5FMR
 
 | | crIFT52 N-terminal domain | | Descriptor: | INTRAFLAGELLAR TRANSPORT PROTEIN COMPONENT IFT52, SULFATE ION | | Authors: | Mourao, A, Vetter, M, Lorentzen, E. | | Deposit date: | 2015-11-09 | | Release date: | 2016-03-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Intraflagellar Transport Proteins 172, 80, 57, 54, 38, and 20 Form a Stable Tubulin-Binding Ift-B2 Complex.
Embo J., 35, 2016
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6HYI
 | | Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi at 1.4 A resolution in complex with inosine | | Descriptor: | INOSINE, Protein kinase A regulatory subunit | | Authors: | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | | Deposit date: | 2018-10-22 | | Release date: | 2019-11-13 | | Last modified: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (1.39944851 Å) | | Cite: | Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens.
Elife, 12, 2024
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6HYQ
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5FMS
 | | mmIFT52 N-terminal domain | | Descriptor: | INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG | | Authors: | Mourao, A, Lorentzen, E. | | Deposit date: | 2015-11-09 | | Release date: | 2016-03-09 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.488 Å) | | Cite: | Intraflagellar Transport Proteins 172, 80, 57, 54, 38, and 20 Form a Stable Tubulin-Binding Ift-B2 Complex.
Embo J., 35, 2016
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6IAN
 | | T. brucei IFT22/74/81 GTP-bound crystal structure | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Intraflagellar transport protein 74, Intraflagellar transport protein 81, ... | | Authors: | Wachter, S, Basquin, J, Lorentzen, E. | | Deposit date: | 2018-11-27 | | Release date: | 2019-05-01 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly.
Embo J., 38, 2019
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4JA0
 | | Crystal structure of the invertebrate bi-functional purine biosynthesis enzyme PAICS at 2.8 A resolution | | Descriptor: | Phosphoribosylaminoimidazole carboxylase, SULFATE ION | | Authors: | Taschner, M, Basquin, J, Benda, C, Lorentzen, E. | | Deposit date: | 2013-02-18 | | Release date: | 2013-02-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the invertebrate bifunctional purine biosynthesis enzyme PAICS at 2.8 angstrom resolution.
Proteins, 81, 2013
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6FTF
 | | Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi at 1.09 A resolution | | Descriptor: | 1,2-ETHANEDIOL, 7-cyano-7-deazainosine, Protein kinase A regulatory subunit, ... | | Authors: | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | | Deposit date: | 2018-02-21 | | Release date: | 2019-04-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.09151936 Å) | | Cite: | Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma.
Nat Commun, 10, 2019
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6FLO
 | | Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei at 2.1 Angstrom resolution | | Descriptor: | GLYCEROL, INOSINE, Protein kinase A regulatory subunit | | Authors: | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | | Deposit date: | 2018-01-26 | | Release date: | 2019-08-14 | | Last modified: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.13868666 Å) | | Cite: | Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens.
Elife, 12, 2024
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2YC2
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2YC4
 | | Intraflagellar Transport Complex 25-27 from Chlamydomonas | | Descriptor: | CALCIUM ION, CHLORIDE ION, INTRAFLAGELLAR TRANSPORT PROTEIN 25, ... | | Authors: | Bhogaraju, S, Taschner, M, Lorentzen, E. | | Deposit date: | 2011-03-11 | | Release date: | 2011-03-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of the Intraflagellar Transport Complex 25/27.
Embo J., 30, 2011
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4B5O
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4B5P
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6ZL1
 | | Crystal structure of human serum albumin in complex with the MCL-1 neutralizing Alphabody CMPX-383B | | Descriptor: | Albumin, CMPX-383B | | Authors: | Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I. | | Deposit date: | 2020-06-30 | | Release date: | 2021-04-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.272 Å) | | Cite: | Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Sci Adv, 7, 2021
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6ZIE
 | | Crystal structure of MCL-1 in complex with a neutralizing Alphabody CMPX-383B | | Descriptor: | CMPX-383B, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION | | Authors: | Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I. | | Deposit date: | 2020-06-25 | | Release date: | 2021-04-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Sci Adv, 7, 2021
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5N4A
 | | Crystal structure of Chlamydomonas IFT80 | | Descriptor: | GLYCEROL, Intraflagellar transport protein 80, OXALATE ION | | Authors: | Taschner, M, Mourao, A. | | Deposit date: | 2017-02-10 | | Release date: | 2018-02-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis.
Elife, 7, 2018
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2R94
 | | Crystal Structure of KD(P)GA from T.tenax | | Descriptor: | 2-Keto-3-deoxy-(6-phospho-)gluconate aldolase, PYRUVIC ACID | | Authors: | Pauluhn, A, Pohl, E. | | Deposit date: | 2007-09-12 | | Release date: | 2008-03-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax.
Proteins, 72, 2008
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7Q3E
 | | Structure of the mouse CPLANE-RSG1 complex | | Descriptor: | Ciliogenesis and planar polarity effector 2, GUANOSINE-5'-TRIPHOSPHATE, Protein fuzzy homolog, ... | | Authors: | Langousis, G, Cavadini, S, Kempf, G, Matthias, P. | | Deposit date: | 2021-10-27 | | Release date: | 2022-04-06 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structure of the ciliogenesis-associated CPLANE complex.
Sci Adv, 8, 2022
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7Q3D
 | | Structure of the human CPLANE complex | | Descriptor: | Protein fuzzy homolog, Protein inturned, WD repeat-containing and planar cell polarity effector protein fritz homolog | | Authors: | Langousis, G, Cavadini, S, Kempf, G, Matthias, P. | | Deposit date: | 2021-10-27 | | Release date: | 2022-04-06 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structure of the ciliogenesis-associated CPLANE complex.
Sci Adv, 8, 2022
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7OGG
 | | Nse5/6 complex | | Descriptor: | DNA repair protein KRE29,DNA repair protein KRE29,DNA repair protein KRE29, Non-structural maintenance of chromosome element 5,Non-structural maintenance of chromosome element 5,Non-structural maintenance of chromosome element 5 | | Authors: | Basquin, J, Taschner, M, Gruber, S. | | Deposit date: | 2021-05-06 | | Release date: | 2021-07-07 | | Last modified: | 2021-08-11 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding.
Embo J., 40, 2021
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4LVR
 | | Crystal structure of IFT81 N-terminal domain | | Descriptor: | Intraflagellar transport protein 81 | | Authors: | Bhogaraju, S. | | Deposit date: | 2013-07-26 | | Release date: | 2013-09-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81.
Science, 341, 2013
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4LVP
 | | Crystal structure of IFT81 N-terminal domain | | Descriptor: | Intraflagellar transport protein 81, Tantalum | | Authors: | Bhogaraju, S. | | Deposit date: | 2013-07-26 | | Release date: | 2013-09-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.323 Å) | | Cite: | Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81.
Science, 341, 2013
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