3JQR
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3OZ1
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![BU of 3oz1 by Molmil](/molmil-images/mine/3oz1) | cIAP1-BIR3 domain in complex with the Smac-mimetic compound Smac066 | Descriptor: | (3S,6S,7R,9aS)-7-[2-(benzylamino)ethyl]-N-(diphenylmethyl)-6-{[(2S)-2-(methylamino)butanoyl]amino}-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide, Baculoviral IAP repeat-containing protein 2, ZINC ION | Authors: | Cossu, F, Malvezzi, F, Mastrangelo, E, Canevari, G, Bolognesi, M, Milani, M. | Deposit date: | 2010-09-24 | Release date: | 2010-11-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Recognition of Smac-mimetic compounds by the BIR3 domain of cIAP1 Protein Sci., 2010
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1MBI
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![BU of 1mbi by Molmil](/molmil-images/mine/1mbi) | X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION | Descriptor: | IMIDAZOLE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Lionetti, C, Guanziroli, M.G, Frigerio, F, Ascenzi, P, Bolognesi, M. | Deposit date: | 1990-06-25 | Release date: | 1991-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution. J.Mol.Biol., 217, 1991
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3NA4
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![BU of 3na4 by Molmil](/molmil-images/mine/3na4) | D53P beta-2 microglobulin mutant | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Beta-2-microglobulin | Authors: | Azinas, S, Ricagno, S, Bolognesi, M. | Deposit date: | 2010-06-01 | Release date: | 2011-06-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | D-strand perturbation and amyloid propensity in beta-2 microglobulin Febs J., 278, 2011
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3QZZ
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![BU of 3qzz by Molmil](/molmil-images/mine/3qzz) | 3D Structure of Ferric Methanosarcina Acetivorans Protoglobin Y61W mutant in Aquomet form | Descriptor: | Methanosarcina acetivorans protoglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Pesce, A, Tilleman, L, Dewilde, S, Ascenzi, P, Coletta, M, Ciaccio, C, Bruno, S, Moens, L, Bolognesi, M, Nardini, M. | Deposit date: | 2011-03-07 | Release date: | 2011-06-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants. Iubmb Life, 63, 2011
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6I2Z
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![BU of 6i2z by Molmil](/molmil-images/mine/6i2z) | Isolated globin domain of the Bordetella pertussis globin-coupled sensor | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Uncharacterized protein | Authors: | Germani, F, De Schutter, A, Cuypers, B, Berghmans, H, Van Hauwaert, M.-L, Bruno, S, Mozzarelli, A, Moens, L, Van Doorslaer, S, Bolognesi, M, Pesce, A, Dewilde, S. | Deposit date: | 2018-11-02 | Release date: | 2019-10-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and Functional Characterization of the Globin-Coupled Sensors ofAzotobacter vinelandiiandBordetella pertussis. Antioxid.Redox Signal., 32, 2020
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1Y9O
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![BU of 1y9o by Molmil](/molmil-images/mine/1y9o) | 1H NMR Structure of Acylphosphatase from the hyperthermophile Sulfolobus Solfataricus | Descriptor: | Acylphosphatase | Authors: | Corazza, A, Rosano, C, Pagano, K, Alverdi, V, Esposito, G, Capanni, C, Bemporad, F, Plakoutsi, G, Stefani, M, Chiti, F, Zuccotti, S, Bolognesi, M, Viglino, P. | Deposit date: | 2004-12-16 | Release date: | 2005-11-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus Proteins, 62, 2006
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3R0G
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![BU of 3r0g by Molmil](/molmil-images/mine/3r0g) | 3D Structure of Ferric Methanosarcina Acetivorans Protoglobin I149F mutant in Aquomet form | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Pesce, A, Tilleman, L, Dewilde, S, Ascenzi, P, Coletta, M, Ciaccio, C, Bruno, S, Moens, L, Bolognesi, M, Nardini, M. | Deposit date: | 2011-03-08 | Release date: | 2011-06-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants. Iubmb Life, 63, 2011
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3QZX
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![BU of 3qzx by Molmil](/molmil-images/mine/3qzx) | 3D Structure of ferric methanosarcina acetivorans protoglobin Y61A mutant with unknown ligand | Descriptor: | GLYCEROL, Methanosarcina acetivorans protoglobin, PHOSPHATE ION, ... | Authors: | Pesce, A, Tilleman, L, Dewilde, S, Ascenzi, P, Coletta, M, Ciaccio, C, Bruno, S, Moens, L, Bolognesi, M, Nardini, M. | Deposit date: | 2011-03-07 | Release date: | 2011-06-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants. Iubmb Life, 63, 2011
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7NP4
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![BU of 7np4 by Molmil](/molmil-images/mine/7np4) | cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | Authors: | Giese, H, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A. | Deposit date: | 2021-02-26 | Release date: | 2021-08-11 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
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7NP3
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![BU of 7np3 by Molmil](/molmil-images/mine/7np3) | cAMP-free rabbit HCN4 stabilized in LMNG-CHS detergent mixture | Descriptor: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | Authors: | Giese, H.M, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A. | Deposit date: | 2021-02-26 | Release date: | 2021-08-11 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
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1YIO
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![BU of 1yio by Molmil](/molmil-images/mine/1yio) | Crystallographic structure of response regulator StyR from Pseudomonas fluorescens | Descriptor: | MAGNESIUM ION, MERCURY (II) ION, response regulatory protein | Authors: | Milani, M, Leoni, L, Rampioni, G, Zennaro, E, Ascenzi, P, Bolognesi, M. | Deposit date: | 2005-01-12 | Release date: | 2005-09-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | An Active-like Structure in the Unphosphorylated StyR Response Regulator Suggests a Phosphorylation- Dependent Allosteric Activation Mechanism STRUCTURE, 13, 2005
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2BJD
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![BU of 2bjd by Molmil](/molmil-images/mine/2bjd) | Sulfolobus Solfataricus Acylphosphatase. Triclinic space group | Descriptor: | ACYLPHOSPHATASE, CADMIUM ION, CHLORIDE ION, ... | Authors: | Rosano, C, Zuccotti, S, Bolognesi, M. | Deposit date: | 2005-02-02 | Release date: | 2005-11-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus. Proteins: Struct., Funct., Bioinf., 62, 2006
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1LHS
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![BU of 1lhs by Molmil](/molmil-images/mine/1lhs) | LOGGERHEAD SEA TURTLE MYOGLOBIN (AQUO-MET) | Descriptor: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Nardini, M, Tarricone, C, Lania, A, Desideri, A, De Sanctis, G, Coletta, M, Petruzzelli, R, Ascenzi, P, Coda, A, Bolognesi, M. | Deposit date: | 1995-02-01 | Release date: | 1995-06-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Reptile heme protein structure: X-ray crystallographic study of the aquo-met and cyano-met derivatives of the loggerhead sea turtle (Caretta caretta) myoglobin at 2.0 A resolution. J.Mol.Biol., 247, 1995
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1LHT
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![BU of 1lht by Molmil](/molmil-images/mine/1lht) | LOGGERHEAD SEA TURTLE MYOGLOBIN (CYANO-MET) | Descriptor: | CYANIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Nardini, M, Tarricone, C, Lania, A, Desideri, A, De Sanctis, G, Coletta, M, Petruzzelli, R, Ascenzi, P, Coda, A, Bolognesi, M. | Deposit date: | 1995-02-01 | Release date: | 1995-06-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Reptile heme protein structure: X-ray crystallographic study of the aquo-met and cyano-met derivatives of the loggerhead sea turtle (Caretta caretta) myoglobin at 2.0 A resolution. J.Mol.Biol., 247, 1995
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2QRW
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![BU of 2qrw by Molmil](/molmil-images/mine/2qrw) | Crystal structure of Mycobacterium tuberculosis trHbO WG8F mutant | Descriptor: | CYANIDE ION, Hemoglobin-like protein HbO, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Milani, M, Bolognesi, M. | Deposit date: | 2007-07-30 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | The Roles of Tyr(CD1) and Trp(G8) in Mycobacterium tuberculosis Truncated Hemoglobin O in Ligand Binding and on the Heme Distal Site Architecture Biochemistry, 46, 2007
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1ZN2
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![BU of 1zn2 by Molmil](/molmil-images/mine/1zn2) | Low Resolution Structure of Response Regulator StyR | Descriptor: | MAGNESIUM ION, response regulatory protein | Authors: | Milani, M, Leoni, L, Rampioni, G, Zennaro, E, Ascenzi, P, Bolognesi, M. | Deposit date: | 2005-05-11 | Release date: | 2005-09-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | An Active-like Structure in the Unphosphorylated StyR Response Regulator Suggests a Phosphorylation- Dependent Allosteric Activation Mechanism. STRUCTURE, 13, 2005
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1QHA
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![BU of 1qha by Molmil](/molmil-images/mine/1qha) | HUMAN HEXOKINASE TYPE I COMPLEXED WITH ATP ANALOGUE AMP-PNP | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Rosano, C, Sabini, E, Deriu, D, Magnani, M, Bolognesi, M. | Deposit date: | 1999-05-11 | Release date: | 1999-11-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control. Structure Fold.Des., 7, 1999
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7ZIR
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![BU of 7zir by Molmil](/molmil-images/mine/7zir) | Cryo-EM structure of hnRNPDL amyloid fibrils | Descriptor: | Heterogeneous nuclear ribonucleoprotein D-like | Authors: | Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S. | Deposit date: | 2022-04-08 | Release date: | 2022-12-28 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3. Nat Commun, 14, 2023
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1FLP
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![BU of 1flp by Molmil](/molmil-images/mine/1flp) | STRUCTURE OF THE SULFIDE-REACTIVE HEMOGLOBIN FROM THE CLAM LUCINA PECTINATA: CRYSTALLOGRAPHIC ANALYSIS AT 1.5 ANGSTROMS RESOLUTION | Descriptor: | HEMOGLOBIN I (AQUO MET), PROTOPORPHYRIN IX CONTAINING FE | Authors: | Rizzi, M, Wittenberg, J.B, Ascenzi, P, Fasano, M, Coda, A, Bolognesi, M. | Deposit date: | 1994-05-16 | Release date: | 1994-07-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the sulfide-reactive hemoglobin from the clam Lucina pectinata. Crystallographic analysis at 1.5 A resolution. J.Mol.Biol., 244, 1994
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8A11
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![BU of 8a11 by Molmil](/molmil-images/mine/8a11) | Cryo-EM structure of the Human SHMT1-RNA complex | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, cytosolic | Authors: | Spizzichino, S, Marabelli, C, Bharadwaj, A, Jakobi, A.J, Chaves-Sanjuan, A, Giardina, G, Bolognesi, M, Cutruzzola, F. | Deposit date: | 2022-05-30 | Release date: | 2023-06-14 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1. Mol.Cell, 2024
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1MOH
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![BU of 1moh by Molmil](/molmil-images/mine/1moh) | FERRIC MONOMERIC HEMOGLOBIN I (HB I) | Descriptor: | HYDROSULFURIC ACID, MONOMERIC HEMOGLOBIN I, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Rizzi, M, Wittenberg, J.B, Ascenzi, P, Bolognesi, M. | Deposit date: | 1996-02-27 | Release date: | 1996-08-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural bases for sulfide recognition in Lucina pectinata hemoglobin I. J.Mol.Biol., 258, 1996
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2OXT
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![BU of 2oxt by Molmil](/molmil-images/mine/2oxt) | Crystal structure of Meaban virus nucleoside-2'-O-methyltransferase | Descriptor: | NUCLEOSIDE-2'-O-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE | Authors: | Mastrangelo, E, Milani, M, Bollati, M, Bolognesi, M. | Deposit date: | 2007-02-21 | Release date: | 2007-05-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase Protein Sci., 16, 2007
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5AB8
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![BU of 5ab8 by Molmil](/molmil-images/mine/5ab8) | High resolution X-ray structure of the N-terminal truncated form (residues 1-11) of Mycobacterium tuberculosis HbN | Descriptor: | ACETATE ION, FORMIC ACID, GLYCEROL, ... | Authors: | Pesce, A, Bustamante, J.P, Bidon-Chanal, A, Boechi, L, Estrin, D.A, Luque, F.J, Sebilo, A, Guertin, M, Bolognesi, M, Ascenzi, P, Nardini, M. | Deposit date: | 2015-08-04 | Release date: | 2015-11-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | The N-Terminal Pre-A Region of Mycobacterium Tuberculosis 2/2Hbn Promotes No-Dioxygenase Activity. FEBS J., 283, 2016
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5CKA
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![BU of 5cka by Molmil](/molmil-images/mine/5cka) | Human beta-2 microglobulin double mutant W60G-N83V | Descriptor: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | Deposit date: | 2015-07-15 | Release date: | 2016-05-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability. Sci Rep, 6, 2016
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