3L8B

Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin

Summary for 3L8B

• Entry DOI: 10.2210/pdb3l8b/pdb
• Related: 1IG9 1Q9Y 2DY4 2P5O
• Descriptor: DNA polymerase, DNA (5'-D(*AP*C*TP*(G35)P*TP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*A)-3'), ... (5 entities in total)
• Functional Keywords: dna polymerase rb69 gp43, protein-dna complex, oxidative dna lesion, guanidinohydantoin, dna replication, dna-binding, dna-directed dna polymerase, exonuclease, hydrolase, nuclease, nucleotidyltransferase, transferase, transferase-dna complex, transferase/dna
• Biological source: Enterobacteria phage RB69 (Bacteriophage RB69)
• Total number of polymer chains: 6
• Total formula weight: 229359.68

Authors

Aller, P.,Ye, Y.,Wallace, S.S.,Burrows, C.J.,Doublie, S. (deposition date: 2009-12-30, release date: 2010-03-09, Last modification date: 2023-09-06)

• Primary citation: Aller, P.,Ye, Y.,Wallace, S.S.,Burrows, C.J.,Doublie, S.; Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin.; Biochemistry, 49:2502-2509, 2010; PubMed: 20166752; DOI: 10.1021/bi902195p

Experimental method

X-RAY DIFFRACTION (2.15 Å)