8U5G

Crystal structure of the co-expressed SDS22:PP1:I3 complex

Summary for 8U5G

• Entry DOI: 10.2210/pdb8u5g/pdb
• Descriptor: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, Protein phosphatase 1 regulatory subunit 7, E3 ubiquitin-protein ligase PPP1R11, ... (6 entities in total)
• Functional Keywords: phosphatase, inhibitor, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 76622.30

Authors

Choy, M.S.,Peti, W.,Page, R. (deposition date: 2023-09-12, release date: 2023-12-06, Last modification date: 2024-01-03)

• Primary citation: Choy, M.S.,Srivastava, G.,Robinson, L.C.,Tatchell, K.,Page, R.,Peti, W.; The SDS22:PP1:I3 complex: SDS22 binding to PP1 loosens the active site metal to prime metal exchange.; J.Biol.Chem., 300:105515-105515, 2023; PubMed: 38042495; DOI: 10.1016/j.jbc.2023.105515

Experimental method

X-RAY DIFFRACTION (3.2 Å)