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6ZM2
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BU of 6zm2 by Molmil
Crystal structure of the DEAH-box ATPase Prp2 in complex with ADP-BeF3 and ssRNA
Descriptor: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hamann, F, Ficner, R.
Deposit date:2020-07-01
Release date:2021-04-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of Prp2 bound to RNA and ADP-BeF 3 - reveals structural features important for RNA unwinding by DEAH-box ATPases.
Acta Crystallogr D Struct Biol, 77, 2021
2GBS
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BU of 2gbs by Molmil
NMR structure of Rpa0253 from Rhodopseudomonas palustris. Northeast structural genomics consortium target RpR3
Descriptor: Hypothetical protein Rpa0253
Authors:Ramelot, T.A, Cort, J.R, Conover, K, Chen, Y, Ma, L.C, Ciano, M, Xiao, R, Acton, T.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-03-11
Release date:2006-04-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural genomics reveals EVE as a new ASCH/PUA-related domain.
Proteins, 75, 2009
8TC9
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BU of 8tc9 by Molmil
Human asparaginyl-tRNA synthetase bound to OSM-S-106
Descriptor: Asparagine--tRNA ligase, cytoplasmic, GLYCEROL, ...
Authors:Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W.
Deposit date:2023-06-30
Release date:2024-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
8TC8
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BU of 8tc8 by Molmil
Human asparaginyl-tRNA synthetase bound to adenosine 5'-sulfamate
Descriptor: 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, Asparagine--tRNA ligase, cytoplasmic, ...
Authors:Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W.
Deposit date:2023-06-30
Release date:2024-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
8TC7
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BU of 8tc7 by Molmil
Human asparaginyl-tRNA synthetase, apo form
Descriptor: Asparagine--tRNA ligase, cytoplasmic, CHLORIDE ION, ...
Authors:Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W.
Deposit date:2023-06-30
Release date:2024-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
6ZYT
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BU of 6zyt by Molmil
Monomeric streptavidin with a conjugated biotinylated pyrrolidine
Descriptor: 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-((S)-pyrrolidin-3-yl)pentanamide, SULFATE ION, Streptavidin/Rhizavidin Hybrid
Authors:Nodling, A.R, Lipka-Lloyd, M, Tsai, Y.H, Rizkallah, P, Luk, L.Y.P, Jin, Y.
Deposit date:2020-08-03
Release date:2021-08-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The role of streptavidin and its variants in catalysis by biotinylated secondary amines.
Org.Biomol.Chem., 19, 2021
7JQ8
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BU of 7jq8 by Molmil
Solution NMR structure of human Brd3 ET domain
Descriptor: Bromodomain-containing protein 3, Integrase peptide
Authors:Aiyer, S, Swapna, G.V.T, Roth, J.M, Montelione, G.T.
Deposit date:2020-08-10
Release date:2021-06-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins.
Structure, 29, 2021
7JMY
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BU of 7jmy by Molmil
Solution NMR structure of human Brd3 ET domain
Descriptor: Bromodomain-containing protein 3
Authors:Aiyer, S, Swapna, G.V.T, Roth, J.M, Montelione, G.T.
Deposit date:2020-08-03
Release date:2021-03-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins.
Structure, 29, 2021
8U5G
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BU of 8u5g by Molmil
Crystal structure of the co-expressed SDS22:PP1:I3 complex
Descriptor: E3 ubiquitin-protein ligase PPP1R11, FE (III) ION, PHOSPHATE ION, ...
Authors:Choy, M.S, Peti, W, Page, R.
Deposit date:2023-09-12
Release date:2023-12-06
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The SDS22:PP1:I3 complex: SDS22 binding to PP1 loosens the active site metal to prime metal exchange.
J.Biol.Chem., 300, 2023
7JYN
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BU of 7jyn by Molmil
Solution NMR structure of human Brd3 ET complexed with NSD3(148-184) peptide
Descriptor: Bromodomain-containing protein 3, Histone-lysine N-methyltransferase NSD3
Authors:Aiyer, S, Swapna, G.V.T, Roth, M.J, Montelione, G.T.
Deposit date:2020-08-31
Release date:2021-06-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins.
Structure, 29, 2021
8UMO
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BU of 8umo by Molmil
Murine CD94-NKG2A receptor in complex with Qa-1b presenting AMAPRTLLL
Descriptor: BROMIDE ION, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:MacLachlan, B.J, Rossjohn, J, Vivian, J.P.
Deposit date:2023-10-18
Release date:2024-01-17
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the murine CD94-NKG2A receptor in complex with Qa-1 b presenting an MHC-I leader peptide.
Febs J., 291, 2024
8TUB
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BU of 8tub by Molmil
HLA B7:02 with HPNGYKSLSTL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Littler, D.R, Rossjohn, J, Chaurasia, P, Petersen, J.
Deposit date:2023-08-16
Release date:2024-03-13
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CD8 + T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age.
Nat Commun, 15, 2024
8TUH
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BU of 8tuh by Molmil
HLA B7:02 with RPIIRPATL
Descriptor: 1,2-ETHANEDIOL, ARG-PRO-ILE-ILE-ARG-PRO-ALA-THR-LEU, Beta-2-microglobulin, ...
Authors:Littler, D.R, Rossjohn, J, Chaurasia, P, Petersen, J.
Deposit date:2023-08-16
Release date:2024-03-13
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.200106 Å)
Cite:CD8 + T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age.
Nat Commun, 15, 2024
8TWQ
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BU of 8twq by Molmil
Structure of bacteriophage lambda RexA protein
Descriptor: CADMIUM ION, Protein rexA, SULFATE ION
Authors:Adams, M.C, Chappie, J.S, Schiltz, C.J.
Deposit date:2023-08-21
Release date:2024-04-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The crystal structure of bacteriophage lambda RexA provides novel insights into the DNA binding properties of Rex-like phage exclusion proteins.
Nucleic Acids Res., 52, 2024
6ZOZ
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BU of 6zoz by Molmil
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Locked State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZWC
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BU of 6zwc by Molmil
Z-SBTub2 photoswitch bound to tubulin-DARPin D1 complex
Descriptor: 2-[2-(3,4,5-trimethoxyphenyl)ethyl]-1,3-benzothiazole, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wranik, M, Weinert, T, Olieric, N, Gao, L, Kraus, Y.C.M, Bingham, R, Ntouliou, E, Ahlfeld, J, Thorn-Seshold, O, Steinmetz, M.O, Standfuss, J.
Deposit date:2020-07-28
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton.
Cell Chem Biol, 28, 2021
6ZOY
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BU of 6zoy by Molmil
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZWB
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BU of 6zwb by Molmil
Z-SBTub3 photoswitch bound to tubulin-DARPin D1 complex
Descriptor: 5-[2-(1,3-benzothiazol-2-yl)ethyl]-2-methoxy-phenol, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wranik, M, Weinert, T, Olieric, N, Gao, L, Kraus, Y.C.M, Bingham, R, Ntouliou, E, Ahlfeld, J, Thorn-Seshold, O, Steinmetz, M.O, Standfuss, J.
Deposit date:2020-07-28
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.747 Å)
Cite:A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton.
Cell Chem Biol, 28, 2021
6ZP0
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BU of 6zp0 by Molmil
Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZP1
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BU of 6zp1 by Molmil
Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZOX
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BU of 6zox by Molmil
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZP2
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BU of 6zp2 by Molmil
Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Locked State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
8YD8
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BU of 8yd8 by Molmil
Structure of FADD/Caspase-8/cFLIP death effector domain assembly
Descriptor: CASP8 and FADD-like apoptosis regulator subunit p43, Caspase-8, FAS-associated death domain protein
Authors:Lin, S.-C, Yang, C.-Y.
Deposit date:2024-02-19
Release date:2024-05-15
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis.
Nat Commun, 15, 2024
8YD7
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BU of 8yd7 by Molmil
Structure of FADD/Caspase-8/cFLIP death effector domain assembly
Descriptor: CASP8 and FADD-like apoptosis regulator subunit p12, Caspase-8, FAS-associated death domain protein, ...
Authors:Lin, S.-C, Yang, C.-Y.
Deposit date:2024-02-19
Release date:2024-05-15
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis.
Nat Commun, 15, 2024
7KJP
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BU of 7kjp by Molmil
Disulfide Stabilized Norovirus GI.1 VLP Shell Region
Descriptor: Capsid protein VP1
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-10-26
Release date:2020-12-02
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes.
NPJ Vaccines, 5, 2020

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