7SN1
Structure of human SARS-CoV-2 neutralizing antibody C1C-A3 Fab
Summary for 7SN1
Entry DOI | 10.2210/pdb7sn1/pdb |
Descriptor | neutralizing antibody C1C-A3 Fab heavy chain, neutralizing antibody C1C-A3 Fab light chain (3 entities in total) |
Functional Keywords | covid-19, sars-cov-2, neutralizing antibody, neutralization escape, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 52918.71 |
Authors | Pan, J.,Abraham, J.,Clark, S. (deposition date: 2021-10-27, release date: 2021-12-08, Last modification date: 2023-10-18) |
Primary citation | Nabel, K.G.,Clark, S.A.,Shankar, S.,Pan, J.,Clark, L.E.,Yang, P.,Coscia, A.,McKay, L.G.A.,Varnum, H.H.,Brusic, V.,Tolan, N.V.,Zhou, G.,Desjardins, M.,Turbett, S.E.,Kanjilal, S.,Sherman, A.C.,Dighe, A.,LaRocque, R.C.,Ryan, E.T.,Tylek, C.,Cohen-Solal, J.F.,Darcy, A.T.,Tavella, D.,Clabbers, A.,Fan, Y.,Griffiths, A.,Correia, I.R.,Seagal, J.,Baden, L.R.,Charles, R.C.,Abraham, J. Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science, 375:eabl6251-eabl6251, 2022 Cited by PubMed: 34855508DOI: 10.1126/science.abl6251 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.467 Å) |
Structure validation
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