3A98

Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Dedicator of cytokinesis protein 2	polymer	184	21402.7	2	UniProt (Q92608) Pfam (PF07653) Pfam (PF16172)	Homo sapiens (human)	DOCK2
2	B, D (B, D)	Engulfment and cell motility protein 1	polymer	203	23408.2	2	UniProt (Q92556) Pfam (PF16457)	Homo sapiens (human)	ELMO1, CED-12 homolog
3	E, F, G, H (A, B, C, D)	water	water		18.0	133	Chemie (HOH)

Sequence modifications

A, C: 1 - 177 (UniProt: Q92608)

PDB	External Database	Details
Gly -6	-	expression tag
Ser -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

B, D: 532 - 727 (UniProt: Q92556)

PDB	External Database	Details
Gly 525	-	expression tag
Ser 526	-	expression tag
Ser 527	-	expression tag
Gly 528	-	expression tag
Ser 529	-	expression tag
Ser 530	-	expression tag
Gly 531	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	89621.8
All*	Total formula weight	89621.8

*Water molecules are not included.