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7JOV
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BU of 7jov by Molmil
CRYSTAL STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE 2 (ROCK2) IN COMPLEX WITH A PHENYLPYRAZOLE AMIDE INHIBITOR
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, N-[(1S)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1H-pyrazol-4-yl)benzamide, ...
Authors:Muckelbauer, J.K.
Deposit date:2020-08-07
Release date:2020-09-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies.
Bioorg.Med.Chem.Lett., 30, 2020
1KX8
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BU of 1kx8 by Molmil
Antennal Chemosensory Protein A6 from Mamestra brassicae, tetragonal form
Descriptor: CHEMOSENSORY PROTEIN A6
Authors:Lartigue, A, Campanacci, V, Roussel, A, Larsson, A.M, Jones, T.A, Tegoni, M, Cambillau, C.
Deposit date:2002-01-31
Release date:2002-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-Ray Structure and Ligand Binding Study of a Chemosensory Protein
J.Biol.Chem., 277, 2002
6JBI
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BU of 6jbi by Molmil
Structure of Tps1 apo structure
Descriptor: Trehalose-6-phosphate synthase
Authors:Wang, S, Zhao, Y, Yi, L, Wang, D, Liu, J.
Deposit date:2019-01-25
Release date:2019-12-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1.
Biochem.J., 476, 2019
6JAK
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BU of 6jak by Molmil
OtsA apo structure
Descriptor: Trehalose-6-phosphate synthase
Authors:Wang, S, Zhao, Y, Wang, D, Liu, J.
Deposit date:2019-01-24
Release date:2019-12-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1.
Biochem.J., 476, 2019
7MC4
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BU of 7mc4 by Molmil
Crystal structure of a single-chain E/F type bilin lyase-isomerase MpeQ
Descriptor: Bilin Lyase-Isomerase
Authors:Yang, X, Kumarapperuma, I.
Deposit date:2021-04-01
Release date:2022-02-23
Last modified:2022-04-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure and molecular mechanism of an E/F type bilin lyase-isomerase.
Structure, 30, 2022
6J0Q
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BU of 6j0q by Molmil
Crystal structure of P domain from GII.11 swine norovirus
Descriptor: VP1 capsid protein
Authors:Chen, Y.
Deposit date:2018-12-25
Release date:2019-11-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of host ligand specificity change of GII porcine noroviruses from their closely related GII human noroviruses.
Emerg Microbes Infect, 8, 2019
4LN2
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BU of 4ln2 by Molmil
The second SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin
Descriptor: Sorbin and SH3 domain-containing protein 1, proline rich peptide
Authors:Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
Deposit date:2013-07-11
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
5NDF
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BU of 5ndf by Molmil
Small-molecule inhibition of ppGalNAc-Ts selectively reduces mucin-type O-glycosylation
Descriptor: 1,2-ETHANEDIOL, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, MANGANESE (II) ION, ...
Authors:Hurtado-Guerrero, R, De las Rivas, M.
Deposit date:2017-03-08
Release date:2017-11-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The small molecule luteolin inhibits N-acetyl-alpha-galactosaminyltransferases and reduces mucin-type O-glycosylation of amyloid precursor protein.
J. Biol. Chem., 292, 2017
7TIK
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BU of 7tik by Molmil
Structure of the SARS-CoV-2 Omicron spike post-fusion bundle
Descriptor: Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-01-13
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
6JBW
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BU of 6jbw by Molmil
Structure of Tps1/UDP complex
Descriptor: Trehalose-6-phosphate synthase, URIDINE-5'-DIPHOSPHATE
Authors:Wang, S, Zhao, Y, Wang, D, Liu, J.
Deposit date:2019-01-26
Release date:2019-12-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1.
Biochem.J., 476, 2019
7R40
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BU of 7r40 by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 87G7 heavy chain variable region, ...
Authors:Hurdiss, D.L.
Deposit date:2022-02-08
Release date:2022-04-20
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern.
Sci Immunol, 7, 2022
1AUV
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BU of 1auv by Molmil
STRUCTURE OF THE C DOMAIN OF SYNAPSIN IA FROM BOVINE BRAIN
Descriptor: SYNAPSIN IA
Authors:Esser, L, Wang, C, Deisenhofer, J.
Deposit date:1997-09-02
Release date:1998-03-18
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Synapsin I is structurally similar to ATP-utilizing enzymes.
EMBO J., 17, 1998
2OZT
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BU of 2ozt by Molmil
Crystal structure of O-succinylbenzoate synthase from Thermosynechococcus elongatus BP-1
Descriptor: PHOSPHATE ION, SODIUM ION, Tlr1174 protein
Authors:Malashkevich, V.N, Bonanno, J, Toro, R, Sauder, J.M, Schwinn, K.D, Bain, K.T, Adams, J.M, Reyes, C, Rooney, I, Gheyi, T, Wasserman, S.R, Emtage, S, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-02-27
Release date:2007-03-13
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.
Proc.Natl.Acad.Sci.USA, 111, 2014
2OLA
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BU of 2ola by Molmil
Crystal structure of O-succinylbenzoic acid synthetase from Staphylococcus aureus, cubic crystal form
Descriptor: O-succinylbenzoic acid synthetase
Authors:Patskovsky, Y, Sauder, J.M, Ozyurt, S, Wasserman, S.R, Smith, D, Dickey, M, Maletic, M, Reyes, C, Gheyi, T, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-01-18
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.
Proc.Natl.Acad.Sci.USA, 111, 2014
3CAW
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BU of 3caw by Molmil
Crystal structure of o-succinylbenzoate synthase from Bdellovibrio bacteriovorus liganded with Mg
Descriptor: MAGNESIUM ION, o-succinylbenzoate synthase
Authors:Fedorov, A.A, Fedorov, E.V, Sakai, A, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2008-02-20
Release date:2008-03-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.
Proc.Natl.Acad.Sci.USA, 111, 2014
7U6R
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BU of 7u6r by Molmil
Cryo-EM structure of PDF-2180 Spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PDF-2180 Spike glycoprotein
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-03-05
Release date:2022-11-30
Last modified:2023-01-04
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Close relatives of MERS-CoV in bats use ACE2 as their functional receptors.
Nature, 612, 2022
5XSJ
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BU of 5xsj by Molmil
XylFII-LytSN complex
Descriptor: Periplasmic binding protein/LacI transcriptional regulator, Signal transduction histidine kinase, LytS, ...
Authors:Li, J.X, Wang, C.Y, Zhang, P.
Deposit date:2017-06-14
Release date:2017-08-02
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5HXL
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BU of 5hxl by Molmil
Structure based function annotation of a hypothetical protein MGG_01005 related to the development of rice blast fungus
Descriptor: dynein light chain Tctex-1
Authors:Liu, J, Huang, J, Li, G, Peng, Y.
Deposit date:2016-01-31
Release date:2017-02-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure based function-annotation of hypothetical protein MGG_01005 from Magnaporthe oryzae reveals it is the dynein light chain orthologue of dynlt1/3.
Sci Rep, 8, 2018
5XSD
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BU of 5xsd by Molmil
XylFII-LytSN complex mutant - D103A
Descriptor: Periplasmic binding protein/LacI transcriptional regulator, Signal transduction histidine kinase, LytS
Authors:Li, J.X, Wang, C.Y, Zhang, P.
Deposit date:2017-06-13
Release date:2017-08-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XSS
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BU of 5xss by Molmil
XylFII molecule
Descriptor: Periplasmic binding protein/LacI transcriptional regulator, beta-D-xylopyranose
Authors:Li, J.X, Wang, C.Y, Zhang, P.
Deposit date:2017-06-15
Release date:2017-08-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5HYC
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BU of 5hyc by Molmil
Structure based function annotation of a hypothetical protein MGG_01005 related to the development of rice blast fungus
Descriptor: Cytoplasmic dynein 1 intermediate chain 2, Uncharacterized protein
Authors:Liu, J, Li, G, Huang, J, Peng, Y.-l.
Deposit date:2016-02-01
Release date:2017-02-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure based function-annotation of hypothetical protein MGG_01005 from Magnaporthe oryzae reveals it is the dynein light chain orthologue of dynlt1/3.
Sci Rep, 8, 2018
1WUE
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BU of 1wue by Molmil
Crystal structure of protein GI:29375081, unknown member of enolase superfamily from enterococcus faecalis V583
Descriptor: mandelate racemase/muconate lactonizing enzyme family protein
Authors:Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-12-05
Release date:2004-12-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family
Proc.Natl.Acad.Sci.USA, 111, 2014
1WUF
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BU of 1wuf by Molmil
Crystal structure of protein GI:16801725, member of Enolase superfamily from Listeria innocua Clip11262
Descriptor: MAGNESIUM ION, hypothetical protein lin2664
Authors:Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-12-07
Release date:2004-12-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family
Proc.Natl.Acad.Sci.USA, 111, 2014
6UVB
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BU of 6uvb by Molmil
Crystal structure of far-red-light absorbing cyanobacteriochrome at 100K
Descriptor: Multi-sensor signal transduction histidine kinase, PHYCOCYANOBILIN
Authors:Yang, X, Ren, Z, Bandara, S.
Deposit date:2019-11-01
Release date:2020-11-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a far-red-sensing cyanobacteriochrome reveals an atypical bilin conformation and spectral tuning mechanism.
Proc.Natl.Acad.Sci.USA, 118, 2021
1I38
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BU of 1i38 by Molmil
CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN T877A MUTANT COMPLEX WITH DIHYDROTESTOSTERONE
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, ANDROGEN RECEPTOR
Authors:Sack, J.S.
Deposit date:2001-02-13
Release date:2001-03-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone.
Proc.Natl.Acad.Sci.USA, 98, 2001

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