6HYI
Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi at 1.4 A resolution in complex with inosine
Summary for 6HYI
| Entry DOI | 10.2210/pdb6hyi/pdb |
| Related | 6FTF |
| Descriptor | Protein kinase A regulatory subunit, INOSINE (3 entities in total) |
| Functional Keywords | protein kinase a, regulatory subunit, cell signalling, signaling protein |
| Biological source | Trypanosoma cruzi |
| Total number of polymer chains | 1 |
| Total formula weight | 35012.51 |
| Authors | Volpato Santos, Y.,Lorentzen, E.,Basquin, J.,Boshart, M. (deposition date: 2018-10-22, release date: 2019-11-13, Last modification date: 2024-04-10) |
| Primary citation | Ober, V.T.,Githure, G.B.,Volpato Santos, Y.,Becker, S.,Moya Munoz, G.,Basquin, J.,Schwede, F.,Lorentzen, E.,Boshart, M. Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens. Elife, 12:-, 2024 Cited by PubMed: 38517938DOI: 10.7554/eLife.91040 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.3994484654 Å) |
Structure validation
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