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1SL0
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BU of 1sl0 by Molmil
Ternary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template and an incoming nucleotide
Descriptor: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', ...
Authors:Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T.
Deposit date:2004-03-05
Release date:2004-07-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
2OYQ
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BU of 2oyq by Molmil
Crystal structure of RB69 gp43 in complex with DNA with 5-NIMP opposite an abasic site analog
Descriptor: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ...
Authors:Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
Deposit date:2007-02-22
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Biochemistry, 46, 2007
2P5G
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BU of 2p5g by Molmil
Crystal structure of RB69 gp43 in complex with DNA with dAMP opposite an abasic site analog in a 21mer template
Descriptor: DNA polymerase, Primer DNA, Template DNA
Authors:Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
Deposit date:2007-03-15
Release date:2007-10-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Biochemistry, 46, 2007
2OZS
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BU of 2ozs by Molmil
Crystal structure of RB69 gp43 in complex with DNA with dATP opposite dTMP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, MAGNESIUM ION, ...
Authors:Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
Deposit date:2007-02-27
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Biochemistry, 46, 2007
2OZM
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BU of 2ozm by Molmil
Crystal structure of RB69 gp43 in complex with DNA with 5-NITP opposite an abasic site analog
Descriptor: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ...
Authors:Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
Deposit date:2007-02-26
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Caught Bending the A-Rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide
Biochemistry, 46, 2007
2P5O
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BU of 2p5o by Molmil
Crystal structure of RB69 GP43 in complex with DNA containing an abasic site analog
Descriptor: DNA polymerase, Primer DNA, Template DNA
Authors:Hogg, M, Wallace, S.S, Doublie, S.
Deposit date:2007-03-15
Release date:2007-04-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site.
Embo J., 23, 2004
4M9L
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BU of 4m9l by Molmil
DNA Polymerase Beta E295K Soaked with dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA Downstream Strand, DNA Primer Strand, ...
Authors:Eckenroth, B.E, Doublie, S.
Deposit date:2013-08-14
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:The E295K Cancer Variant of Human Polymerase beta Favors the Mismatch Conformational Pathway during Nucleotide Selection.
J.Biol.Chem., 288, 2013
4M9G
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BU of 4m9g by Molmil
DNA Polymerase Beta E295K Binary Complex
Descriptor: CHLORIDE ION, DNA Downstream Strand, DNA Primer Strand, ...
Authors:Eckenroth, B.E, Doublie, S.
Deposit date:2013-08-14
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The E295K Cancer Variant of Human Polymerase beta Favors the Mismatch Conformational Pathway during Nucleotide Selection.
J.Biol.Chem., 288, 2013
4LT6
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BU of 4lt6 by Molmil
Crystal Structure of human poly(A) polymerase gamma
Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Poly(A) polymerase gamma
Authors:Yang, Q, Nausch, L, Martin, G, Keller, W, Doublie, S.
Deposit date:2013-07-23
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Crystal structure of human poly(a) polymerase gamma reveals a conserved catalytic core for canonical poly(a) polymerases.
J.Mol.Biol., 426, 2014
4M9H
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BU of 4m9h by Molmil
DNA Polymerase Beta E295K Soaked with dTTP
Descriptor: CHLORIDE ION, DNA Downstream Strand, DNA Primer Strand, ...
Authors:Eckenroth, B.E, Doublie, S.
Deposit date:2013-08-14
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:The E295K Cancer Variant of Human Polymerase beta Favors the Mismatch Conformational Pathway during Nucleotide Selection.
J.Biol.Chem., 288, 2013
4M9N
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BU of 4m9n by Molmil
DNA Polymerase Beta E295K Soaked with dATP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA Downstream Strand, DNA Primer Strand, ...
Authors:Eckenroth, B.E, Doublie, S.
Deposit date:2013-08-14
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.275 Å)
Cite:The E295K Cancer Variant of Human Polymerase beta Favors the Mismatch Conformational Pathway during Nucleotide Selection.
J.Biol.Chem., 288, 2013
4M9J
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BU of 4m9j by Molmil
DNA Polymerase Beta E295K Soaked with dUMPNPP
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA Downstream Strand, ...
Authors:Eckenroth, B.E, Doublie, S.
Deposit date:2013-08-14
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.038 Å)
Cite:The E295K Cancer Variant of Human Polymerase beta Favors the Mismatch Conformational Pathway during Nucleotide Selection.
J.Biol.Chem., 288, 2013
4MB7
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BU of 4mb7 by Molmil
Crystal Structure of a viral DNA glycosylase
Descriptor: Endonuclease 8-like L720, SULFATE ION, ZINC ION
Authors:Prakash, A, Eckenroth, B.E, Doublie, S.
Deposit date:2013-08-19
Release date:2013-10-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural investigation of a viral ortholog of human NEIL2/3 DNA glycosylases.
Dna Repair, 12, 2013
4NRW
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BU of 4nrw by Molmil
MvNei1-G86D
Descriptor: 5'-D(*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3', 5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', formamidopyrimidine-DNA glycosylase
Authors:Prakash, A, Doublie, S.
Deposit date:2013-11-27
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.845 Å)
Cite:Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing.
Dna Repair, 14, 2014
4NRV
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BU of 4nrv by Molmil
Crystal Structure of non-edited human NEIL1
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endonuclease 8-like 1
Authors:Prakash, A, Doublie, S.
Deposit date:2013-11-27
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing.
Dna Repair, 14, 2014
3KD5
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BU of 3kd5 by Molmil
Closed ternary complex of an RB69 gp43 fingers domain mutant complexed with an acyclic GMP terminated primer template pair and phosphonoformic acid.
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(4DG))-3'), DNA polymerase, ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2009-10-22
Release date:2011-04-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase.
J.Biol.Chem., 286, 2011
3KD1
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BU of 3kd1 by Molmil
Closed binary complex of an RB69 gp43 fingers domain mutant complexed with an acyclic GMP terminated primer template pair.
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(4DG))-3'), DNA polymerase, ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2009-10-22
Release date:2011-04-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase.
J.Biol.Chem., 286, 2011
3KNT
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BU of 3knt by Molmil
Crystal structure of Methanocaldococcus jannaschii 8-oxoguanine glycosylase/lyase in complex with 15mer DNA containing 8-oxoguanine
Descriptor: 5'-D(*AP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', N-glycosylase/DNA lyase, ...
Authors:Faucher, F, Doublie, S.
Deposit date:2009-11-12
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The C-terminal Lysine of Ogg2 DNA Glycosylases is a Major Molecular Determinant for Guanine/8-Oxoguanine Distinction.
J.Mol.Biol., 397, 2010
3I0X
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BU of 3i0x by Molmil
Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing adenine opposite to 8-oxoG
Descriptor: 5'-D(*AP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*AP*TP*GP*GP*A)-3', 8-oxoguanine-DNA-glycosylase, ...
Authors:Faucher, F, Doublie, S.
Deposit date:2009-06-25
Release date:2009-09-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase.
Dna Repair, 8, 2009
3I0W
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BU of 3i0w by Molmil
Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing cytosine opposite to 8-oxoG
Descriptor: 1,2-ETHANEDIOL, 5'-D(*AP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*A)-3', ...
Authors:Faucher, F, Doublie, S.
Deposit date:2009-06-25
Release date:2009-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase.
Dna Repair, 8, 2009
3L8B
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BU of 3l8b by Molmil
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin
Descriptor: DNA (5'-D(*AP*C*TP*(G35)P*TP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*A)-3'), DNA polymerase, ...
Authors:Aller, P, Ye, Y, Wallace, S.S, Burrows, C.J, Doublie, S.
Deposit date:2009-12-30
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin.
Biochemistry, 49, 2010
3LDS
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BU of 3lds by Molmil
Crystal structure of RB69 gp43 with DNA and dATP opposite 8-oxoG
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*(8OG)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(DDG))-3'), ...
Authors:Hogg, M, Midkiff, J, Rudnicki, J, Reha-Krantz, L, Doublie, S, Wallace, S.S.
Deposit date:2010-01-13
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69.
Biochemistry, 49, 2010
3MDG
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BU of 3mdg by Molmil
Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im in complex with RNA UUGUAU
Descriptor: Cleavage and polyadenylation specificity factor subunit 5, GLYCEROL, RNA (5'-R(*UP*UP*GP*UP*AP*U)-3')
Authors:Yang, Q, Gilmartin, G.M, Doublie, S.
Deposit date:2010-03-30
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OTB
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BU of 3otb by Molmil
Crystal structure of human tRNAHis guanylyltransferase (Thg1) - dGTP complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRIPHOSPHATE, ...
Authors:Hyde, S.J, Eckenroth, B.E, Doublie, S.
Deposit date:2010-09-11
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OTE
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BU of 3ote by Molmil
Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native I
Descriptor: tRNA(His) guanylyltransferase
Authors:Hyde, S.J, Eckenroth, B.E, Doublie, S.
Deposit date:2010-09-11
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.
Proc.Natl.Acad.Sci.USA, 107, 2010

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PDB entries from 2024-10-16

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