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Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor:	ANTI-HIV ANTIBODY DH570.mut58 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570.mut58 FAB LIGHT CHAIN
Authors:	Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
Deposit date:	2015-08-24
Release date:	2016-05-11
Last modified:	2019-12-11
Method:	X-RAY DIFFRACTION (1.699 Å)
Cite:	Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016

5DD3

Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor:	ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
Authors:	Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
Deposit date:	2015-08-24
Release date:	2016-05-11
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.797 Å)
Cite:	Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016

5DD5

Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor:	ANTI-HIV ANTIBODY DH570.9 FAB HEAVY CHAIN
Authors:	Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
Deposit date:	2015-08-24
Release date:	2016-05-11
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016

8F5I

SARS-CoV-2 S2 helix epitope scaffold bound by antibody DH1057.1
Descriptor:	DH1057.1 HC, DH1057.1 LC, Specialized acyl carrier protein, ...
Authors:	Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L.
Deposit date:	2022-11-14
Release date:	2023-10-11
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Engineered immunogens to elicit antibodies against conserved coronavirus epitopes. Nat Commun, 14, 2023

8F5H

SARS-CoV-2 S2 helix epitope scaffold
Descriptor:	S2hlx_EX_19
Authors:	Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L.
Deposit date:	2022-11-14
Release date:	2023-10-11
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Engineered immunogens to elicit antibodies against conserved coronavirus epitopes. Nat Commun, 14, 2023

7N0X

Rhesusized RV144 DH827 Fab bound to HIV-1 Env V2 peptide
Descriptor:	DI(HYDROXYETHYL)ETHER, Glycoprotein 120, Rhesusized RV144 DH827 heavy chain Fab fragment, ...
Authors:	Tolbert, W.D, Pazgier, M.
Deposit date:	2021-05-26
Release date:	2022-04-06
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s. Front Immunol, 12, 2021

7N28

Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 Env
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody heavy chain, ...
Authors:	Zhou, T, Gao, F.
Deposit date:	2021-05-28
Release date:	2022-04-06
Last modified:	2022-06-22
Method:	ELECTRON MICROSCOPY (4.2 Å)
Cite:	Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2. Adv Sci, 9, 2022

7N8Q

Rhesusized RV305 DH677.3 Fab bound to Clade A/E 93TH057 HIV-1 gp120 core.
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, M48U1 CD4 MIMETIC PEPTIDE, Rhesusized DH677.3 FAB HEAVY CHAIN, ...
Authors:	Tolbert, W.D, Pazgier, M.
Deposit date:	2021-06-15
Release date:	2022-04-06
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s. Front Immunol, 12, 2021

6VBP

Crystal structure of anti-HIV-1 antibody DH815 bound to gp120 V2 peptide
Descriptor:	CHLORIDE ION, DH815 heavy chain, DH815 light chain, ...
Authors:	Janus, B.M, Ofek, G.
Deposit date:	2019-12-19
Release date:	2020-02-12
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.298 Å)
Cite:	HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions. JCI Insight, 5, 2020

6VBQ

Crystal structure of anti-HIV-1 antibody DH822 bound to gp120 V2 peptide
Descriptor:	DH822 heavy chain, DH822 light chain, Envelope glycoprotein gp160
Authors:	Janus, B.M, Ofek, G.
Deposit date:	2019-12-19
Release date:	2020-02-12
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.116 Å)
Cite:	HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions. JCI Insight, 5, 2020

6VBO

Crystal structure of anti-HIV-1 antibody DH813 bound to gp120 V2 peptide
Descriptor:	DH813 heavy chain, DH813 light chain, Envelope glycoprotein gp160
Authors:	Janus, B.M, Ofek, G.
Deposit date:	2019-12-19
Release date:	2020-02-12
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.683 Å)
Cite:	HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions. JCI Insight, 5, 2020

7THT

CryoEM structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1042 heavy chain, ...
Authors:	Manne, K, May, A, Acharya, P.
Deposit date:	2022-01-12
Release date:	2022-02-16
Last modified:	2023-04-12
Method:	ELECTRON MICROSCOPY (3.42 Å)
Cite:	Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022

7TL9

SARS-CoV-2 Omicron 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Stalls, V, Acharya, P.
Deposit date:	2022-01-18
Release date:	2022-02-23
Last modified:	2023-04-12
Method:	ELECTRON MICROSCOPY (3.5 Å)
Cite:	Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022

7LD1

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 heavy chain, ...
Authors:	Manne, K, Acharya, P.
Deposit date:	2021-01-12
Release date:	2021-01-27
Last modified:	2021-08-18
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LCN

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1050.1
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1050.1 heavy chain, ...
Authors:	Manne, K, Acharya, P.
Deposit date:	2021-01-11
Release date:	2021-01-27
Last modified:	2021-08-18
Method:	ELECTRON MICROSCOPY (3.35 Å)
Cite:	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7TEI

SARS-CoV-2 Omicron 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Stalls, V, Acharya, P.
Deposit date:	2022-01-05
Release date:	2022-02-16
Last modified:	2023-04-12
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022

7TF8

SARS-CoV-2 Omicron 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Stalls, V, Acharya, P.
Deposit date:	2022-01-06
Release date:	2022-02-16
Last modified:	2023-04-12
Method:	ELECTRON MICROSCOPY (3.36 Å)
Cite:	Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022

7TL1

SARS-CoV-2 Omicron 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Stalls, V, Acharya, P.
Deposit date:	2022-01-18
Release date:	2022-02-23
Last modified:	2023-04-12
Method:	ELECTRON MICROSCOPY (3.5 Å)
Cite:	Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022

7LAB

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1052
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1052 heavy chain, ...
Authors:	Manne, K, Acharya, P.
Deposit date:	2021-01-06
Release date:	2021-03-10
Last modified:	2021-08-18
Method:	ELECTRON MICROSCOPY (2.97 Å)
Cite:	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LAA

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1041
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1041 heavy chain, ...
Authors:	Manne, K, Acharya, P.
Deposit date:	2021-01-06
Release date:	2021-03-17
Last modified:	2021-08-18
Method:	ELECTRON MICROSCOPY (3.42 Å)
Cite:	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LYK

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 2-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.65 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYQ

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.34 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYL

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the RBD-down conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.72 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYO

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (3.32 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYP

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Gobeil, S, Acharya, P.
Deposit date:	2021-03-07
Release date:	2021-03-31
Last modified:	2022-12-07
Method:	ELECTRON MICROSCOPY (4.05 Å)
Cite:	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

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