2CYC
| Crystal structure of Tyrosyl-tRNA Synthetase complexed with L-tyrosine from Pyrococcus horikoshii | Descriptor: | TYROSINE, tyrosyl-tRNA synthetase | Authors: | Kuratani, M, Sakai, H, Takahashi, M, Yanagisawa, T, Kobayashi, T, Sakamoto, K, Terada, T, Shirouzu, M, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-06 | Release date: | 2005-11-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of Tyrosyl-tRNA Synthetases from Archaea J.Mol.Biol., 355, 2006
|
|
2CZJ
| Crystal structure of the tRNA domain of tmRNA from Thermus thermophilus HB8 | Descriptor: | SsrA-binding protein, tmRNA (63-MER) | Authors: | Bessho, Y, Shibata, R, Sekine, S, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-13 | Release date: | 2006-10-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2CXI
| |
2D5A
| |
2D59
| |
2ZR3
| |
2ZR2
| Crystal structure of seryl-tRNA synthetase from Pyrococcus horikoshii complexed with ATP | Descriptor: | ADENOSINE MONOPHOSPHATE, SULFATE ION, Seryl-tRNA synthetase | Authors: | Itoh, Y, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-08-22 | Release date: | 2008-09-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystallographic and mutational studies of seryl-tRNA synthetase from the archaeon Pyrococcus horikoshii. Rna Biol., 5, 2008
|
|
3A98
| Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1 | Descriptor: | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1 | Authors: | Hanawa-Suetsugu, K, Kukimoto-Niino, M, Sekine, S, Ito, T, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S. | Deposit date: | 2009-10-21 | Release date: | 2010-10-27 | Last modified: | 2019-09-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
2DQ3
| |
2D1H
| Crystal structure of ST1889 protein from thermoacidophilic archaeon Sulfolobus tokodaii | Descriptor: | 109aa long hypothetical transcriptional regulator | Authors: | Shinkai, A, Sekine, S, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-08-22 | Release date: | 2006-09-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The putative DNA-binding protein Sto12a from the thermoacidophilic archaeon Sulfolobus tokodaii contains intrachain and interchain disulfide bonds. J.Mol.Biol., 372, 2007
|
|
2YXL
| Crystal Structure of PH0851 | Descriptor: | 450aa long hypothetical fmu protein, SINEFUNGIN | Authors: | Hikida, Y, Kuratani, M, Bessho, Y, Ishii, R, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-26 | Release date: | 2008-04-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structure of an archaeal homologue of the bacterial Fmu/RsmB/RrmB rRNA cytosine 5-methyltransferase Acta Crystallogr.,Sect.D, 66, 2010
|
|
2YYE
| Crystal structure of selenophosphate synthetase from Aquifex aeolicus complexed with AMPCPP | Descriptor: | COBALT (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, PHOSPHATE ION, ... | Authors: | Itoh, Y, Sekine, S, Matsumoto, E, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-29 | Release date: | 2008-04-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of selenophosphate synthetase essential for selenium incorporation into proteins and RNAs J.Mol.Biol., 385, 2009
|
|
2ZUF
| Crystal structure of Pyrococcus horikoshii arginyl-tRNA synthetase complexed with tRNA(Arg) | Descriptor: | Arginyl-tRNA synthetase, tRNA-Arg | Authors: | Konno, M, Sumida, T, Uchikawa, E, Mori, Y, Yanagisawa, T, Sekine, S, Yokoyama, S. | Deposit date: | 2008-10-16 | Release date: | 2009-08-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Modeling of tRNA-assisted mechanism of Arg activation based on a structure of Arg-tRNA synthetase, tRNA, and an ATP analog (ANP) Febs J., 276, 2009
|
|
2ZVF
| Crystal structure of Archaeoglobus fulgidus alanyl-tRNA synthetase C-terminal dimerization domain | Descriptor: | Alanyl-tRNA synthetase, SULFATE ION | Authors: | Naganuma, M, Sekine, S, Fukunaga, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-11-06 | Release date: | 2009-06-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2ZTG
| Crystal structure of Archaeoglobus fulgidus alanyl-tRNA synthetase lacking the C-terminal dimerization domain in complex with Ala-SA | Descriptor: | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, Alanyl-tRNA synthetase, ZINC ION | Authors: | Naganuma, M, Sekine, S, Fukunaga, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-10-01 | Release date: | 2009-06-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2ZUE
| Crystal structure of Pyrococcus horikoshii arginyl-tRNA synthetase complexed with tRNA(Arg) and an ATP analog (ANP) | Descriptor: | Arginyl-tRNA synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Konno, M, Sumida, T, Uchikawa, E, Mori, Y, Yanagisawa, T, Sekine, S, Yokoyama, S. | Deposit date: | 2008-10-16 | Release date: | 2009-08-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Modeling of tRNA-assisted mechanism of Arg activation based on a structure of Arg-tRNA synthetase, tRNA, and an ATP analog (ANP) Febs J., 276, 2009
|
|
5X50
| RNA Polymerase II from Komagataella Pastoris (Type-2 crystal) | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | Authors: | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | Deposit date: | 2017-02-14 | Release date: | 2017-05-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (4.293 Å) | Cite: | Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
|
|
5X51
| RNA Polymerase II from Komagataella Pastoris (Type-3 crystal) | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | Authors: | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | Deposit date: | 2017-02-14 | Release date: | 2017-05-17 | Method: | X-RAY DIFFRACTION (6.996 Å) | Cite: | Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
|
|
5XON
| RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS | Descriptor: | DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S. | Deposit date: | 2017-05-29 | Release date: | 2017-08-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.83 Å) | Cite: | Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
|
|
4WQS
| Thermus thermophilus RNA polymerase backtracked complex | Descriptor: | DNA (28-MER), DNA (5'-D(P*GP*TP*AP*GP*CP*TP*TP*GP*TP*GP*GP*TP*AP*GP*TP*GP*AP*CP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Murayama, Y, Sekine, S, Yokoyama, S. | Deposit date: | 2014-10-22 | Release date: | 2015-02-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (4.306 Å) | Cite: | The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions. Mol.Cell, 57, 2015
|
|
4WQT
| Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GreA/Gfh1 chimeric protein) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Murayama, Y, Sekine, S, Yokoyama, S. | Deposit date: | 2014-10-22 | Release date: | 2015-02-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions. Mol.Cell, 57, 2015
|
|
7YQ8
| Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, 50-mer DNA, DNA topoisomerase 2-beta, ... | Authors: | Naganuma, M, Ehara, H, Kim, D, Nakagawa, R, Cong, A, Bu, H, Jeong, J, Jang, J, Schellenberg, M.J, Bunch, H, Sekine, S. | Deposit date: | 2022-08-05 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes. Nat Commun, 14, 2023
|
|
1IVS
| CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS VALYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(VAL) AND VALYL-ADENYLATE ANALOGUE | Descriptor: | N-[VALINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, Valyl-tRNA synthetase, tRNA (Val) | Authors: | Fukai, S, Nureki, O, Sekine, S.-I, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-03-29 | Release date: | 2003-02-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase RNA, 9, 2003
|
|
6IR9
| RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome | Descriptor: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2018-11-12 | Release date: | 2019-02-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors. Science, 363, 2019
|
|
5MUF
| Crystal structure of human phosphoglycerate mutase family member 5 (PGAM5) in its enzymatically active dodecameric form induced by the presence of the N-terminal WDPNWD motif | Descriptor: | PHOSPHATE ION, Serine/threonine-protein phosphatase PGAM5, mitochondrial | Authors: | Chaikuad, A, Alfano, I, Picaud, S, Filippakopoulos, P, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2017-01-13 | Release date: | 2017-07-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly. Structure, 25, 2017
|
|