3L8B
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DNA polymerase | polymer | 906 | 105069.6 | 2 | UniProt (Q38087) Pfam (PF03104) Pfam (PF00136) In PDB | Enterobacteria phage RB69 (Bacteriophage RB69) | Gp43 |
2 | C, E | DNA (5'-D(*AP*C*TP*(G35)P*TP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3') | polymer | 18 | 5522.6 | 2 | |||
3 | D, F | DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*A)-3') | polymer | 13 | 3991.6 | 2 | |||
4 | B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
5 | water | water | 18.0 | 998 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 903 (UniProt: Q38087)
PDB | External Database | Details |
---|---|---|
Ala 222 | Asp 222 | engineered mutation |
Ala 327 | Asp 327 | engineered mutation |
His 904 | - | expression tag |
His 905 | - | expression tag |
His 906 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 229167.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 192.1 | |
All* | Total formula weight | 229359.7 |