1TZG
Crystal structure of HIV-1 neutralizing human Fab 4E10 in complex with a 13-residue peptide containing the 4E10 epitope on gp41
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL L 701 |
| Chain | Residue |
| H | PHE174 |
| L | THR178 |
| L | HOH774 |
| H | PRO175 |
| H | VAL177 |
| H | SER186 |
| H | LEU187 |
| H | SER188 |
| L | SER162 |
| L | SER176 |
| L | SER177 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL L 702 |
| Chain | Residue |
| H | GLY164 |
| L | ARG61 |
| L | GLU81 |
| L | HOH770 |
| L | HOH813 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL L 703 |
| Chain | Residue |
| H | PRO214 |
| L | PRO8 |
| L | GLY9 |
| L | THR10 |
| L | HOH761 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR206-HIS212 | |
| L | TYR192-HIS198 |
