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5ICT
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BU of 5ict by Molmil
Crystal structure of the Drosophila GluR1A ligand binding domain Y792T mutant complex with glutamate
Descriptor: GLUTAMIC ACID, GLYCEROL, Glutamate receptor 1
Authors:Dharkar, P, Mayer, M.L.
Deposit date:2016-02-23
Release date:2016-12-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Neuron, 92, 2016
2E9A
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BU of 2e9a by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-628
Descriptor: (1-HYDROXY-1-PHOSPHONO-2-[1,1';4',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID, Undecaprenyl pyrophosphate synthetase
Authors:Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J.
Deposit date:2007-01-24
Release date:2007-06-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E9C
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BU of 2e9c by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-675
Descriptor: 1-HYDROXY-2-[3'-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC ACID, Undecaprenyl pyrophosphate synthetase
Authors:Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J.
Deposit date:2007-01-24
Release date:2007-06-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E9D
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BU of 2e9d by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-676
Descriptor: Undecaprenyl pyrophosphate synthetase, [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID)
Authors:Guo, R.T, Cao, R, Ko, T.P, Liang, P.H, Oldfield, E, Wang, A.H.J.
Deposit date:2007-01-24
Release date:2007-06-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E98
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BU of 2e98 by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-629
Descriptor: Undecaprenyl pyrophosphate synthetase, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID
Authors:Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J.
Deposit date:2007-01-24
Release date:2007-06-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E99
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BU of 2e99 by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-608
Descriptor: (1-HYDROXY-1-PHOSPHONO-2-[1,1';3',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID, Undecaprenyl pyrophosphate synthetase
Authors:Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J.
Deposit date:2007-01-24
Release date:2007-06-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
7SJ1
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BU of 7sj1 by Molmil
Structure of shaker-W434F
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker
Authors:Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J.
Deposit date:2021-10-15
Release date:2022-03-30
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of the Shaker Kv channel and mechanism of slow C-type inactivation.
Sci Adv, 8, 2022
7SIP
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BU of 7sip by Molmil
Structure of shaker-IR
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker
Authors:Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J.
Deposit date:2021-10-14
Release date:2022-03-30
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the Shaker Kv channel and mechanism of slow C-type inactivation.
Sci Adv, 8, 2022
7RC8
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BU of 7rc8 by Molmil
Solution NMR Structure of [D-Ala19]Crp4
Descriptor: Alpha-defensin 4
Authors:Conibear, A.C, Rosengren, K.J.
Deposit date:2021-07-07
Release date:2021-08-11
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:A conserved beta-bulge glycine residue facilitates folding and increases stability of the mouse alpha-defensin cryptdin-4
Peptide Science, 114, 2022
6WBR
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BU of 6wbr by Molmil
Crystal structure of AceCas9 bound with guide RNA and DNA with 5'-NNNCC-3' PAM
Descriptor: CRISPR-associated endonuclease, Csn1 family,CRISPR-associated endonuclease, Csn1 family, ...
Authors:Li, H, Das, A.
Deposit date:2020-03-27
Release date:2020-11-18
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:The molecular basis for recognition of 5'-NNNCC-3' PAM and its methylation state by Acidothermus cellulolyticus Cas9.
Nat Commun, 11, 2020
6WC0
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BU of 6wc0 by Molmil
Crystal structure of AceCas9 bound with guide RNA and DNA with 5'-NNNTC-3' PAM
Descriptor: CRISPR-associated endonuclease, Csn1 family, DNA (30-MER), ...
Authors:Li, H, Das, A.
Deposit date:2020-03-28
Release date:2020-11-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:The molecular basis for recognition of 5'-NNNCC-3' PAM and its methylation state by Acidothermus cellulolyticus Cas9.
Nat Commun, 11, 2020
2QRI
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BU of 2qri by Molmil
Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb WT, beta-2microglobulin, and ovalbumin-derived peptide.
Descriptor: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
Authors:Mitaksov, V.E, Fremont, D.H.
Deposit date:2007-07-28
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2QRT
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BU of 2qrt by Molmil
Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C, beta-2microglobulin, and ovalbumin-derived peptide.
Descriptor: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
Authors:Mitaksov, V.E, Fremont, D.H.
Deposit date:2007-07-29
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2QRS
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BU of 2qrs by Molmil
Crystal Structure of a single chain trimer composed of the MHC I heavy chain H-2Kb Y84A, beta-2microglobulin, and ovalbumin-derived peptide.
Descriptor: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
Authors:Mitaksov, V.E, Fremont, D.H.
Deposit date:2007-07-29
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
8Q7O
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BU of 8q7o by Molmil
Crystal structure of the FZD3 cysteine-rich domain in complex with a nanobody (14478)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, DIMETHYL SULFOXIDE, ...
Authors:Hillier, J.S, Zhao, Y, Malinauskas, T, Jones, E.Y.
Deposit date:2023-08-16
Release date:2024-08-28
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural insights into Frizzled3 through nanobody modulators.
Nat Commun, 15, 2024
8QW4
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BU of 8qw4 by Molmil
FZD3 in complex with nanobody 9
Descriptor: Frizzled-3, Nanobody Nb9
Authors:Zhao, Y, Jones, E.Y.
Deposit date:2023-10-18
Release date:2024-09-04
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural insights into Frizzled3 through nanobody modulators.
Nat Commun, 15, 2024
4DZB
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BU of 4dzb by Molmil
Mucosal-associated invariant T cell receptor, Valpha7.2Jalpha33-Vbeta2
Descriptor: Valpha7.2-Jalpha33 (MAIT T cell receptor), Vbeta2 (MAIT T cell receptor)
Authors:Patel, O, Rossjohn, J.
Deposit date:2012-03-01
Release date:2012-03-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor.
J.Exp.Med., 209, 2012
4HKJ
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BU of 4hkj by Molmil
Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb)
Descriptor: Beta-2-microglobulin, CPXV203 protein, H-2 class I histocompatibility antigen, ...
Authors:McCoy IV, W.H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-10-15
Release date:2012-11-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Mechanism of ER Retrieval of MHC Class I by Cowpox.
Plos Biol., 10, 2012
3UO1
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BU of 3uo1 by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
Descriptor: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
Authors:Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
Deposit date:2011-11-16
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3UYR
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BU of 3uyr by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
Descriptor: 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ...
Authors:Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
Deposit date:2011-12-06
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
4LCW
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BU of 4lcw by Molmil
The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH
Descriptor: 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Patel, O, Rossjohn, J.
Deposit date:2013-06-24
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells.
J.Exp.Med., 210, 2013
3V4U
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BU of 3v4u by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
Descriptor: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
Authors:Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
Deposit date:2011-12-15
Release date:2012-07-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
4KXR
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BU of 4kxr by Molmil
Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer
Descriptor: EspG5, PE25, PPE41
Authors:Korotkova, N, Creekmore, C.C, Korotkov, K.V.
Deposit date:2013-05-27
Release date:2014-05-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer.
Mol.Microbiol., 94, 2014
5XWR
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BU of 5xwr by Molmil
Crystal Structure of RBBP4-peptide complex
Descriptor: Histone-binding protein RBBP4, MET-SER-ARG-ARG-LYS-GLN-ALA-LYS-PRO-GLN-HIS-ILE
Authors:Jobichen, C, Lui, B.H, Daniel, G.T, Sivaraman, J.
Deposit date:2017-06-30
Release date:2018-07-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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