: | Martin, G.M, Ward, A.B. | Deposit date: | 2022-09-13 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9. Nat Commun, 14, 2023
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