1TZG
Crystal structure of HIV-1 neutralizing human Fab 4E10 in complex with a 13-residue peptide containing the 4E10 epitope on gp41
Summary for 1TZG
Entry DOI | 10.2210/pdb1tzg/pdb |
Descriptor | Fab 4E10, Envelope polyprotein GP160, GLYCEROL, ... (5 entities in total) |
Functional Keywords | antibody-epitope complex, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 99018.40 |
Authors | Cardoso, R.M.F.,Zwick, M.B.,Stanfield, R.L.,Kunert, R.,Binley, J.M.,Katinger, H.,Burton, D.R.,Wilson, I.A. (deposition date: 2004-07-09, release date: 2005-03-01, Last modification date: 2023-08-23) |
Primary citation | Cardoso, R.M.F.,Zwick, M.B.,Stanfield, R.L.,Kunert, R.,Binley, J.M.,Katinger, H.,Burton, D.R.,Wilson, I.A. Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41 Immunity, 22:163-173, 2005 Cited by PubMed: 15723805DOI: 10.1016/j.immuni.2004.12.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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