3A98
Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1
Summary for 3A98
Entry DOI | 10.2210/pdb3a98/pdb |
Descriptor | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1 (3 entities in total) |
Functional Keywords | protein-protein complex, dock2, elmo1, sh3 domain, ph domain, helix bundle, proline-rich sequence, cytoskeleton, guanine-nucleotide releasing factor, membrane, phosphoprotein, apoptosis, cell membrane, phagocytosis, sh3-binding, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 89621.78 |
Authors | Hanawa-Suetsugu, K.,Kukimoto-Niino, M.,Sekine, S.,Ito, T.,Mishima-Tsumagari, C.,Terada, T.,Shirouzu, M.,Fukui, Y.,Yokoyama, S. (deposition date: 2009-10-21, release date: 2010-10-27, Last modification date: 2019-09-04) |
Primary citation | Hanawa-Suetsugu, K.,Kukimoto-Niino, M.,Mishima-Tsumagari, C.,Akasaka, R.,Ohsawa, N.,Sekine, S.,Ito, T.,Tochio, N.,Koshiba, S.,Kigawa, T.,Terada, T.,Shirouzu, M.,Nishikimi, A.,Uruno, T.,Katakai, T.,Kinashi, T.,Kohda, D.,Fukui, Y.,Yokoyama, S. Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms. Proc.Natl.Acad.Sci.USA, 109:3305-3310, 2012 Cited by PubMed: 22331897DOI: 10.1073/pnas.1113512109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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