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8E8H
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BU of 8e8h by Molmil
Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 300s
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2022-08-25
Release date:2023-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity.
J.Biol.Chem., 299, 2023
3LGP
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BU of 3lgp by Molmil
Crystal structure of catalytic domain of tace with benzimidazolyl-thienyl-tartrate based inhibitor
Descriptor: (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-{[2-(trifluoromethyl)-1H-benzimidazol-1-yl]methyl}thiophen-2-yl)methyl]butanamide, Disintegrin and metalloproteinase domain-containing protein 17, ZINC ION
Authors:Orth, P.
Deposit date:2010-01-21
Release date:2010-07-28
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and activity relationships of tartrate-based TACE inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3LE9
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BU of 3le9 by Molmil
Crystal structure of the catalytic domain of TACE with Indazolinone-phenyl-hydantoin inhibitor
Descriptor: (5R)-5-[(5-methoxy-3-oxo-1,3-dihydro-2H-indazol-2-yl)methyl]-5-phenylimidazolidine-2,4-dione, Disintegrin and metalloproteinase domain-containing protein 17, ISOPROPYL ALCOHOL, ...
Authors:Orth, P.
Deposit date:2010-01-14
Release date:2010-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Biaryl substituted hydantoin compounds as TACE inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
1QH4
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BU of 1qh4 by Molmil
CRYSTAL STRUCTURE OF CHICKEN BRAIN-TYPE CREATINE KINASE AT 1.41 ANGSTROM RESOLUTION
Descriptor: ACETATE ION, CALCIUM ION, CREATINE KINASE
Authors:Eder, M, Schlattner, U, Becker, A, Wallimann, T, Kabsch, W, Fritz-Wolf, K.
Deposit date:1999-05-11
Release date:1999-11-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal structure of brain-type creatine kinase at 1.41 A resolution.
Protein Sci., 8, 1999
1SD0
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BU of 1sd0 by Molmil
Structure of arginine kinase C271A mutant
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ARGININE, Arginine kinase, ...
Authors:Gattis, J.L, Ruben, E, Fenley, M.O, Ellington, W.R, Chapman, M.S.
Deposit date:2004-02-12
Release date:2004-07-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The active site cysteine of arginine kinase: structural and functional analysis of partially active mutants
Biochemistry, 43, 2004
6IRR
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BU of 6irr by Molmil
Solution structure of DISC1/ATF4 complex
Descriptor: Disrupted in schizophrenia 1 homolog,Cyclic AMP-dependent transcription factor ATF-4
Authors:Ye, F, Yu, C, Zhang, M.
Deposit date:2018-11-14
Release date:2019-09-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders.
Mol. Psychiatry, 2019
6K0R
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BU of 6k0r by Molmil
Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin
Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Zhang, W, Chen, L, Li, W, Ju, D, Huang, N, Zhang, E.
Deposit date:2019-05-07
Release date:2020-05-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals.
Sci Transl Med, 12, 2020
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