5ILF
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![BU of 5ilf by Molmil](/molmil-images/mine/5ilf) | The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and compound 4, a platin(II) compound containing a O, S bidentate ligand | Descriptor: | ACETATE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2016-03-04 | Release date: | 2016-12-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Platinum(ii) O,S complexes as potential metallodrugs against Cisplatin resistance. Dalton Trans, 45, 2016
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4Z46
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4ZFP
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7QWH
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![BU of 7qwh by Molmil](/molmil-images/mine/7qwh) | X-ray structure of the adduct formed upon reaction of a vanadium hydroxyquinoline complex with RNase A | Descriptor: | 2,2-bis($l^{1}-oxidanyl)-3-oxa-1$l^{4}-aza-2$l^{4}-vanadatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaene, Ribonuclease pancreatic | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2022-01-25 | Release date: | 2023-02-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.573 Å) | Cite: | Interaction of VIVO-8-hydroxyquinoline species with RNase A: the effect of metal ligands in the protein adduct stabilization Inorg Chem Front, 2023
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4Z3M
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![BU of 4z3m by Molmil](/molmil-images/mine/4z3m) | X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) Complex with S,O Bidentate Ligands (9b) | Descriptor: | 1,2-ETHANEDIOL, 3-[2-chloranyl-2-[dimethyl(oxidanyl)-{4}-sulfanyl]-4-ethylsulfanyl-1-oxa-3{3}-thia-2{4}-platinacyclohexa-3,5-dien-6-yl]phenol, DIMETHYL SULFOXIDE, ... | Authors: | Merlino, A. | Deposit date: | 2015-03-31 | Release date: | 2015-09-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding. Inorg.Chem., 54, 2015
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4Z41
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![BU of 4z41 by Molmil](/molmil-images/mine/4z41) | X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) Compound with a S,O Bidentate Ligand (9a=Chloro-(1-(3'-hydroxy)-3-(methylthio)-3-thioxo-prop-1-en-1-olate-O,S)-(dimethylsulfoxide-S)-platinum(II)) | Descriptor: | 1,2-ETHANEDIOL, 3-[2-chloranyl-2-[dimethyl(oxidanyl)-{4}-sulfanyl]-4-ethylsulfanyl-1-oxa-3{3}-thia-2{4}-platinacyclohexa-3,5-dien-6-yl]phenol, DIMETHYL SULFOXIDE, ... | Authors: | Merlino, A. | Deposit date: | 2015-04-01 | Release date: | 2015-09-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding. Inorg.Chem., 54, 2015
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4ZEE
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6QE9
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![BU of 6qe9 by Molmil](/molmil-images/mine/6qe9) | The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands | Descriptor: | Ribonuclease pancreatic, SULFATE ION, pentacoordinate Pt(II) compound | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2019-01-07 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Reaction with Proteins of a Five-Coordinate Platinum(II) Compound. Int J Mol Sci, 20, 2019
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6QEA
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![BU of 6qea by Molmil](/molmil-images/mine/6qea) | The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands | Descriptor: | DIMETHYL SULFOXIDE, Lysozyme C, NITRATE ION, ... | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2019-01-07 | Release date: | 2019-03-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Reaction with Proteins of a Five-Coordinate Platinum(II) Compound. Int J Mol Sci, 20, 2019
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6GOH
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![BU of 6goh by Molmil](/molmil-images/mine/6goh) | X-ray structure of the adduct formed upon reaction of lysozyme with a Pt(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated sulphonate side chain | Descriptor: | CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2018-06-01 | Release date: | 2018-07-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Exploring the interactions between model proteins and Pd(ii) or Pt(ii) compounds bearing charged N,N-pyridylbenzimidazole bidentate ligands by X-ray crystallography. Dalton Trans, 47, 2018
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6GOI
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![BU of 6goi by Molmil](/molmil-images/mine/6goi) | X-ray structure of the adduct formed upon reaction of lysozyme with a Pd(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated triphenylphosphonium cation | Descriptor: | CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2018-06-01 | Release date: | 2018-07-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Exploring the interactions between model proteins and Pd(ii) or Pt(ii) compounds bearing charged N,N-pyridylbenzimidazole bidentate ligands by X-ray crystallography. Dalton Trans, 47, 2018
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6GOB
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![BU of 6gob by Molmil](/molmil-images/mine/6gob) | X-ray structure of the adduct formed upon reaction of lysozyme with a Pd(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated sulphonate side chain | Descriptor: | CHLORIDE ION, Lysozyme C, N,N-pyridylbenzimidazole derivative-Pd complex, ... | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2018-06-01 | Release date: | 2018-07-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Exploring the interactions between model proteins and Pd(ii) or Pt(ii) compounds bearing charged N,N-pyridylbenzimidazole bidentate ligands by X-ray crystallography. Dalton Trans, 47, 2018
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6GOJ
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![BU of 6goj by Molmil](/molmil-images/mine/6goj) | X-ray structure of the adduct formed upon reaction of lysozyme with a Pt(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated triphenylphosphonium cation | Descriptor: | CHLORIDE ION, Lysozyme C, NITRATE ION, ... | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2018-06-01 | Release date: | 2018-07-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Exploring the interactions between model proteins and Pd(ii) or Pt(ii) compounds bearing charged N,N-pyridylbenzimidazole bidentate ligands by X-ray crystallography. Dalton Trans, 47, 2018
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6GOK
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![BU of 6gok by Molmil](/molmil-images/mine/6gok) | X-ray structure of the adduct formed upon reaction of bovine pancreatic ribonuclease with a Pd(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated sulphonate side chain | Descriptor: | N,N-pyridylbenzimidazole derivative-Pd complex, PALLADIUM ION, Ribonuclease pancreatic | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2018-06-01 | Release date: | 2018-07-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Exploring the interactions between model proteins and Pd(ii) or Pt(ii) compounds bearing charged N,N-pyridylbenzimidazole bidentate ligands by X-ray crystallography. Dalton Trans, 47, 2018
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4OTU
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4OTT
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![BU of 4ott by Molmil](/molmil-images/mine/4ott) | Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis. | Descriptor: | Gamma glutamyl transpeptidase, Gamma-glutamyltranspeptidase, MAGNESIUM ION | Authors: | Merlino, A. | Deposit date: | 2014-02-14 | Release date: | 2014-07-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Low resolution X-ray structure of gamma-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion. Biochim.Biophys.Acta, 1844, 2014
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4MR1
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4OOO
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4OOT
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11BG
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![BU of 11bg by Molmil](/molmil-images/mine/11bg) | A POTENTIAL ALLOSTERIC SUBSITE GENERATED BY DOMAIN SWAPPING IN BOVINE SEMINAL RIBONUCLEASE | Descriptor: | PROTEIN (BOVINE SEMINAL RIBONUCLEASE), SULFATE ION, URIDYLYL-2'-5'-PHOSPHO-GUANOSINE | Authors: | Vitagliano, L, Adinolfi, S, Sica, F, Merlino, A, Zagari, A, Mazzarella, L. | Deposit date: | 1999-03-11 | Release date: | 1999-11-05 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease. J.Mol.Biol., 293, 1999
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1JVT
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1JVU
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![BU of 1jvu by Molmil](/molmil-images/mine/1jvu) | CRYSTAL STRUCTURE OF RIBONUCLEASE A (COMPLEXED FORM) | Descriptor: | CYTIDINE-2'-MONOPHOSPHATE, RIBONUCLEASE A | Authors: | Vitagliano, L, Merlino, A, Zagari, A, Mazzarella, L. | Deposit date: | 2001-08-31 | Release date: | 2002-06-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Reversible Substrate-Induced Domain Motions in Ribonuclease A Proteins, 46, 2002
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1TQ9
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![BU of 1tq9 by Molmil](/molmil-images/mine/1tq9) | Non-covalent swapped dimer of Bovine Seminal Ribonuclease in complex with 2'-DEOXYCYTIDINE-2'-DEOXYADENOSINE-3',5'-MONOPHOSPHATE | Descriptor: | 2'-DEOXYCYTIDINE-2'-DEOXYADENOSINE-3',5'-MONOPHOSPHATE, Ribonuclease, seminal | Authors: | Sica, F, Di Fiore, A, Merlino, A, Mazzarella, L. | Deposit date: | 2004-06-17 | Release date: | 2004-09-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and Stability of the Non-covalent Swapped Dimer of Bovine Seminal Ribonuclease: AN ENZYME TAILORED TO EVADE RIBONUCLEASE PROTEIN INHIBITOR J.Biol.Chem., 279, 2004
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8A2L
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8A5N
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