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5G5J
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BU of 5g5j by Molmil
Crystal structure of human CYP3A4 bound to metformin
Descriptor: CYTOCHROME P450 3A4, Metformin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sevrioukova, I.
Deposit date:2016-05-25
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.
Cell Chem Biol, 24, 2017
7TTR
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BU of 7ttr by Molmil
Skd3_ATPyS_FITC-casein Hexamer, AAA+ only
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Beta-casein, Caseinolytic peptidase B protein homolog, ...
Authors:Rizo, A.N.
Deposit date:2022-02-01
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3.
Cell Rep, 40, 2022
7TTS
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BU of 7tts by Molmil
Skd3, hexamer, filtered
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Beta-casein, Caseinolytic peptidase B protein homolog, ...
Authors:Rizo, A.N, Cupo, R.R.
Deposit date:2022-02-01
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3.
Cell Rep, 40, 2022
2LOC
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BU of 2loc by Molmil
Conotoxin analogue [D-Ala2]BuIIIB
Descriptor: Mu-conotoxin BuIIIB
Authors:Kuang, Z.
Deposit date:2012-01-21
Release date:2013-01-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mammalian neuronal sodium channel blocker mu-conotoxin BuIIIB has a structured N-terminus that influences potency.
Acs Chem.Biol., 8, 2013
2LO9
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BU of 2lo9 by Molmil
NMR solution structure of Mu-contoxin BuIIIB
Descriptor: Mu-conotoxin BuIIIB
Authors:Kuang, Z.
Deposit date:2012-01-20
Release date:2013-01-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mammalian neuronal sodium channel blocker mu-conotoxin BuIIIB has a structured N-terminus that influences potency.
Acs Chem.Biol., 8, 2013
2M62
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BU of 2m62 by Molmil
Solution Structure of a Chi/Lambda Conotoxin fron Conus araneosus
Descriptor: Chi-conotoxin-like Ar1248
Authors:Sarma, S.P, Ganesan, S, Gowd K, H, Padmanabhan, B.
Deposit date:2013-03-19
Release date:2014-04-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution Structure of Ar1248, a Chi/Lambda conotoxin from Conus araneosus
To Be Published
2LXG
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BU of 2lxg by Molmil
NMR solution structure of Mu-conotoxin KIIIA
Descriptor: Mu-conotoxin KIIIA
Authors:Khoo, K.K, Norton, R.S.
Deposit date:2012-08-21
Release date:2013-02-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Distinct disulfide isomers of mu-conotoxins KIIIA and KIIIB block voltage-gated sodium channels.
Biochemistry, 51, 2012
5YJE
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BU of 5yje by Molmil
Crystal structure of HIRA(644-1017)
Descriptor: Protein HIRA, SULFATE ION
Authors:Sato, Y, Senda, M, Senda, T.
Deposit date:2017-10-10
Release date:2018-06-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit
Nat Commun, 9, 2018
8TRG
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BU of 8trg by Molmil
Structure of full-length LexA bound to a RecA filament
Descriptor: DNA (27-MER), LexA repressor, MAGNESIUM ION, ...
Authors:Cory, M.B, Li, A, Kohli, R.M.
Deposit date:2023-08-09
Release date:2023-11-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:The LexA-RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation.
Nat.Struct.Mol.Biol., 2024
5DEN
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BU of 5den by Molmil
The First Structure of a Full-Length Mammalian Phenylalanine Hydroxylase Reveals the Architecture of an Auto-inhibited Tetramer
Descriptor: FE (III) ION, Phenylalanine-4-hydroxylase
Authors:Arturo, E.C, Loll, P.J, Jaffe, E.K.
Deposit date:2015-08-25
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer.
Proc.Natl.Acad.Sci.USA, 113, 2016
7N9H
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BU of 7n9h by Molmil
Structure of the mammalian importin a1 bound to the TDP-43 NLS
Descriptor: Importin subunit alpha-1, TAR DNA-binding protein 43
Authors:Doll, S.G, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
7LZ9
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BU of 7lz9 by Molmil
Inactive form of VanR from S. coelicolor
Descriptor: MAGNESIUM ION, Putative two-component system response regulator
Authors:Maciunas, L.J, Loll, P.J.
Deposit date:2021-03-09
Release date:2021-07-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states.
Acta Crystallogr D Struct Biol, 77, 2021
7LZA
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BU of 7lza by Molmil
Activated form of VanR from S. coelicolor
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Putative two-component system response regulator
Authors:Maciunas, L.J, Loll, P.J.
Deposit date:2021-03-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states.
Acta Crystallogr D Struct Biol, 77, 2021
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